12,832 research outputs found
Nucleon-Nucleon Scattering in a Strong External Magnetic Field and the Neutrino Emissivity
The nucleon-nucleon scattering in a large magnetic background is considered
to find its potential to change the neutrino emissivity of the neutron stars.
For this purpose we consider the one-pion-exchange approximation to find the NN
cross-section in a background field as large as
. We show that the NN cross-section in
neutron stars with temperatures in the range 0.1-5 \texttt{MeV} can be changed
up to the one order of magnitude with respect to the one in the absence of the
magnetic field. In the limit of the soft neutrino emission the neutrino
emissivity can be written in terms of the NN scattering amplitude therefore the
large magnetic fields can dramatically change the neutrino emissivity of the
neutron stars as well.Comment: 21 pages, 5 figures, to appear in PR
Cephalometric norms for the upper airway in a healthy Hong Kong Chinese population
Objective. To obtain normative data for cephalometric measurements of the upper airway in the local Chinese population. Design. Observational study. Setting. University department and teaching hospital out-patient clinic. Subjects and methods. Subjects included 74 healthy patients, 29 males (age range, 18-35 years) and 45 females (age range, 16-42 years), with normal skeletal facial profile, no history of snoring, sleep apnoea, upper airway disease, tonsillectomy or adenoidectomy, obesity, of pathology in the pharynx. Twenty cephalometric airway measurements, including size of the tongue, soft palate, nasopharynx, oropharynx, hypopharynx, and relative position of the hyoid bone and valleculae were obtained. Landmarks on cephalometric radiographs were digitised and measurements were made using a specially designed computer programme. Error analysis of measurements was performed and comparison of measurements according to sex was made. Results. Significant sex dimorphism was seen for the majority of measurements, with the exception of minimal depth of the airway, oropharyngeal depth of the airway, and the soft palate angle with the hard palate. Conclusion. A minimum sagittal dimension of the upper airway was evident despite differences in measurements between sexes. Findings from this study should be a useful reference for the assessment of sleep apnoea in the local population.published_or_final_versio
Dynamic models of viral replication and latency.
PURPOSE OF REVIEW: HIV targets primary CD4(+) T cells. The virus depends on the physiological state of its target cells for efficient replication, and, in turn, viral infection perturbs the cellular state significantly. Identifying the virus-host interactions that drive these dynamic changes is important for a better understanding of viral pathogenesis and persistence. The present review focuses on experimental and computational approaches to study the dynamics of viral replication and latency.
RECENT FINDINGS: It was recently shown that only a fraction of the inducible latently infected reservoirs are successfully induced upon stimulation in ex-vivo models while additional rounds of stimulation make allowance for reactivation of more latently infected cells. This highlights the potential role of treatment duration and timing as important factors for successful reactivation of latently infected cells. The dynamics of HIV productive infection and latency have been investigated using transcriptome and proteome data. The cellular activation state has shown to be a major determinant of viral reactivation success. Mathematical models of latency have been used to explore the dynamics of the latent viral reservoir decay.
SUMMARY: Timing is an important component of biological interactions. Temporal analyses covering aspects of viral life cycle are essential for gathering a comprehensive picture of HIV interaction with the host cell and untangling the complexity of latency. Understanding the dynamic changes tipping the balance between success and failure of HIV particle production might be key to eradicate the viral reservoir
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