8 research outputs found
Geographical locations of 18 laboratories with PCR, GeneXpert, and genetic sequencing capacity in Yemen by November 2022.
Geographical locations of 18 laboratories with PCR, GeneXpert, and genetic sequencing capacity in Yemen by November 2022.</p
Challenges encountered during the pandemic response in Yemen Challenges.
Challenges encountered during the pandemic response in Yemen Challenges.</p
Improvement in the molecular biology capacity in Yemen—Before and after the COVID-19 pandemic.
Improvement in the molecular biology capacity in Yemen—Before and after the COVID-19 pandemic.</p
Timelines highlighting important milestones on the evolution of virus in Yemen and period for the establishment of PCR and other laboratories.
Timelines highlighting important milestones on the evolution of virus in Yemen and period for the establishment of PCR and other laboratories.</p
Performance of two national-level laboratories in external quality assessment scheme.
Performance of two national-level laboratories in external quality assessment scheme.</p
Location and volumes of PCR testing performed for surveillance purpose (orange colour) and for travelers (blue) in Yemen by December 2022.
More testing happened in the southern governorates of the country where points of entry (POEs) are located, noting no positive COVID-19 cases were formally reported from the northern governorates.</p
S1 Dataset -
BackgroundWhen the COVID-19 pandemic was declared, Yemen, a country facing years of conflict had only one laboratory with PCR testing capacity. In this article, we describe the outcome of the implementation of molecular based diagnostics platform in Yemen and highlight the key milestones the country went through to increase access to testing for its populations residing in a geographically vast and politically divided country.MethodsA retrospective assessment of COVID-19 laboratory response activities was done detailing the needs assessment process, timelines, geographical coverage, and outcomes of the activities. Laboratory data was analyzed to construct the geographical locations of COVID-19 testing laboratories and the numbers of tests performed in each facility to highlight the demands of testing for travelers. Finally, we discuss the impact these activities had in enabling the movement of people across international borders for economic gains and in delivery of critical humanitarian aid.OutcomePCR testing capacities in Yemen significantly improved, from one laboratory in Sanaa in April 2020 to 18 facilities across the country by June 2022. In addition, the number of functional Real-Time PCR thermocyclers increased from one to 32, the PCR tests output per day improved from 192 to 6144 tests per day. Results from analysis of laboratory data showed there were four peaks of COVID-19 in Yemen as October 2022. The majority of laboratory tests were performed for travelers than for medical or public health reasons. Demand for laboratory testing in Yemen was generally low and waned over time as the perceived risk of COVID-19 declined, in parallel with rollout of the COVID-19 vaccines.Discussion/ConclusionThe successful expansion of laboratory testing capacity was instrumental in the control and management of COVID-19 cases and critical in the implementation of public response strategies, including restrictions on gathering. Laboratory testing also facilitated the movement of humanitarian agencies and delivery of aid and enabled hundreds of thousands of Yemeni nationals to travel internationally. By virtue of these outcomes, the impact of laboratory strengthening activities was thus felt in the health sector and beyond.</div
Temporal patterns of SARS-COV-2 samples analyzed for the purposes of surveillance in Yemen from April 2020 to December 2022.
Temporal patterns of SARS-COV-2 samples analyzed for the purposes of surveillance in Yemen from April 2020 to December 2022.</p