47 research outputs found
We Say - Look Before You Snap
In advice to amateurs, Kathryn Monson suggests looking twice before snapping that pictur
Changing Beliefs about Trauma: A Qualitative Study of Cognitive Processing Therapy
Background: Controlled qualitative methods complement quantitative treatment outcome research and enable a more thorough understanding of the effects of therapy and the suspected mechanisms of action. Aims: Thematic analyses were used to examine outcomes of cognitive processing therapy (CPT) for posttraumatic stress disorder (PTSD) in a randomized controlled trial of individuals diagnosed with military-related PTSD ( n = 15). Method: After sessions 1 and 11, participants wrote “impact statements” describing their appraisals of their trauma and beliefs potentially impacted by traumatic events. Trained raters coded each of these statements using a thematic coding scheme. Results: An analysis of thematic coding revealed positive changes over the course of therapy in participants’ perspective on their trauma and their future, supporting the purported mechanisms of CPT. Conclusion: Implications of this research for theory and clinical practice are discussed
Pulmonary metastasectomy in colorectal cancer: health utility scores by EQ-5D-3L in a randomized controlled trial show no benefit from lung metastasectomy.
AIM: The aim was to assess the health utility of lung metastasectomy in the treatment of patients with colorectal cancer (CRC) using the EQ-5D-3L questionnaire. METHODS: Multidisciplinary CRC teams at 14 sites recruited patients to a two-arm randomized controlled trial-Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC). Remote randomization was used, stratified by site and with minimization for seven known confounders. Participants completed the EQ-5D-3L questionnaire together with other patient reported outcome measures at randomization and then again at 3, 6, 12 and 24 months. These were returned by post to the coordinating centre. RESULTS: Between December 2010 and December 2016, 93 participants were randomized, 91 of whom returned questionnaires. Survival and patient reported quality of life have been published previously, revealing no significant differences between the trial arms. Described here are patient reported data from the five dimensions of the EQ-5D-3L and the visual analogue scale (VAS) health state. No significant difference was seen at any time point. The estimated difference between control and metastasectomy patients was -0.23 (95% CI -0.113, 0.066) for the composite 0 to 1 index scale based on the descriptive system and 0.123 (95% CI -7.24, 7.49) for the 0 to 100 VAS scale. CONCLUSIONS: Following lung metastasectomy for CRC, no benefit was demonstrated for health utility, which alongside a lack of a survival or quality of life benefit calls into question the widespread use of the procedure
Anger-Related Dysregulation as a Factor Linking Childhood Physical Abuse and Interparental Violence to Intimate Partner Violence Experiences
Childhood family violence exposure is associated with increased risk for experiencing intimate partner violence (IPV) in adulthood, but the mechanisms underlying this relationship remain inadequately understood. Difficulties with emotion regulation may be one factor that helps to explain this relationship
The Iowa Homemaker vol.20, no.1
Recreation that Recreates, Editor, page 1
Dual Personalities, Catherine Raymond, page 2
Married Right Out of College, Mary Ellen Lynch Brown, page 3
Sally Bows to Summer’s Sun, Kathryn Cooley, page 4
Selling Yourself, Kathryn Monson, page 6
I Want a Cotton Dress, Marcia E. Turner, page 7
Playtime Pays Dividends, Jane Wiley, page 8
Behind Closed Doors, Margaret Kumlien, page 9
Sunshine Sports, Jeanette Woodward, page 10
Packing the Convention Bag, Shirley Ambrose, page 11
What’s New in Home Economics, page 12
Veishea Presents, Adelaide Richardson, page 14
Picnic Basket, Dorothy Jo Weber, page 16
Alums in the News, Bette Simpson, page 17
Make Room for Music, Nancy Mason, page 18
Behind Bright Jackets, Betty Bice, page 20
Journalistic Spindles, Dorothy Anne Roost, page 23
Biography of a Home Economist, Eleanor White, page 2
The Iowa Homemaker vol.19, no.1
Dedication, page 2
There’s Research Excitement, page 3
The Chem E’s Soybean, page 4
A Past Editor Goes to Town, page 5
Sally Previews, page 6
Let Letters Live, page 8
Bridal Showers Forecast, page 9
What’s New in Home Economics, page 10
Building a Little House in Print, page 12
Danforth Play Time, page 13
Behind Bright Jackets, page 14
Alums in the News, page 15
Gay Commencement Colors, page 16
An Activities Ace, page 17
It’s Veishea Time, page 18
From Journalistic Spindles, page 19
Biography of a Home Economist, page 2
The Iowa Homemaker vol.21, no.3
Freshmen – Please Note, page 2
Hospital Research, Ann Koebel, page 3
Orchids to Pat, page 4
The Army Eats Well, Mary I. Barber, page 5
Making Things Grow, Betty Ann Iverson, page 6
Look Before You Snap, Kathryn Monson, page 7
Major Departments on Review, Elizabeth Murfield, page 8
Patriotic Sally, Patricia Hayes, page 10
What’s New in Home Economics, Dorothy Olson, page 12
Summer Job Holders Reap Experience, page 14
A List of Don’ts, Costume Design Class, page 15
We Salute Campus Leaders, Margaret Kirchner, page 16
Home Economics Looks to Future, M. L. Morton, page 17
Behind Bright Jackets, Julie Wendel, page 18
Alums in the News, Mary Elizabeth Sather, page 20
Nutrition for Defense, Dorothy Ann Roost, page 22
That Personal Touch, Margaret Ann Clarke, page 23
Journalistic Spindles, Elizabeth Hanson, page 2
Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial
BACKGROUND: Lung metastasectomy in the treatment of advanced colorectal cancer has been widely adopted without good evidence of survival or palliative benefit. We aimed to test its effectiveness in a randomised controlled trial (RCT).
