ELSA Italy

In the last 50 years, Italy has experienced a relevant transformation, starting from an emigrant nation (according to the last statistics from the Ministry of the Interior, there are more than 4.636.647 Italians still living abroad) to become an immigrant destination. From 1970 until now, migrant citizens with regular residence permits in Italy have increased, with a rate of growth that looks almost unstoppable: at the beginning of 2017, there were more than 5,047,028 foreign nationals resident in Italy. This numbers, added to the illegal immigrants whose numbers are difficult to define, outline a complex situation, characterized by immigrant flows from almost 200 different countries, especially Central Eastern Europe (Albania, Romania and Ukraine), Northern Africa (Morocco), China and the Indian subcontinent (Pakistan, India, and Sri Lanka). This historically important phenomenon requires in-depth analysis in order to evaluate the effectiveness of the Italian legislation and intervention policies, and to find concrete solutions to help immigrants settling in our country

Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead

There is growing interest in non-invasive brain stimulation (NIBS) as a novel treatment option for substance-use disorders (SUDs). Recent momentum stems from a foundation of preclinical neuroscience demonstrating links between neural circuits and drug consuming behavior, as well as recent FDA-approval of NIBS treatments for mental health disorders that share overlapping pathology with SUDs. As with any emerging field, enthusiasm must be tempered by reason; lessons learned from the past should be prudently applied to future therapies. Here, an international ensemble of experts provides an overview of the state of transcranial-electrical (tES) and transcranial-magnetic (TMS) stimulation applied in SUDs. This consensus paper provides a systematic literature review on published data – emphasizing the heterogeneity of methods and outcome measures while suggesting strategies to help bridge knowledge gaps. The goal of this effort is to provide the community with guidelines for best practices in tES/TMS SUD research. We hope this will accelerate the speed at which the community translates basic neuroscience into advanced neuromodulation tools for clinical practice in addiction medicine

Evaluation of compliance to telehomecare (THC) in a group of patients with Cystic Fibrosis (CF) in a period of 2 years

Objectives. In the present study, we examined data related to adherence to telemonitoring in our CF patients followed at home for a period of 2 years, in the aim to improve the follow-up in terms of efficiency and appropriateness. Materials and Methods. We kept electronic records of transmissions, in spreadsheet format. For each transmission, the main parameters and any action taken were collected. We carried out automatically a monthly summary of activities, a monthly average percentage of adherence to prescribed frequency of transmissions, monitored the contacts and phone calls. Results. We received in the period from February 15, 2010 to February 15, 2012 overall 1364 transmissions in 515 days (1817 spirometry, 414 nocturnal pulse-oximetry and 398 questionnaires on symptoms) The average compliance in the reporting period was 10,16%, with an increasing trend. Conclusions. The improvement of outcome in FC necessarily passes through an improvement of the adherence to treatment. More psychological and behavioural studies are needed in order to gradually remove the obstacles which still prevent a further improvement in long-term outcome

Ictal video-polysomnography and EEG spectral analysis in a child with severe Panayiotopoulos syndrome

To describe the ictal polysomnographic features of a patient with Panayiotopoulos syndrome, a peculiar epileptic syndrome characterized by infrequent, often single, prolonged, nocturnal, focal seizures comprising an unusual constellation of autonomic symptoms (malaise, nausea, pallor, tachycardia, vomiting) and unilateral deviation of the eyes at the onset of seizures. These clinical, ictal manifestations are rarely followed by post-ictal headache. In the literature, there is little information on the ictal EEG characteristics of Panayiotopoulos syndrome and, in particular, on certain autonomic manifestations, such as tachycardia, as the sole ictal phenomena at the onset of seizures. Methods and results. One, all-night videopolysomnography, during which one seizure was recorded. Video-EEG data were evaluated visually and by means of quantitative spectral analysis. The spectral analysis of the recorded seizure showed a complex ictal pattern of cortical involvement with focal onset in the right occipital area followed by the recruitment of widespread extraoccipital cortical regions. Conclusions. This is the first such analysis of this peculiar epileptic condition. Most of the symptoms were consistent with a diagnosis of severe Panayiotopoulos syndrome, although the patient also presented “atypical findings”: a relatively high frequency of seizures, post-ictal headache, no spontaneous remission of seizures with age, and late onset of visual hallucinations; this last finding is more frequent in ″Gastaut-type childhood occipital epilepsy″, in which onset typically occurs later than in Panayiotopoulos syndrome