Cambios en las proteínas plasmáticas totales de madres y crías por efecto del cortisol

Se estudia en ratas la influencia de la gestación y el cortisol sobre el contenido en proteínas plasmáticas totales de madres y crías. Se observa que la gestación no modifica el nivel de proteínas plasmáticas, mientras que el cortisol incrementa significativamente dicho parámetro tanto en ratas no gestantes como en las gestantes y en sus crías.We study in rats the influence of the gestation and the cortisol in the complet tContained in plasma proteins of mothers and newsborn. We observe that the gestation don't change the level of plasma proteins while the cortisol augment this parameter equal in no gestants rats as in gestants and in their newsborn

Light driven water oxidation by a single site cobalt salophen catalyst

A salophen cobalt(II) complex enables water oxidation at neutral pH in photoactivated sacrificial cycles under visible light, thus confirming the high appeal of earth abundant single site catalysis for artificial photosynthesis

Estudio detallado de los efectos del acetato de hidrocortisona durante la gestación sobre el número de fetos y abortos en la rata

Se estudia la evolución del efecto de la administración de acetato de hidrocortisona (4mg/100 g. peso/día) a ratas sobre el número de fetos y abortos de la camada en los días 6, 9, 12, 14, 16, 18 y 21 de gestación. Se observa que el acetato de hidrocortisona disminuye el número de fetos vivos a partir del día 17 de tratamiento siendo la disminución más acusada en el día 21, en el que la diferencia respecto al grupo control es de un 25%. El acetato de hidrocortisona incrementa el porcentaje de ratas que presentan abortos en cualquiera de los periodos estudiados. Además en el día 14 el 22,2% de ratas inyectadas con acetato de hidrocortisona presentan abortos de la totalidad de sus fetos, hecho que nunca sucede en las ratas control. En el día 21 es más acusado el efecto de la hormona ya que mientras que las ratas testigo mantienen todos los fetos vivos, un 66% de ratas tratadas con cortisona siguen presentando abortos.The evolution of the effect of the administration of hydrocortisone aceta te (HA) (4mg/l00g weightlday) to the pregnant rat on the number of viable and nonviable fetuses was studied on days 6, 9, 12, 14, 16, 18 and 21 of gesta tion . . The administration of HA to pregnant rats reduced the number of live fe tuses starting on day 17 of treatment representing a loss of approximately 25% of the fetuses when they are compared with the control rats. High doses of cortisone acetate were seen to increase the percentage of rats whose uterus contained dead fetuses at any given period of study. On day 14 more over the entire litter was found to have died in utero in 22,2% of all cortisol injected rats, a finding which never occurred in controls. The effects of cortisol were most in evidence on day 21, when all fetuses were viable in controls as opposed to hormone-treated rats, 66% of which were found to contain nonviable fetuses

Estudio detallado de los efectos del acetato de hidrocortisona durante la gestación sobre el número de fetos y abortos en la rata

The evolution of the effect of the administration of hydrocortisone acetate (HA) (4mg/100g weightlday) to the pregnant rat on the number of viable and nonviable fetuses was studied on days 6, 9, 12, 14, 16, 18 and 21 of gestation. The administration of HA to pregnant rats reduced the number of live fetuses starting on day 17 of treatment representing a loss of approximately 25% of the fetuses when they are compared with the control rats. High doses of cortisone acetate were seen to increase the percentage of rats whose uterus contained dead fetuses at any given period of study. On day 14 more over the entire litter was found to have died in utero in 22,2% of all cortisol injected rats, a finding which never occurred in controls. The effects of cortisol were most in evidence on day 21, when all fetuses were viable in controls as opposed to hormone-treated rats, 66% of which were found to contain nonviable fetuses.Se estudia la evolución del efecto de la administración de acetato de hidrocortisona (4mg/100 g. peso/día) a ratas sobre el número de fetos y abortos de la camada en los días 6, 9, 12, 14, 16, 18 y 21 de gestación. Se observa que el acetato de hidrocortisona disminuye el número de fetos vivos a partir del día 17 de tratamiento siendo la disminución más acusada en el día 21, en el que la diferencia respecto al grupo control es de un 25%. El acetato de hidrocortisona incrementa el porcentaje de ratas que presentan abortos en cualquiera de los periodos estudiados. Además en el día 14 el 22,2% de ratas inyectadas con acetato de hidrocortisona presentan abortos de la totalidad de sus fetos, hecho que nunca sucede en las ratas control. En el día 21 es más acusado el efecto de la hormona ya que mientras que las ratas testigo mantienen todos los fetos vivos, un 66% de ratas tratadas con cortisona siguen presentando abortos

