101 research outputs found

    Predicting realistic and precise human body models under clothing based on orthogonal-view photos

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    6th International Conference on Applied Human Factors and Ergonomics (AHFE 2015) and the Affiliated Conferences, AHFE 2015, Las Vegas, USA, 26-30 Jul 20152015-2016 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    Garment patterns generating based on 3-D body scanning

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    2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Streptokinase is ineffective in restoring early myocardial reperfusion in Asian patients with acute myocardial infarction

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    Implementing Effective Group Work for Mathematical Achievement in Primary School Classrooms in Hong Kong

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    The Hong Kong Education Bureau recommends that primary school pupils’ mathematical achievement be enhanced via collaborative discussions engendered by group work. This pedagogic change may be hindered by Confucian heritage classroom practices and Western-dominated group work approaches that predominate in Hong Kong. To overcome these obstacles, we introduced a relational approach to group work in a quasi-experimental study. Our sample included 20 teachers randomly allocated to experimental (12) and control (8) conditions and their 504 mathematics pupils (aged 9–10). The relational approach focused on the development of peer relationships in a culturally appropriate manner and was implemented over 7 months. Pupils were pre-/post-tested for mathematical achievement and systematically observed, and the teachers were assessed for subject knowledge and pre-/post-tested for pedagogic efficacy. Analysis of covariance (ANCOVA) and hierarchical linear modeling (HLM) results show enhanced mathematical achievement, supported by improved peer-based communication skills and time-on-task for the experimental pupils. Experimental teachers raised their pedagogic efficacy. Results indicate the potential of the relational approach for boosting academic achievement via enhanced child-peer-teacher interaction and the need to reassess the role of peer-based latent collectivist learning in Confucian heritage classrooms.postprin

    Sex hormones and apoptosis and immunoglobulin production in systemic lupus erythematosus

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    BACKGROUND: SLE is an autoimmune disease that affects predominantly female of reproductive age. Previous studies have suggested an immunomodulatory role of sex hormones in the pathogenesis of SLE. Objectives: To examine the effects of various sex hormones on apoptosis and immunoglobulin production by peripheral blood mononuclear cells (PBMCs) in SLE patients …published_or_final_versio

    Effects of waist and lower limb movements on clothing ease design

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    2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Cervical dysplasia in patients with systemic lupus erythematosus

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    Highly pathogenic avian influenza H5N1 virus delays apoptotic responses via activation of STAT3

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    Highly pathogenic avian influenza (HPAI) H5N1 virus continues to pose pandemic threat, but there is a lack of understanding of its pathogenesis. We compared the apoptotic responses triggered by HPAI H5N1 and low pathogenic H1N1 viruses using physiologically relevant respiratory epithelial cells. We demonstrated that H5N1 viruses delayed apoptosis in primary human bronchial and alveolar epithelial cells (AECs) compared to H1N1 virus. Both caspase-8 and -9 were activated by H5N1 and H1N1 viruses in AECs, while H5N1 differentially up-regulated TRAIL. H5N1-induced apoptosis was reduced by TRAIL receptor silencing. More importantly, STAT3 knock-down increased apoptosis by H5N1 infection suggesting that H5N1 virus delays apoptosis through activation of STAT3. Taken together, we demonstrate that STAT3 is involved in H5N1-delayed apoptosis compared to H1N1. Since delay in apoptosis prolongs the duration of virus replication and production of pro-inflammatory cytokines and TRAIL from H5N1-infected cells, which contribute to orchestrate cytokine storm and tissue damage, our results suggest that STAT3 may play a previously unsuspected role in H5N1 pathogenesis.published_or_final_versio

    Quality of life (QoL) in southern Chinese with systemic lupus erythematosus (SLE)

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    Conference Theme: Challenges to specialists in the 21st centurypublished_or_final_versio
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