An extensive category III oedematous lesion involving the anterior and posterior chest and neck regions, with two ulcers: one at the anterior triangle of the neck, measuring 6 cm x 8 cm, and another over the midsternal region of the chest, measuring 3 cm x 4 cm.

<p>An extensive category III oedematous lesion involving the anterior and posterior chest and neck regions, with two ulcers: one at the anterior triangle of the neck, measuring 6 cm x 8 cm, and another over the midsternal region of the chest, measuring 3 cm x 4 cm.</p

Chest radiographs of patient before and during antibiotic chemotherapy for <i>M. ulcerans</i> disease.

<p>(A) Chest X-ray taken before antibiotic therapy was started. (B) Chest X-ray taken 2 weeks after initiation of antibiotic therapy, showing bilateral pleural effusions. (C) Week 3 after drainage of pleural effusion. (D) Recurrence of pleural effusion on the right hemithorax at week 4.</p