Español

Se estudia en ratas la influencia de la gestación y el cortisol sobre el contenido en proteínas plasmáticas totales de madres y crías. Se observa que la gestación no modifica el nivel de proteínas plasmáticas, mientras que el cortisol incrementa significativamente dicho parámetro tanto en ratas no gestantes como en las gestantes y en sus crías.We study in rats the influence of the gestation and the cortisol in the complet tContained in plasma proteins of mothers and newsborn. We observe that the gestation don't change the level of plasma proteins while the cortisol augment this parameter equal in no gestants rats as in gestants and in their newsborn

A Co(II)-Ru(II) dyad relevant to light-driven water oxidation catalysis

Artificial photosynthesis aims at efficient water splitting into hydrogen and oxygen, by exploiting solar light. As a priority requirement, this process entails the integration of suitable multi-electron catalysts with light absorbing units, where charge separation is generated in order to drive the catalytic routines. The final goal could be the transposition of such an asset into a photoelectrocatalytic cell, where the two half-reactions, proton reduction to hydrogen and water oxidation to oxygen, take place at two appropriately engineered photoelectrodes. We herein report a covalent approach to anchor a Co(II) water oxidation catalyst to a Ru(II) polypyridine photosensitizer unit; photophysical characterisation and the catalytic activity of such a dyad in a light activated cycle are reported, and implications for the development of regenerative systems are discussedArtificial photosynthesis aims at efficient water splitting into hydrogen and oxygen, by exploiting solar light. As a priority requirement, this process entails the integration of suitable multi-electron catalysts with light absorbing units, where charge separation is generated in order to drive the catalytic routines. The final goal could be the transposition of such an asset into a photoelectrocatalytic cell, where the two half-reactions, proton reduction to hydrogen and water oxidation to oxygen, take place at two appropriately engineered photoelectrodes. We herein report a covalent approach to anchor a Co(II) water oxidation catalyst to a Ru(II) polypyridine photosensitizer unit; photophysical characterisation and the catalytic activity of such a dyad in a light activated cycle are reported, and implications for the development of regenerative systems are discussed

Light driven water oxidation by a single site Cobalt Salophen catalyst

A salophen cobalt(II) complex enables water oxidation at neutral pH in photoactivated sacrificial cycles with visible light, thus confirming the high appeal of earth abundant single site catalysis for artificial photosynthesi

Knitting the catalytic pattern of artificial photosynthesis to a hybrid graphene nanotexture

The artificial leaf project calls for new materials enabling multielectron catalysis with minimal overpotential, high turnover frequency, and long-term stability. Is graphene a better material than carbon nanotubes to enhance water oxidation catalysis for energy applications? Here we show that functionalized graphene with a tailored distribution of polycationic, quaternized, ammonium pendants provides an sp2 carbon nanoplatform to anchor a totally inorganic tetraruthenate catalyst, mimicking the oxygen evolving center of natural PSII. The resulting hybrid material displays oxygen evolution at overpotential as low as 300 mV at neutral pH with negligible loss of performance after 4 h testing. This multilayer electroactive asset enhances the turnover frequency by 1 order of magnitude with respect to the isolated catalyst, and provides a definite up-grade of the carbon nanotube material, with a similar surface functionalization. Our innovation is based on a noninvasive, synthetic protocol for graphene functionalization that goes beyond the ill-defined oxidationreduction methods, allowing a definite control of the surface properties