Plasmons in Sodium under Pressure: Increasing Departure from Nearly-Free-Electron Behavior

We have measured plasmon energies in Na under high pressure up to 43 GPa using inelastic x-ray scattering (IXS). The momentum-resolved results show clear deviations, growing with increasing pressure, from the predictions for a nearly-free electron metal. Plasmon energy calculations based on first-principles electronic band structures and a quasi-classical plasmon model allow us to identify a pressure-induced increase in the electron-ion interaction and associated changes in the electronic band structure as the origin of these deviations, rather than effects of exchange and correlation. Additional IXS results obtained for K and Rb are addressed briefly.Comment: 5 pages, 4 figure

Defect formation in superconducting rings: external fields and finite-size effects

Consistent with the predictions of Kibble and Zurek, scaling behaviour has been seen in the production of fluxoids during temperature quenches of superconducting rings. However, deviations from the canonical behaviour arise because of finite-size effects and stray external fields. Technical developments, including laser heating and the use of long Josephson tunnel junctions, have improved the quality of data that can be obtained. With new experiments in mind we perform large-scale 3D simulations of quenches of small, thin rings of various geometries with fully dynamical electromagnetic fields, at nonzero externally applied magnetic flux. We find that the outcomes are, in practice, indistinguishable from those of much simpler Gaussian analytical approximations in which the rings are treated as one-dimensional systems and the magnetic field fluctuation-free.Comment: 10 pages, 3 figures, presentation at QFS2012, to appear in JLT

Characterizing Diffused Stellar Light in simulated galaxy clusters

[Abridged] In this paper, we carry out a detailed analysis of the performance of two different methods to identify the diffuse stellar light in cosmological hydrodynamical simulations of galaxy clusters. One method is based on a dynamical analysis of the stellar component. The second method is closer to techniques commonly employed in observational studies. Both the dynamical method and the method based on the surface brightness limit criterion are applied to the same set of hydrodynamical simulations for a large sample about 80 galaxy clusters. We find significant differences between the ICL and DSC fractions computed with the two corresponding methods, which amounts to about a factor of two for the AGN simulations, and a factor of four for the CSF set. We also find that the inclusion of AGN feedback boosts the DSC and ICL fractions by a factor of 1.5-2, respectively, while leaving the BCG+ICL and BCG+DSC mass fraction almost unchanged. The sum of the BCG and DSC mass stellar mass fraction is found to decrease from ~80 per cent in galaxy groups to ~60 per cent in rich clusters, thus in excess of what found from observational analysis. We identify the average surface brightness limits that yields the ICL fraction from the SBL method close to the DSC fraction from the dynamical method. These surface brightness limits turn out to be brighter in the CSF than in the AGN simulations. This is consistent with the finding that AGN feedback makes BCGs to be less massive and with shallower density profiles than in the CSF simulations. The BCG stellar component, as identified by both methods, are slightly older and more metal-rich than the stars in the diffuse component.Comment: 18 Pages, 15 figures. Matches to MNRAS published versio

Observation of the onset of strong scattering on high frequency acoustic phonons in densified silica glass

The linewidth of longitudinal acoustic waves in densified silica glass is obtained by inelastic x-ray scattering. It increases with a high power alpha of the frequency up to a crossover where the waves experience strong scattering. We find that \alpha is at least 4, and probably larger. Resonance and hybridization of acoustic waves with the boson-peak modes seems to be a more likely explanation for these findings than Rayleigh scattering from disorder.Comment: 4 pages, 4 figures, to appear in Phys. Rev. Letter

The cloud-in-cloud problem for non-Gaussian density fields

The cloud-in-cloud problem is studied in the context of the extension to non-Gaussian density fields of the Press-Schechter approach for the calculation of the mass function. As an example of a non-Gaussian probability distribution functions (PDFs) we consider the Chi-square, with various degrees of freedom. We generate density fields in cubic boxes with periodic boundary conditions and then determine the number of points considered collapsed at each scale through an hierarchy of smoothing windows. We find that the mass function we obtain differs from that predicted using the Extended Press-Schechter formalism, particularly for low values of $\sigma$ and for those PDFs most distinct from a Gaussian.Comment: 5 pages, LaTex using mn.sty, matches published version, results for the Inverted Chi-square distribution withdraw