METHODS: Multidisciplinary teams in 13 hospitals recruited participants with potentially resectable lung metastases to a multicentre, two-arm RCT comparing active monitoring with or without metastasectomy. Other local or systemic treatments were decided by the local team. Randomisation was remote and stratified by site with minimisation for age, sex, primary cancer stage, interval since primary resection, prior liver involvement, the number of metastases, and carcinoembryonic antigen level. The central Trial Management Group were blind to patient allocation until completion of the analysis. Analysis was on intention to treat with a margin for non-inferiority of 10%.
RESULTS: Between December 2010 and December 2016, 65 participants were randomised. Characteristics were well-matched in the two arms and similar to those in reported studies: age 35 to 86 years (interquartile range (IQR) 60 to 74); primary resection IQR 16 to 35 months previously; stage at resection T1, 2 or 3 in 3, 8 and 46; N1 or N2 in 31 and 26; unknown in 8. Lung metastases 1 to 5 (median 2); 16/65 had previous liver metastases; carcinoembryonic antigen normal in 55/65. There were no other interventions in the first 6 months, no crossovers from control to treatment, and no treatment-related deaths or major adverse events. The Hazard ratio for death within 5 years, comparing metastasectomy with control, was 0.82 (95%CI 0.43, 1.56).
CONCLUSIONS: Because of poor and worsening recruitment, the study was stopped. The small number of participants in the trial (N = 65) precludes a conclusive answer to the research question given the large overlap in the confidence intervals in the proportions still alive at all time points. A widely held belief is that the 5-year absolute survival benefit with metastasectomy is about 35%: 40% after metastasectomy compared to < 5% in controls. The estimated survival in this study was 38% (23-62%) for metastasectomy patients and 29% (16-52%) in the well-matched controls. That is the new and important finding of this RCT. TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT01106261. Registered on 19 April 2010
SMHASH:A new mid-infrared RR Lyrae distance determination for the Local Group dwarf spheroidal galaxy Sculptor
We present a new distance estimation for the Milky Way dwarf spheroidal
satellite Sculptor obtained from multi-epoch mid-infrared observations of RR
Lyrae stars. The 3.6 {\mu}m observations have been acquired with the Infrared
Array Camera on board the Spitzer Space Telescope as part of the SMHASH
Program. Mid-infrared light curves for 42 RRL were obtained, from which we
measured Sculptor's distance modulus to be {\mu} = 19.60 0.02
(statistical) 0.04 (photometric) mag (with = 0.09 mag),
using the 3.6 {\mu}m empirical period-luminosity relations derived from the
Galactic globular cluster M4, or {\mu} = 19.57 0.02 (statistical)
0.04 (photometric) mag (with = 0.11 mag) using empirical
relations in the same passband recently derived from the Large Magellanic Cloud
globular cluster Reticulum. Both these measurements are in good agreement with
values presented in previous works with Sculptor RR Lyrae stars in optical
bands, and are also consistent with recent near-infrared RR Lyrae results. Best
agreement with the literature is found for the latter modulus which is
equivalent to a distance of d = 82 1 (statistical) 2 (photometric)
kpc (with = 4 kpc). Finally, using a subsample of RR Lyrae
stars with spectroscopic metallicities, we demonstrate that these distance
estimates are not affected by metallicity effects.Comment: 24 pages, 11 figures. Accepted for publication in MNRA