Non-essential metals (Cd & Pb) accumulation and elimination in liver tissue of juvenile milkfish, after sublethal exposure

412-417Present study consists the bioaccumulation of cadmium and lead in young juvenile Milkfish liver (Chanos chanos). It is carried out after exposure to three sublethal concentration of each pollutants (on 1/20, 1/10 and 1/5 LC50 of 96-h LC50) for acute time 12, 24 and 96 hour and subchronic time 7, 14 and 21 days. Cadmium and lead accumulation in liver increased with exposure periods and concentration of pollutants. Compared with controls, the uptake of cadmium is much higher than that of lead. Accumulation factors showed an increase with the exposure period and an inverse relationship between the accumulation factor and exposure concentration for lead. Elimination of these two pollutants was investigated after 30 days depuration time. During the depuration phase, cadmium and lead concentration decreased