High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a

The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry. The rapid increase of resistance to therapeutic agents, as well as the expense of vaccination with live attenuated vaccines, requires the development of new effective treatments for coccidiosis. Because of their key regulatory function in the eukaryotic cell cycle, cyclin-dependent kinases (CDKs) are prominent drug targets. The Eimeria tenella CDC2-related kinase 2 (EtCRK2) is a validated drug target that can be activated in vitro by the CDK activator XlRINGO (Xenopus laevis rapid inducer of G2/M progression in oocytes). Bioinformatics analyses revealed four putative E. tenella cyclins (EtCYCs) that are closely related to cyclins found in the human apicomplexan parasite Plasmodium falciparum. EtCYC3a was cloned, expressed in Escherichia coli and purified in a complex with EtCRK2. Using the non-radioactive time-resolved fluorescence energy transfer (TR-FRET) assay, we demonstrated the ability of EtCYC3a to activate EtCRK2 as shown previously for XlRINGO. The EtCRK2/EtCYC3a complex was used for a combined in vitro and in silico high-throughput screening approach, which resulted in three lead structures, a naphthoquinone, an 8-hydroxyquinoline and a 2-pyrimidinyl-aminopiperidine-propane-2-ol. This constitutes a promising starting point for the subsequent lead optimization phase and the development of novel anticoccidial drugs

Academic freedom in Europe: reviewing UNESCO’s recommendation

This paper examines the compliance of universities in the European Union with the UNESCO Recommendation concerning the Status of Higher–Education Teaching Personnel, which deals primarily with protection for academic freedom. The paper briefly surveys the European genesis of the modern research university and academic freedom, before evaluating compliance with the UNESCO recommendation on institutional autonomy, academic freedom, university governance and tenure. Following from this, the paper examines the reasons for the generally low level of compliance with the UNESCO Recommendation within the EU states, and considers how such compliance could be improved

Elastic constant dishomogeneity and Q2Q^2 dependence of the broadening of the dynamical structure factor in disordered systems

We propose an explanation for the quadratic dependence on the momentum $Q$, of the broadening of the acoustic excitation peak recently found in the study of the dynamic structure factor of many real and simulated glasses. We ascribe the observed $Q^2$ law to the spatial fluctuations of the local wavelength of the collective vibrational modes, in turn produced by the dishomegeneity of the inter-particle elastic constants. This explanation is analitically shown to hold for 1-dimensional disordered chains and satisfatorily numerically tested in both 1 and 3 dimensions.Comment: 4 pages, RevTeX, 5 postscript figure

Gauge-theoretic invariants for topological insulators: A bridge between Berry, Wess-Zumino, and Fu-Kane-Mele

We establish a connection between two recently-proposed approaches to the understanding of the geometric origin of the Fu-Kane-Mele invariant $\mathrm{FKM} \in \mathbb{Z}_2$, arising in the context of 2-dimensional time-reversal symmetric topological insulators. On the one hand, the $\mathbb{Z}_2$ invariant can be formulated in terms of the Berry connection and the Berry curvature of the Bloch bundle of occupied states over the Brillouin torus. On the other, using techniques from the theory of bundle gerbes it is possible to provide an expression for $\mathrm{FKM}$ containing the square root of the Wess-Zumino amplitude for a certain $U(N)$-valued field over the Brillouin torus. We link the two formulas by showing directly the equality between the above mentioned Wess-Zumino amplitude and the Berry phase, as well as between their square roots. An essential tool of independent interest is an equivariant version of the adjoint Polyakov-Wiegmann formula for fields $\mathbb{T}^2 \to U(N)$, of which we provide a proof employing only basic homotopy theory and circumventing the language of bundle gerbes.Comment: 23 pages, 1 figure. To appear in Letters in Mathematical Physic