Simultaneous Kinetic Spectrophotometric Determination of Hydrazine and Isoniazid Using H-Point Standard Addition Method and Partial Least Squares Regression in Micellar Media

The present study describes the application of simultaneous kinetic spectrophotometric determination of hydrazine (HZ) and isoniazid (INH), using H-point standard addition method (HPSAM) and partial least squares (PLS) calibration. The methods are based on the difference observed in the rate of iron (III) reduction with HZ and INH, in the presence of 2,2\u27-bipyridine (Bpy) and the subsequent complex formation between the resulted Fe2+ and Bpy in a solution containing sodium dodecyl sulfate (SDS) as a micellar medium. INH and HZ can simultaneously be determined between the range of 0.08−6.0 and 1.0−80.0 μg mL−1, respectively. The results have shown that by the application of HPSAM, the simultaneous determination could be performed with the ratio of 1:1000 to 1:12.5 for INH-HZ. Through the HPSAM analysis, the relative standard deviations of HZ and INH were 2.5 and 1.2, respectively. The total relative standard error for applying the PLS method to 9 synthetic samples, in the concentration ranges of 0.0−20.0 μg mL−1 of HZ and 0.5−3.0 μg mL−1 of INH, was 3.19. Both proposed methods (PLS and HPSAM) were successfully applied to the simultaneous determination of HZ and INH in several commercially available isoniazid formulations and satisfactory results were obtained.</p

Evaluation of the influences of various force magnitudes and configurations on scoliotic curve correction using finite element analysis

Scoliosis is a lateral curvature in the normally straight vertical line of the spine, and the curvature can be moderate to severe. Different treatment can be used based on severity and age of subjects, but most common treatment for this disease is using orthosis. To design orthosis types of force arrangement can be varied, from transverse loads to vertical loads or combination of them. But it is not well introduced how orthoses control scoliotic curve and how to achieve the maximum correction based on force configurations and magnitude. Therefore, it was aimed to determine the effect of various loads configurations and magnitudes on curve correction of a degenerative scoliotic subject. A scoliotic subject participated in this study. The CT-Scan of the subject was used to produce 3D model of spine. The 3D model of spine was produced by Mimics software and the finite element analysis and deformation of scoliotic curve of the spine under seven different forces and in three different conditions was determined by ABAQUS software. The Cobb angle in scoliosis curve decreased significantly by applying forces. In each condition depends on different forces, different corrections have been achieved. It can be concluded that the configurations of the force application mentioned in this study is effective to decrease the scoliosis curve. Although it is a case study, it can be used for a vast number of subjects to predict the correction of scoliosis curve before orthotic treatment. Moreover, it is recommended that this method and the outputs can be compared with clinical findings

Evaluation of the magnitude of hip joint deformation in subjects with avascular necrosis of the hip joint during walking with and without Scottish Rite orthosis

The femoral head in subjects with leg calve perthes disease (LCPD) is generally considerably deformed. It is debatable whether this deformation is due to an increase in applied loads, a decrease in bone mineral density or a change in containment of articular surfaces. The aim of this study was to determine the influence of these factors on deformation of the femoral head. Two subjects with LCPD participated in this study. Subject motion and the forces applied on the affected leg were recorded using a motion analysis system (QualsisTM) and a Kistler force plate. OpenSim software was used to determine joint contact force of the hip joint whilst walking with and without a Scottish rite orthosis. 3D Models of hip joints of both subjects were produced by Mimics software. The deformation of femoral bone was determined by Abaqus. Mean values of the force applied on the leg increased while walking with the orthosis. There was no difference between bone mineral density (BMD) of the femoral bone of normal and LCPD sides (p-value>0.05) and no difference between hip joint contact force of normal and LCPD sides. Hip joint containment appeared to decrease follow the use of the orthosis. It can be concluded that the deformation of femoral head in LCPD may not be due to change in BMD or applied load. Although the Scottish rite orthosis is used mostly to increase hip joint containment, it appears to reduce hip joint contact area. It is recommended that a similar study is conducted using a higher number of subjects

Experimental Investigation of Interfacial Tension Measurement and Oil Recovery by Carbonated Water Injection : A Case Study Using Core Samples from an Iranian Carbonate Oil Reservoir

The authors would like to gratefully acknowledge and appreciate the Department of Petroleum Engineering, Faculty of Engineering, Marvdasht Islamic Azad University, Marvdasht, 73711-13119, Iran, for the provision of the laboratory facilities necessary for completing this work.Peer reviewedPostprin

Related factors of physical activity preventive behavior of osteoporosis based on health belief model among teen girls in Qom City, Iran

