Accurate Design of Arbitrary Anisotropy in Multilayer Microwave Circuits.

This paper deals with the hybrid-mode analysis of anisotropic microwave circuits with an arbitrary polarization of the optical axis. Based on the spectral domain approach (SDA), the proposed technique takes into account the multilayer aspect of these circuits. A set of well-behaved basis functions were chosen to expand the current density on the strips. Galerkin’s method was used to find the propagation constant and other dispersion characteristics. Numerical results are in good agreement with data available in the literature

A Novel FDTD Algorithm for Analyzing Microwave Filters with Imperfectly Conductors

In this paper, we propose a new FDTD algorithm to design microwave filters with imperfectly conductors. For this purpose, we have developed a mesh function to describe the thin film material. Then, we have applied our algorithm for the analysis of a microwave resonator performance. The effects of finite conductivity and thin film thickness have also been investigated. Computed results are in good agreement with simulated data using CST electromagnetic tool

Design of Multiband-Filters for Mobile Radio Applications

In this paper, a new multi-standard filter with four resonance frequencies is proposed for radio-mobile including GSM/4G LTE, WLAN and 5 G applications. The design and synthesis is resolved using a new formulation of the FDTD method. The metal finite conductivity and thickness are rigorously taken into account. The FDTD computed results are in good agreement with simulated data obtained with CST electromagnetic tool

An Enhanced FDTD Algorithm for Multilayer Waveguides and Filters

In this paper, a new formulation of the finite difference time domain technique was applied for efficient hybrid-mode analysis of inhomogeneous planar waveguides and filters. An enhanced analytical formula for the cut-off frequency was also proposed for a three-layer waveguide while the shielding effect was investigated on band-pass filter performance. The computed S-parameters are in good agreement with simulated ones obtained with the CST electromagnetic tool

A Rare MSH2 Variant as a Candidate Marker for Lynch Syndrome II Screening in Tunisia: A Case of Diffuse Gastric Carcinoma

Several syndromic forms of digestive cancers are known to predispose to early-onset gastric tumors such as Hereditary Diffuse Gastric Cancer (HDGC) and Lynch Syndrome (LS). LSII is an extracolonic cancer syndrome characterized by a tumor spectrum including gastric cancer (GC). In the current work, our main aim was to identify the mutational spectrum underlying the genetic predisposition to diffuse gastric tumors occurring in a Tunisian family suspected of both HDGC and LS II syndromes. We selected the index case “JI-021”, which was a woman diagnosed with a Diffuse Gastric Carcinoma and fulfilling the international guidelines for both HDGC and LSII syndromes. For DNA repair, a custom panel targeting 87 candidate genes recovering the four DNA repair pathways was used. Structural bioinformatics analysis was conducted to predict the effect of the revealed variants on the functional properties of the proteins. DNA repair genes panel screening identified two variants: a rare MSH2 c.728G>A classified as a variant with uncertain significance (VUS) and a novel FANCD2 variant c.1879G>T. The structural prediction model of the MSH2 variant and electrostatic potential calculation showed for the first time that MSH2 c.728G>A is likely pathogenic and is involved in the MSH2-MLH1 complex stability. It appears to affect the MSH2-MLH1 complex as well as DNA-complex stability. The c.1879G>T FANCD2 variant was predicted to destabilize the protein structure. Our results showed that the MSH2 p.R243Q variant is likely pathogenic and is involved in the MSH2-MLH1 complex stability, and molecular modeling analysis highlights a putative impact on the binding with MLH1 by disrupting the electrostatic potential, suggesting the revision of its status from VUS to likely pathogenic. This variant seems to be a shared variant in the Mediterranean region. These findings emphasize the importance of testing DNA repair genes for patients diagnosed with diffuse GC with suspicion of LSII and colorectal cancer allowing better clinical surveillance for more personalized medicine

Abstracts of the First International Conference on Advances in Electrical and Computer Engineering 2023

This book presents extended abstracts of the selected contributions to the First International Conference on Advances in Electrical and Computer Engineering (ICAECE'2023), held on 15-16 May 2023 by the Faculty of Science and Technology, Department of Electrical Engineering, University of Echahid Cheikh Larbi Tebessi, Tebessa-Algeria. ICAECE'2023 was delivered in-person and virtually and was open for researchers, engineers, academics, and industrial professionals from around the world interested in new trends and advances in current topics of Electrical and Computer Engineering. Conference Title: First International Conference on Advances in Electrical and Computer Engineering 2023Conference Acronym: ICAECE'2023Conference Date: 15-16 May 2023Conference Venue: University of Echahid Cheikh Larbi Tebessi, Tebessa-AlgeriaConference Organizer: Faculty of Science and Technology, Department of Electrical Engineering, University of Echahid Cheikh Larbi Tebessi, Tebessa-Algeri