Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences.

Abstract: A novel property of DNA is described: the capacity of some bacterial DNA sequences to induce electromagnetic waves at high aqueous dilutions. It appears to be a resonance phenomenon triggered by the ambient electromagnetic background of very low frequency waves. The genomic DNA of most pathogenic bacteria contains sequences which are able to generate such signals. This opens the way to the development of highly sensitive detection system for chronic bacterial infections in human and animal diseases

Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences.

Abstract: A novel property of DNA is described: the capacity of some bacterial DNA sequences to induce electromagnetic waves at high aqueous dilutions. It appears to be a resonance phenomenon triggered by the ambient electromagnetic background of very low frequency waves. The genomic DNA of most pathogenic bacteria contains sequences which are able to generate such signals. This opens the way to the development of highly sensitive detection system for chronic bacterial infections in human and animal diseases

Transduction of DNA information through water and electromagnetic waves

The experimental conditions by which electromagnetic signals (EMS) of low frequency can be emitted by diluted aqueous solutions of some bacterial and viral DNAs are described. That the recorded EMS and nanostructures induced in water carry the DNA information (sequence) is shown by retrieval of that same DNA by classical PCR amplification using the TAQ polymerase, including both primers and nucleotides. Moreover, such a transduction process has also been observed in living human cells exposed to EMS irradiation. These experiments suggest that coherent long range molecular interaction must be at work in water so to allow the observed features. The quantum field theory analysis of the phenomenon is presented.Comment: 10 pages, 6 figure

Limited Viral Spread and Rapid Immune Response in Lymph Nodes of Macaques Inoculated with Attenuated Simian Immunodeficiency Virus

AbstractA comparative study was undertaken to characterize the very early events that distinguish attenuated and pathogenic simian immunodeficiency virus (SIV) infections. Three rhesus macaques were inoculated with the attenuated SIVmac 251 Δnef virus, and three others with a virus of intermediate phenotype, SIVmac 239 nef stop. They were compared to four macaques inoculated with the pathogenic SIVmac 251 isolate. Lymph nodes (LN) taken between 7 days and 2 months postinoculation were analyzed for SIV expression byin situhybridization. During acute infection, SIV 251 Δnef infected 1 to 1.5 log10fewer cells in LN tissue than the pathogenic SIV 251 isolate. The reduction was more marked in the blood, as SIV 251 Δnef infected 2 to 3 log10fewer PBMC than the isolate and did not yield detectable antigenemia. Morphometric measurements showed that the development of germinal centers (GC) was more rapid in the Δnef infection, which led to a more efficient trapping of viral particles, and could account for antigenemia clearance. The SIV 239 nef stop clone reverted to a nef+genotype at Week 2, but induced a lower viral burden than a directly pathogenic virus. The kinetics of GC development was rapid, indicating that SIV 239 nef stop induced an immune response similar to that seen in attenuated infection. This study provides evidence that attenuated SIV elicits a more rapid immune response than pathogenic SIV and suggests that an early immunosuppressive episode may facilitate the dissemination of pathogenic SIV

MECANISME D'IMPORT NUCLEAIRE DU GENOME HIV APPLICATIONS A LA VECTOROLOGIE ET AU TRANSFERT DE GENE

L'INITIATION ET LA TERMINAISON CENTRALE DE LA SYNTHESE DU BRIN PLUS, UNIQUE A LA RETROTRANSCRIPTION DES LENTIVIRUS, CONDUIT A LA FORMATION D'UNE STRUCTURE A TROIS BRINS DE 99 NUCLEOTIDES DE LONG (L'ADN FLAP CENTRAL) AU MILIEU DE L'ADN LINEAIRE NON INTEGRE. DES MUTATIONS DANS LE CPPT ET LE CTS, LES SEQUENCES CIS-ACTIVES IMPLIQUEES DANS LA FORMATION DE L'ADN FLAP CENTRAL, ALTERE PROFONDEMENT L'INFECTIVITE DU VIRUS. L'ADN RETROTRANSCRIT DES VIRUS MUTANTS NE POSSEDANT PAS D'ADN FLAP CENTRAL EST BLOQUE A UN STADE LINEAIRE, AU VOISINAGE DE LA MEMBRANE NUCLEAIRE, AU LIEU D'ENTRER DANS LE NOYAU ET DE SE CIRCULARISER OU DE S'INTEGRER. L'ADN LINEAIRE DES MUTANTS DU FLAP GARDE SA CAPACITE A S'INTEGRER IN VITRO. NOUS PROPOSONS UN MECANISME D'IMPORT NUCLEAIRE DE L'ADN GENOMIQUE DU HIV DANS LEQUEL LA STRATEGIE DE RETROTRANSCRIPTION DES LENTIVIRUS CREEE UN ADN FLAP CENTRAL QUI EST IMPLIQUE DANS LA MATURATION DU COMPLEXE DE RETROTRANSCRIPTION EN COMPLEXE DE PRE-INTEGRATION ET DANS LA TRANSLOCATION DE L'ADN VIRAL A TRAVERS LE PORE NUCLEAIRE. L'IMPORT NUCLEAIRE ACTIF ET DONC LA REPLICATION INDEPENDANTE DE LA MITOSE FAIT DES LENTIVIRUS DE BON CANDIDATS POUR LES APPLICATIONS DE TRANSFERT DE GENE. LES VECTEURS LENTIVIRAUX DOIVENT INCLURE LES DETERMINANTS DE L'IMPORT NUCLEAIRE POUR REALISER UNE TRANSDUCTION EFFICACE DE CELLULES CIBLES NON MITOTIQUES. LES VECTEURS RETROVIRAUX CLASSIQUES DITS DE REMPLACEMENT NE SONT PAS OPTIMAUX POUR CETTE OPTIQUE. NOUS AVONS DONC INSERE L'ADN FLAP CENTRAL DANS UN SYSTEME DE VECTEUR DERIVE DU HIV. NOUS AVONS OBSERVE UNE FORTE AUGMENTATION DU TITRE DES VECTEURS DANS DIFFERENTS TYPES DE CELLULES, IN VITRO COMME DANS LES CELLULES HELA ARRETEES OU NON, LES CELLULES PRIMAIRES DE MOELLE EPINIERE OU LES CELLULES SOUCHES (EC ET HSC), AUSSI BIEN QU'IN VIVO PAR INJECTION DIRECTE DANS LE CERVEAU DE RAT. NOUS CORRELONS CETTE AUGMENTATION DE LA TRANSDUCTION DE GENE AVEC UNE COMPLEMENTATION, A UN NIVEAU SAUVAGE, DE L'IMPORT NUCLEAIRE DES VECTEURS DEPOURVUS D'ADN FLAP CENTRAL.PARIS-BIUSJ-Thèses (751052125) / SudocCentre Technique Livre Ens. Sup. (774682301) / SudocPARIS-BIUSJ-Physique recherche (751052113) / SudocSudocFranceF

Para ahli menjawab tentang AIDS/ Luc Montagnier (et al)

xiv, 168 hal. : ill. ; 19 cm