2 research outputs found
Influence of voluntary contractions on the basal sEMG activity of the pelvic floor muscles
[EN] Chronic pelvic pain (CPP) is a complex clinical condition that
affects many women, being sometimes misdiagnosed or
mistreated,which can be treated with the infiltration of botulinum
toxin (BoNTA). The pelvic floor musculature (PFM) condition
from CPP patients can be assessed by means of surface
electromyography (sEMG). The evaluation of the basal activity
can help to detect a muscular dysfunction, therefore it is
important to ensure that the PFM shows a minimum activation
when its sEMG is being analysed. In this study, we recorded the
sEMG of 25 women with CPP before and 8, 12 and 24 weeks after
their treatment with BoNTA while they performed a protocol of 5
voluntary contractions. The root mean square (RMS) and sample
entropy (SampEn) of basal segments pre- (B[PRE]), inter- (B[I])
and post- (B[POST]) contractions of the sEMG were computed
and normalized according to the minimum (RMSnorm) and
maximum (SampEnorm) of the recording. B(PRE) showed the
lowest RMSnorm median both before and after the treatment with
BoNTA, which proved that the activity of the PFM is minimum
before the first contraction. As for SampEnnorm, although results
were not so conclusive, they also indicated that B(PRE) should
be taken as a reference to analyse the PFM function at its state of
minimum activity. Future works aiming to characterize the effects
of BoNTA in PFM by means of sEMG should consider basal
segments before contractions to assess basal tone conditions.This study was funded by ISCIII, MCIU, VLC Campus in
Convocatoria Ayudas: UPV-La Fe (INBIO): 2016 SPEHG
(ID:C18), 2019 sEMG_BONTAv (ID:C06) and with funds
from private contracts with Merz Pharma España S.L.Albaladejo-Belmonte, M.; Tarazona-Motes, M.; Nohales-Alfonso, FJ.; Alberola-Rubio, J.; Garcia-Casado, J. (2020). Influence of voluntary contractions on the basal sEMG activity of the pelvic floor muscles. Sociedad Española de IngenierĂa BiomĂ©dica. 240-243. http://hdl.handle.net/10251/178256S24024
Treatment of Vestibulodynia with Submucosal Injections of IncobotulinumtoxinA into Targeted Painful Points: An Open-Label Exploratory Study
The studies carried out to date on vulvodynia treatment with botulinum neurotoxin type A (BoNT/A) have followed generic injection protocols and reported contradictory outcomes on its effects. The aim of the present study was thus to propose a protocol for injecting BoNT/A into targeted painful points, to comprehensively assess the clinical effect of BoNT/A treatment and identify the risk/protective factors for successful treatment. Thirty-five vestibulodynia patients were treated with submucosal injections of incobotulinumtoxinA and assessed 8, 12 and 24 weeks after their treatment. Their clinical and pelvic statuses were assessed from self-reported questionnaires (Visual Analogue Scale (VAS), Female Sexual Function Index (FSFI), Marinoff’s Dyspareunia Scale (MDS), Hospital Anxiety and Depression Scale (HADS), Catastrophizing Scale (CS)), physical examinations and surface electromyography (sEMG). The patients reported a reduction in provoked vestibulodynia (p FSFI, p p = 0.01) and psychological status (p p = 0.01). Factors such as smoking, painful comorbidities, vulvar pain sensitivity and sexual function were significantly associated with successful treatment. The results indicate the beneficial effects of BoNT/A in treating vestibulodynia and reinforce the importance of adapting the treatment according to its clinical presentation and the patient’s medical background