Design of the Model of Ratiometric Polymer Nanobiothermometer Based on Quantum Dots

To solve many modern biological and biotechnological tasks it is necessary to realize strictly control and regulation of temperature of the cells and their organelles. Thi stasks include control of various exo- and endothermic reactions, monitoring of tissues‘ and individual cell‘s temperature in in vitro researches and in vivo procedures such as the hyperthermia procedure that used for cancer treatment. The today known methods of measuring and controlling of temperature at the cellular level can not provide the necessary level of locality and accuracy due to too big size and heightened sensitivity to external factors. The real alternative of existing today methods is nanoscale temperature biosensor operating on a ratiometric principle and based on the composite structure from polymers and colloidal quantum dots. In this paper we present a working model and plan of investigation of ratiometric nanoscale polymer nanobiothermometer based on quantum dots. Keywords: thermosensors, quantum dots, local temperature, polymers, temperature measuremen

Correlative Microscopy: A Potent Tool for Biomedicine

The correlative microscopy method based on a combination of optical and electronic techniques that is increasingly widely used now, has a number of limitations. Here, an alternative approach is considered that uses scanning probe microscopy (SPM) technique to get high-resolution and ultra-high-resolution data. SPM greatly increases the possibilities of collecting new information (on topological, morphological, electrical, magnetic etc. properties). To obtain three-dimensional distributions of different parameters of the sample, ultramicrotomography is used, which allows to scan the sample in steps of up to 20 nm. The principal advantage of the approach is that spectral data are used which due to the combination in near field microscopy can be gained with high and ultrahigh resolution. All above mentioned features are implemented in a single instrument, which allows to have 3-D data and their distributions at the same instrumental platform. A special feature of the approach is the possibility to use all the power of micro(nano)spectral methods. Therefore, it would be more correct to name the proposed approach ”Correlative microspectroscopy”. Keywords: correlative microscopy, correlative microspectroscopy, scanning near-ielf optical microscopy, ultramicrotomography, Raman, TER

Technology for Creation and Detailed Analysis of Polymer Composites with Uniform Distribution of Quantum Dots and Liquid Crystals

One of the most actual tasks in biotechnology is the creation of a new generation of nanobiosensors with improved brightness, photo stability, and sensitivity. Compositions of polymers and colloidal quantum dots (QDs) are the most promising base to develop such sensors. This work presents the technology for creation and detailed analysis of nanostructured composite films based on polypropylene matrices with uniformly distributed CdSe/ZnS quantum dots and liquid crystals. Methods of optical microscopy, scanning probe microscopy and confocal fluorescen tmicrospectroscopy were used. The presence of liquid crystals in the composite allows additional control of QDs fluorescence. The methodology proposed is applicable not only to polypropylene, but also to other porous polymers. The results of this work indicate the possibility of creating high-quality polymer/QDs composite materials and open the way to the development of nanomaterials (nanosensors) with optical properties sensitive to various environmental parameters (electric field, photo irradiation, mechanical action, etc.). Keywords: quantum dot-polymer composites, nanoporous polypropylene, fluorescenc

Indication on the universal hadron substructure - constituent quarks

The universality of single-spin asymmetry on inclusive pi-meson production is discussed. This universality can be related to the hadron substructure - constituent quarks.Comment: 3 pages, 3 figures, references adde

Влияние регуляторов роста растений на возможность снижения инсектицидной нагрузки в агроценозах озимой пшеницы

Insecticides BI-58 new and Diazinone decrease the extent of damage of the winter wheat culm by cereals flies 7,2–8,0 times in comparison with the control. Combination of the studied insecticides with the mixtures of growth regulators allows to decrease the rate of insecticides application by 20 % without any increase of the culms damage by the pests.Показано, що інсектициди БІ-58 новий та Діазинон знижують ступінь пошкодження стеблин озимої пшениці злаковими мухами в 7,2–8 разів порівняно з контролем. При зниженні норм витрат досліджених інсектицидів у бакових сумішах із регуляторами росту рослин (біогуматом, триманом–1, емістимом С) на 20 % кількість пошкоджених стеблин приховано стебловими шкідниками (злаковими мухами) залишається на рівні використання повних доз.Показано, що інсектициди БІ-58 новий та Діазинон знижують ступінь пошкодження стеблин озимої пшениці злаковими мухами в 7,2–8 разів порівняно з контролем. При зниженні норм витрат досліджених інсектицидів у бакових сумішах із регуляторами росту рослин (біогуматом, триманом–1, емістимом С) на 20 % кількість пошкоджених стеблин приховано стебловими шкідниками (злаковими мухами) залишається на рівні використання повних доз

First study of radiation hardness of lead tungstate crystals at low temperatures

The electromagnetic calorimeter of PANDA at the FAIR facility will rely on an operation of lead tungstate (PWO) scintillation crystals at temperatures near -25 deg.C to provide sufficient resolution for photons in the energy range from 8 GeV down to 10 MeV. Radiation hardness of PWO crystals was studied at the IHEP (Protvino) irradiation facility in the temperature range from room temperature down to -25 deg.C. These studies have indicated a significantly different behaviour in the time evolution of the damaging processes well below room temperature. Different signal loss levels at the same dose rate, but at different temperatures were observed. The effect of a deep suppression of the crystal recovery process at temperatures below 0 deg.C has been seen.Comment: 10 pages 7 figure