Effect of SNPs rs6921438 and rs10738760 on variation in quantitative traits related to T2D complications in type 2 diabetic participants from the Corbeil and Diab2-Néphrogène (D2NG) studies.

*<p>Per X-allele effect size: coefficient β from additive linear regression models adjusted for T2D duration and gender.</p><p>Data are presented as mean ± standard deviation or median (interquartile range). Data for ACR were logarithmically transformed before statistical analysis.</p><p><b><i>eGFR</i></b>, estimated glomerular filtration rate using modification of diet in renal disease (MDRD) formula; <b><i>ACR</i></b>, urinary albumin/creatinine ratio; <b><i>T2D</i></b>, type 2 diabetes; <b><i>SE</i></b>, standard error; <b><i>CI</i></b>, confidence interval; <b><i>P</i></b>, P-value.</p

Case numbers needed for reaching a statistical power of 80% according to the expected odds ratio or effect.

<p>Only statistical power of association analyses with a P-value above 0.05 was analysed.</p><p><b><i>β</i></b>, effect size; <b><i>OR</i></b>, odds ratio; <b><i>NA</i></b>, not applicable; <b><i>eGFR</i></b>, estimated glomerular filtration rate using modification of diet in renal disease (MDRD) formula; <b><i>ACR</i></b>, urinary albumin/creatinine ratio.</p

Association of SNPs rs6921438 and rs10738760 with T2D risk in two European case-control studies.

*<p>OR from additive logistic regression models adjusted for age and gender.</p><p><b><i>T2D</i></b>, type 2 diabetes; <b><i>OR</i></b>, odds ratio; <b><i>CI</i></b>, confidence interval; <b><i>P</i></b>, P-value.</p