Anatomic variations of intrahepatic bile ducts in the general adult Egyptian population: 3.0-T MR cholangiography and clinical importance

AbstractObjectiveTo describe the anatomical variations occurring in intrahepatic bile ducts (IHDs) and their frequencies in general adult Egyptian population using 3.0-T MR cholangiography (MRC) as well as its clinical importance to reduce the biliary complications of hepatobiliary surgery.Materials and methodsMRC was applied to a study group of 106 subjects (26 potential liver donors and 80 volunteers). Anatomical variations in IHDs were classified based on the variable insertion of right posterior hepatic bile duct (RPHD) using Huang classification.ResultsAccording to this classification, the frequencies of each type were as follows: Huang A1 (typical pattern): 63.2% (n=67), Huang A2: 10.4% (n=11), Huang A3: 17% (n=18), Huang A4, 7.5% (n=8), and Huang A5: 1.9% (n=2). Total frequency for atypical types (i.e. A2, A3, A4 and A5) was 36.8%. No significant difference was detected in the distance between RPHD insertion to the junction of right and left hepatic duct in-between these Huang types. This distance was short (<1cm) in 21 of subjects under Huang A classification. Twenty-one donors underwent intraoperative cholangiograms, of which twenty (95.2%) had similar classification in both intraoperative and MRC findings.ConclusionThe incidence of variant biliary anatomy in general Egyptian population (36.8%) as well as the presence of Huang type A with short distance (<1cm) between RPHD insertion and junction of right and left hepatic duct (19.8%) enhance the importance of MRC as a pre-operative tool before hepato-biliary surgical procedures to reduce post-operative biliary complications

LISTERIA MONOCYTOGENESIN RAW MILK AND DAIRY PRODUCTS;OCCURRENCE AND TRIALS FOR THEREDUCTION OF THEIR RESISTANCE TO ANTIBIOTICS.

Listeria monocytogenes is a facultative intracellular pathogen responsible for severe infection in animals and humans. This study aimed to determine the occurrence of Listeriamonocytogenes in 200 samples of raw milk and dairy products marketed in Egypt, with detection the antimicrobial resistance profiles of the isolates for different antimicrobial agents. The synergistic effects of three plant extracts in combination with the used antimicrobials to control resistant L. monocytogenes isolates were assessed, with evaluation of relationship between the antibacterial activity and composition of plant extracts. A total of 5 (2.5%) L. monocytogenes isolates were identified (3 isolates from raw milk and two isolates from kariesh cheese and ice cream, one each). The isolates were sensitive to ciprofloxacin and sulphadimidine, while for amoxicillin and oxytetracycline, were resistant. The higher antimicrobial effects of basil and cinnamon extracts were detected, in addition, low concentrations of them were enough to show synergistic effect with the amoxicillin and oxytetracycline to control resistant isolates, these might be attributable to their chemical compositions. In conclusion, there is need for effectively pasteurized raw milk consumption or usage in the production of dairy products. In addition, the chemical composition of these plant extracts might help in its use to control resistant isolates with appropriate antibiotics without the need for increasing the used dosage doses

Effect of Quercetin on Diabetic Rat

Background: Quercetin (QR) is one of the major constituents of the methanolic extract of the leaves of Psidium guajava (Guava leaves). Objectives: The work’s aim is to understand the Quercetin’s mechanism in improving insulin resistance, use the homeostasis model assessment for insulin resistance (HOMA-IR) to determine the influence of quercetin on glycemic control, Look at how quercetin affects diabetes-related lipid metabolism and lipid profile measures. Analyze the impact of QR on oxidative stress in diabetic rats and contrast its antidiabetic effects whether administered as a nutrient or supplement. Materials and methods: Sixty adult male Wister rats that were matched in age and had starting body weights between 150 and 200 g were used in this study. One normoglycemic control group and 3 diabetic control groups (15 rats per group) were used. The diabetic control rats received the vehicle orally as saline daily, the normoglycemic control group received quercetin orally in a dose of 50 mg/kg per day, and the diabetic rats received quercetin orally in a dose of 100 mg/kg per day. Results: After six weeks of therapy, the rats with diabetes receiving isolated quercetin at doses of 50 and 100 mg/kg had reduced blood glucose levels, and their triglyceride, low-density lipoprotein, and total cholesterol profiles all significantly improved. Also, there was significant decrease homeostatic model assessment for insulin resistance, serum transaminases, hepatic malondialdehyde, and HMG CoA expression in liver and a substantial rise in levels of insulin, hepatic GSH, and insulin receptor substrate (IRS2) expression & Phosphoinositide 3-kinases in liver as compared to those of control group, but non- significance changes in high-density lipoprotein, AKT expression in liver were observed. Conclusions: Quercetin could be considered as a potential hypoglycmeic medication with possible mechanisms controlling the hyperglycemic state and cholesterol, triglycerides and LDL levels

