A Primary Testicular Diffuse Large B-cell Lymphoma Belonging to the Germinal Center B-cell-like Group

Testicular lymphoma was first reported by Malassez and Curling in 1866. Primary testicular lymphoma constitutes only 1 - 7% of all testicular neoplasms and less than 1% of all non Hodgkin lymphoma. The authors report a new case of primary testicular lymphoma and highlight its diagnostic and therapeutic challenge. We report the case of a 26-year old man without a particular past medical history, who presented with a painful right testicular swelling that he has noticed for several weeks. Radiological findings consisted in multiple hypoechoic masses that corresponded in histological examination to a diffuse intratubular lymphomatous infiltration situated away from the spermatic cord, the epididymis, ductuli efferentes and rete testis. Immunohistochemical study showed positivity for leukocytic common antigen (CD45), B-cell marker (CD20) and bcl 6. The patient underwent full staging for lymphoma showing no evidence of extra-testicular involvement by lymphoma and no lymph nodes. The diagnosis of stage I primary testicular large B-cell lymphoma of germinal center B-cell-like group was made. The patient is now treated by chemotherapy. Primary testicular lymphoma is a rare tumour whose diagnosis is based on histological findings. There are non consensual etiological or predisposing factors. Treatment modalities consist in surgical excision, chemotherapy and radiation therapy but the accurate procedures are not standardized. Factors that have been linked to more favorable outcomes include younger patient age, localized disease, presence of sclerosis at pathologic analysis, smaller tumour size, lower histological tumor grade and lack of epididymal or spermatic cord involvement

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Salivary gland cystadenocarcinoma of the tongue: A case report and literature review

Cystadenocarcinoma is a rare salivary gland tumor which commonly arises in the ovary and the appendix. Only 7 cases have been reported in the tongue with 2 cases described as highly malignant. We report a case of cystadenocarcinoma of the base of the tongue in a 79-year-old man who presented with goiter and dysphagia. Physical examination showed a mass of the tongue. Treatment consisted in a partial glossectomy. The patient was free of recurrences after one year of follow up. Cystadenocarcinoma of the tongue is a very rare tumor on which diagnosis is based on histological findings. The treatment is based on surgical excision. These tumours are reported to have a good prognosis but some cases have been described reported to recur even after many years of follow up. Key words: Cystadenocarcinoma, base of the tongue