Comparison of serum fructosamine and HbA1c as an index of postprandial glycaemic control in diabetic patients

Kawalan paras glukosa dalam darah selepas makan adalah penting untuk mengelakkan komplikasi mikro dan makrovaskular, mengurangkan rintangan terhadap fungsi insulin, memulihkan rembesan hormon insulin, dan mengelakkan komplikasi kepada bayi yang akan dilahirkan oleh wanita yang mengidap penyakit diabetes. Kedua-dua pendekatan rawatan iaitu; pengurangan paras glukosa semasa berpuasa dan pengurangan paras glukosa selepas makan adalah berperanan dalam strategi rawatan diabetes. Rawatan yang memberikan penekanan kepada pengawalan paras glukosa selepas makan dikaitkan dengan pengawalan paras glukosa secara keseluruhan yang lebih baik. Langkah ini mengurangkan kejadian komplikasi kronik pada individu yang mengalami masalah diabetes dan gangguan toleransi glukos. Oleh itu suatu kaedah ukuran yang dapat mencerminkan paras glukosa selepas makan yangjitu perlu digunakan. Postprandial glycaemic control is important in avoiding microvascular and macrovascular complications, lowering insulin resistance, restoring normal insulin secretion, and avoiding complications in the offsprings of women with diabetes. It is recommended that the treatment of diabetes include methods that lower both fasting and postprandial glucose levels. Treatment aimed at controlling postprandial glucose levels is always associated with better overall glucose control and thus may result in fewer chronic complications in individuals with diabetes and impaired glucose tolerance. In order to achieve good postprandial glycemic control, a proper monitoring tool that represents postprandial glycaemia status should be used

Lipid Profile Parameters in Malaysian Dyslipidemic Patients

The importance of serum lipids as cardiovascular risk factors is well recognized. However, most published studies have focused on western countries. The present study aimed to describe and analyze the lipid profile parameters in Malaysian dyslipidemic patients, and to identify concomitant clinical problems and risk factors associated with cardiovascular disease (CVD) among such patients. Methods: A retrospective record review was carried out at Hospital Universiti Sains Malaysia.The records were reviewed for 890 dyslipidemic patients who attended the hospital in 2007. Data were collected for age at time of presentation, sex, ethnicity, smoking status, pre-treatment lipid levels, and presence of associated illnesses. The study sample was classified according to the National Cholesterol Education Program Adult Treatment Panel III risk groups. Results: The mean (SD) values for total cholesterol, low-density lipoprotein cholesterol, high density lipoprotein cholesterol, and triglycerides were 6.4 (1.3), 4.1 (1.3), 1.4 (0.5) and 1.9 (1.2) mmol/l, respectively. Less than half of study sample (43.1%) had coronary heart disease and coronary heart diseases equivalents, 24.3% were at moderate risk, and 32.6% were at low risk. Hypertension was present in 79.9% of the study sample, while 27.5% were diabetics. Cardiovascular disease was reported among 17.9%. Logistic regression revealed that family history of premature cardiovascular disease, higher age risk group; ethnicity and total cholesterol were predictors for the development of cardiovascular disease. Conclusion: The present review showed that dyslipidemic patients had high total cholesterol levels, according to National Cholesterol Education Program Adult Treatment Panel III guidelines. They were clinically diagnosed at middle age. Hypertension and diabetes were the commonest associated clinical problems. A large proportion of the patients were within the coronary heart disease or coronary heart disease risk equivalent group. Family history of premature cardiovascular disease, age, ethnicity, and total cholesterol are important risk factors for the development of cardiovascular disease in Malaysian dyslipidemic patients

Yusof Z. Lipid profile parameters in Malaysian dyslipidemic patients. The Kobe journal of the medical sciences

ABSTRACT Introduction The importance of serum lipids as cardiovascular risk factors is well recognized. However, most published studies have focused on western countries. The present study aimed to describe and analyze the lipid profile parameters in Malaysian dyslipidemic patients, and to identify concomitant clinical problems and risk factors associated with cardiovascular disease (CVD) among such patients. Methods: A retrospective record review was carried out at Hospital Universiti Sains Malaysia.The records were reviewed for 890 dyslipidemic patients who attended the hospital in 2007. Data were collected for age at time of presentation, sex, ethnicity, smoking status, pre-treatment lipid levels, and presence of associated illnesses. The study sample was classified according to the National Cholesterol Education Program Adult Treatment Panel III risk groups. Results: The mean (SD) values for total cholesterol, low-density lipoprotein cholesterol, high density lipoprotein cholesterol, and triglycerides were 6.4 (1.3), 4.1 (1.3), 1.4 (0.5) and 1.9 (1.2) mmol/l, respectively. Less than half of study sample (43.1%) had coronary heart disease and coronary heart diseases equivalents, 24.3% were at moderate risk, and 32.6% were at low risk. Hypertension was present in 79.9% of the study sample, while 27.5% were diabetics. Cardiovascular disease was reported among 17.9%. Logistic regression revealed that family history of premature cardiovascular disease, higher age risk group; ethnicity and total cholesterol were predictors for the development of cardiovascular disease. Conclusion: The present review showed that dyslipidemic patients had high total cholesterol levels, according to National Cholesterol Education Program Adult Treatment Panel III guidelines. They were clinically diagnosed at middle age. Hypertension and diabetes Phone: +6019-9875767 Fax: +609-7676922 E-mail: [email protected] E38 LIPID PROFILES IN MALAYSIAN DYSLIPIDEMIC PATIENTS were the commonest associated clinical problems. A large proportion of the patients were within the coronary heart disease or coronary heart disease risk equivalent group. Family history of premature cardiovascular disease, age, ethnicity, and total cholesterol are important risk factors for the development of cardiovascular disease in Malaysian dyslipidemic patients