Lactation performance and feed utilization of Rahmani ewes fed with either a newly produced bacteriocin-like substance or a commercial bacteriocin

The aim of the present study was to compare the effect of feeding a newly produced bacteriocin-like substance from Lactococcus lactis ssp. lactis (PNP) with a commercial bacteriocin (NISEEN-S; CNP) in lactating Rahmani ewe diets. In experiment 1, the effects of four levels (500, 1,000, 1,500, and 2,000 unit/kg substrate, dry matter (DM) basis) of both bacteriocins on in vitro ruminal fermentation kinetics, total gas production (TGP), methane production (CH4), and nutrient degradability were determined. In experiment 2, 2 wk before the expected parturition, 30 multiparous lactating Rahmani ewes (mean ± SD: 2 ± 0.3 parity, 46.8 ± 2.5 kg body weight, 23 ± 2.7 mo of age, and 370 ± 13 g/d of previous milk production) were equally divided into three treatments in a complete randomized design for 90 d. The ewes in the control treatment were offered a diet composed of 600 g of concentrate feed mixture, 300 g berseem hay, and 100 g of faba bean straw (Control), or supplemented with produced bacteriocin like substance (PNP) or commercial (CNP) bacteriocin at 500 unit/kg feed (DM basis). In experiment 1, both PNP and CNP linearly and quadratically decreased (P < 0.001) CH4 production; however, PNP and CNP at 500 unit/kg feed quadratically increased fiber degradability (P < 0.01). In experiment 2, both PNP and CNP increased (P < 0.05) nutrient digestibility, and ruminal total volatile fatty acids, acetate, and propionate, while decreasing ruminal ammonia-N. The PNP treatment increased (P < 0.05) blood total proteins and albumin, while PNP and CNP treatments increase serum glucose. Both PNP and CNP treatments increased (P < 0.05) daily milk production and milk efficiency, without affecting the concentration of milk components. Both PNP and CNP are recommended to improve feed utilization and milk production, with superior results detected for PNP at 500 unit/kg feed daily

Role of prostatic artery embolization in management of symptomatic benign prostatic hyperplasia

AbstractObjectivesTo assess the feasibility and efficacy of prostatic artery embolization in relieving symptoms of benign prostatic hyperplasia.Materials and methodsIn a prospective study 28 patients with symptomatic benign prostatic hyperplasia were presented for prostatic artery embolization between June 2012 and June 2014. Patients age was 48–85years with mean age 68.5years±10.6SD. International Prostate Symptoms Score (IPSS) before intervention measured 20–35 with mean score 26.3±6.8SD. Prostatic volume before intervention ranged between 48 and 166cc3 with mean of 82.6±11.2SD.ResultsTechnical success was achieved in all cases (100%). All patients were followed for 6months after the procedure. IPSS improved at 6months in all patients with post embolization mean of 12.2±3.4SD with significant P value of 0.0006. Mean post-procedure prostatic volume at 6months was 49.8cc3±16.9SD with 39.7% mean volume reduction. No major complications were recorded. We achieved clinical success in 27 patients (96.4%) with only one non responding patient (3.6%).ConclusionProstatic artery embolization is a feasible technique and preliminary short-term results show promising high technical and clinical success rates in symptomatic patients with benign prostatic hyperplasia

Effect of canal width contraction on the hydraulic parameters and scour downstream water structures

The dimensions of many water streams, which satisfy proper hydraulic conditions, may not be compatible with the designed dimensions of an irrigation work that needs to be constructed in some locations. The design requirements of such irrigation works may involve a contraction in the channel width in the required location. This contraction, of course, affects different flow properties and the scour hole formed downstream of these structures. Therefore, the present experimental study aims to investigate the effect of the transition angle and the contraction on the flow properties and on the scour phenomenon downstream water structures. Through 460 experimental runs, carried out on 20 experimental models, the study proved that, for an efficient hydraulic performance and economic design, the best transition angle (θ) for the approaches of water structures is 30° with a relative contracted width ratio (r = b/B) not less than 0.6

Transboundary water resources “A comparative study”: The lessons learnt to help solve the Nile basin water conflict