Background Although osteoporosis is a disease of adulthood, it can start from childhood and adolescence. Lifestyle, especially physical activity, mobility, and proper nutrition during adolescence are among the important osteoporosis preventive factors. Therefore, this study aimed to determine related factors of physical activity preventive behavior of osteoporosis based on the Health Belief Model (HBM) among teen girls in Qom city, Iran. Materials and Methods This cross-sectional descriptive analytical study was conducted on 265 tenth to twelfth grade girl students in Qom city. The participants were selected via multistage sampling method. A researcher-made questionnaire based on Health Belief Model used for data collection. Data were analyzed using SPSS-20. Results The current study, knowledge and perceived self-efficacy had a significant and positive relationship with physical activity behavior (r=0.13, P 0.05). Conclusion The results of the study showed that educational interventions and programs must focus on increasing knowledge and perceived self-efficacy to enhance physical activity behavior and reduce the perceived barriers associated with osteoporosis preventive physical activity

RELATION BETWEEN ANTHROPOMETRIC DATA AND PERFORMANCE OF LOWER LIMB IN SQUAT JUMP

In this study, the total peak of joints’ torque, work, and the maximum jump height were measured in ten physically active male subjects performing the squat jump (SJ), and squat jump with arm swing (SJA). Accordingly, arm swing caused an increment in the heights of squat jump (p\u3c0.001).The results revealed relationships between body mass and height with the total peak of joints’ torque (0.5

Ensembles of Random Projections for Nonlinear Dimensionality Reduction

Dimensionality reduction methods are widely used in informationprocessing systems to better understand the underlying structuresof datasets, and to improve the efficiency of algorithms for bigdata applications. Methods such as linear random projections haveproven to be simple and highly efficient in this regard, however,there is limited theoretical and experimental analysis for nonlinearrandom projections. In this study, we review the theoretical frameworkfor random projections and nonlinear rectified random projections,and introduce ensemble of nonlinear maximum random projections.We empirically evaluate the embedding performance on 3commonly used natural datasets and compare with linear randomprojections and traditional techniques such as PCA, highlightingthe superior generalization performance and stable embedding ofthe proposed method

Identification and analysis of IoT applications in the fight against and control of epidemic diseases (Case study: Covid 19 disease)

IoT technology offers many benefits in health care and epidemic control and will greatly facilitate the process of continuous remote patient diagnosis and monitoring with wireless sensors and smart devices. This article aims to identify and analyze the applications of the Internet of Things to combat and control epidemics such as covid 19 disease. This research was applied in terms of purpose, which was conducted in two stages. First, by reviewing the theoretical foundations and previous studies through the method of reviewing texts, IoT applications in combating and controlling epidemic diseases such as covid 19 disease were identified; then, to confirm and prioritize the identified applications, these applications were provided to 23 experts from academic experts and experts in the medical field. IoT applications in the fight against and control of epidemic diseases such as covid 19, It has the dimensions of therapeutic applications (5 components and 9 indicators), Monitoring applications (4 components and 14 indicators), Information applications (2 components and 5 indicators), management applications (2 components and 8 indicators), prevention applications (7 components and 14 indicators). In the case of epidemics such as covid19 disease, The Internet of Things improves the quality of treatment and diagnosis, supports decision-making and monitoring patients 'vital signs, reduces hospital visits, and increases the ability to monitor and monitor patients' condition

Simultaneous Kinetic Spectrophotometric Determination of Hydrazine and Isoniazid Using H-Point Standard Addition Method and Partial Least Squares Regression in Micellar Media

The present study describes the application of simultaneous kinetic spectrophotometric determination of hydrazine (HZ) and isoniazid (INH), using H-point standard addition method (HPSAM) and partial least squares (PLS) calibration. The methods are based on the difference observed in the rate of iron (III) reduction with HZ and INH, in the presence of 2,2\u27-bipyridine (Bpy) and the subsequent complex formation between the resulted Fe2+ and Bpy in a solution containing sodium dodecyl sulfate (SDS) as a micellar medium. INH and HZ can simultaneously be determined between the range of 0.08−6.0 and 1.0−80.0 μg mL−1, respectively. The results have shown that by the application of HPSAM, the simultaneous determination could be performed with the ratio of 1:1000 to 1:12.5 for INH-HZ. Through the HPSAM analysis, the relative standard deviations of HZ and INH were 2.5 and 1.2, respectively. The total relative standard error for applying the PLS method to 9 synthetic samples, in the concentration ranges of 0.0−20.0 μg mL−1 of HZ and 0.5−3.0 μg mL−1 of INH, was 3.19. Both proposed methods (PLS and HPSAM) were successfully applied to the simultaneous determination of HZ and INH in several commercially available isoniazid formulations and satisfactory results were obtained.</p