Trade-off curves applications to support set-based design of a surface jet pump

Knowledge has become the most important asset of companies, especially in improving their product development processes. The set-based design approach is an efficient way of designing high quality, optimised designs. However, it requires a proven knowledge environment. Trade-off curves (ToCs) have the capability of providing the right knowledge and displaying it in a visual form. Although there are a few applications of ToCs that have recently been published in the literature, none of them demonstrates an integrated implementation of ToCs throughout the SBCE process. This paper presents the integrated use of ToCs, based on both physics-knowledge and proven knowledge, in order to compare and narrow down the design-set and to achieve an optimal design solution. These are key activities of the SBCE process model. Since an accurate, documented and visual knowledge environment is created by the use of ToCs within SBCE, the integrated approach proposed in this paper plays a vital role in eliminating the need for prototyping and testing at the early stages of product development. The integrated approach was implemented in an industrial case study for a surface jet pump. Surface jet pumps are used to increase the production rate of low-pressure oil/gas wells. It has been found that through ToCs, the conflicting relationships between the characteristics of the product can be understood and communicated effectively among the designers. This facilitated the decision-making on an optimal design solution in a remarkably short period of time. Furthermore, the surface jet pump resulting from the case study achieved an increase of the oil/gas production by nearly 60%

Set-based concurrent engineering process model and systematic application on an electronic card reader

Set-based concurrent engineering (SBCE), also known as set-based design, is a state-of-the-art approach to the new product development process. SBCE, simply, provides an environment where designers explore a wide range of alternative solutions in the early stages of product development. After gaining knowledge, solutions are narrowed down until the optimal solution is ensured. Such an environment saves considerable amount of cost and time while reaching innovation and high quality in the products. However, industrial practitioners seek a clear and systematic application throughout an SBCE process. This paper demonstrates a well-structured SBCE process model and its step-by-step application on a product called “electronic card reader”. Real data is used in the industrial case study. Results showed the benefits of applying SBCE in both the product, and the process of new product development

The set-based concurrent engineering application: a process of identifying the potential benefits in the surface jet pump case study

The Set-Based Concurrent Engineering (SBCE) is the methodology that can improve the efficiencies and effectiveness of product development. It is found that the SBCE approach provided a suitable knowledge environment to support decision making throughout the development process. This paper presents the potential tangible benefits gained from the application of the SBCE in an industrial case study of a Surface Jet Pump (SJP) that is used to revive the production of oil/gas from the dead wells. The well-structured SBCE process model and the process of identifying the potential benefits proposed in this paper will clarify the gap in the development of the SBCE in the company. The potential tangible benefits are established in a few key areas such as product innovation, product performance, manufacturing cost, and project success rate

Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research