The problematic water situation in Egypt, as one of the River Nile basin countries, has been heightened by the harmful effects of the Grand Ethiopian Renaissance Dam (GERD) on Egypt’s share of the Nile water. In the light of this Egyptian attention was directed towards a study of worldwide transboundary water problems, in order to find the most effective methods for dealing successfully with water shortage problems in basin countries. The present study focuses on the most successful experiences in the management and development of international river basins worldwide, as well as studying the possibility of implementing these experiences in other basins, especially the River Nile basin. The study showed that overcoming the water scarcity problems in Egypt and increasing the Nile water yield for all the basin countries can be achieved, first of all through serious cooperation among all the basin countries for minimizing the huge water losses from the river (more than 1480 Billion Cubic Metres per year which represents roughly 90% of the whole basin income), and secondly to make use of the most successful technical and political experiences that have been implemented in other international river basins mentioned in the present study

New technique for preparing and reusing agricultural drainage water safely in irrigation

Not so long ago, due to the great shortage of irrigation water, Egypt on the national level, began to mix (in a certain percentage) raw agricultural drainage water with fresh irrigation water. This mix was for enhancing its quality to be compatible with the proper specifications and standards of irrigation water, for using it safely in the irrigation process, to compensate for the severe shortage of available quantities of irrigation water. In some regions, and local farms, to save their crops farmers were forced to use the drainage water available in the nearby area drains for irrigation due to the problem of insufficient water in the distributary canals. Such use of raw drainage water can cause great harm and has a negative impact on the environment generally, especially on aquatic and agricultural life. Therefore, in this study we aim to introduce an efficient, simple, cheap mobile treatment unit. This new introduced treatment unit can be used locally on farms to solve the problem of insufficient quantities of irrigation water, and also in some cases where the irrigation water, for various reasons, does not reach the ends of some irrigation canals thus causing a serious problem for farmers. The new introduced treatment unit, using some environmentally friendly cheap materials in certain tested quantities and doses, through three designed cylindrical filtration containers connected with each other respectively, succeeded in converting raw contaminated drainage agricultural water into safe water that can be safely and directly used in the irrigation process

Effect of canal width contraction on the hydraulic parameters and scour downstream water structures

The dimensions of many water streams, which satisfy the proper hydraulic condition, may not be compatible with the designed dimensions of an irrigation work needed to be constructed in some locations. The design requirements of such irrigation works may need to make a contraction in the channel width in the location of constructions. This contraction, of course, affects the different flow properties and the scour hole formed downstream these structures. So, the present experimental study aims to investigate the effect of the transition angle and the contraction ratio on the flow properties and on the scour phenomenon downstream water structures. Through 454 experimental runs, carried out on 20 experimental models, the study proved that, for an efficient hydraulic performance and economic design, the best transition angle (θ) for the approaches of water structures is 30° with a contraction ratio (r) not less than 0.6. Keywords: Contraction ratio, Transition angle, Specific energy, Hydraulic parameters, Scou

Protective Impact of Chitosan Film Loaded Oregano and Thyme Essential Oil on the Microbial Profile and Quality Attributes of Beef Meat

Edible films and essential oil (EO) systems have the potency to enhance the microbial quality and shelf life of food. This investigation aimed to evaluate the efficacy of chitosan films including essential oils against spoilage bacteria and foodborne pathogens associated with meat. Antimicrobial activity (in vitro and in vivo) of chitosan films (CH) incorporated with oregano oil (OO) and thyme oil (TO) at 0.5 and 1% was done against spoilage bacteria and foodborne pathogens, compared to the control sample and CH alone. Preliminary experiments (in vitro) showed that the 1% OO and TO were more active against Staphylococcus aureus compared to Escherichia coli O157:H7 and Salmonella Typhimurium. In in vivo studies, CH containing OO and TO effectively inhibited the three foodborne pathogens and spoilage bacteria linked with packed beef meat which was kept at 4 °C/30 days compared to the control. The total phenolic content of the EOs was 201.52 mg GAE L−1 in thyme and 187.64 mg GAE L−1 in oregano. The antioxidant activity of thyme oil was higher than oregano oil. The results demonstrated that the shelf life of meat including CH with EOs was prolonged ~10 days compared to CH alone. Additionally, CH-OO and CH-TO have improved the sensory acceptability until 25 days, compared to the control. Results revealed that edible films made of chitosan and containing EOs improved the quality parameters and safety attributes of refrigerated or fresh meat