Increased Number of Fibroblasts and Neovascularization after Tooth Extraction in Wistar Rats with Moderate-Intensity Continuous Exercise

Rapid wound healing after tooth extraction is expected to occur. Continuous moderate intensity exercise can improve the tissue oxygenation, that is required by fibroblasts and neovascularization to form granulation tissue which is an important process in wound healing. This study aimed to examine the increased number of fibroblasts and neovascularization after tooth extraction in wistar rat after continuous exercise with moderate intensity. Wistar rats were divided into 4 groups, control group and the other 3 is the treatment group. The treatment group was given moderate intensity continuous exercise for 6 weeks (swim test). In control group (K1), the number of fibroblast and neovascularization was observed five day after tooth extraction. In the treatment group (K2, K3, and K4), observation was conducted on day 3, 5, and 7 after tooth extraction. The number of fibroblasts and neovascularization of the control group was less than the treatment group. The data show a significant difference in control group (K1) with treatment group (K4) seven days after tooth extraction. There was increase in the number of fibroblasts and neovascularization in the group was given moderate intensity continuous exercise, and rapid wound healing process correlate with increased the number of fibroblasts and neovascularization