An Efficient and Convenient Protocol for the Synthesis of Optically Active 1,2,4-Triazolo-[3,4-b]-[1,3,4]-Thiadiazole, 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives having L-Amino Acid Moieties

A series of novel bis triazolothiadiazole, 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives attached to L-amino acid moieties were synthesized in good yields using a simple and practical method. The structure of all synthesized compounds was confirmed by IR, 1H NMR, 13C NMR spectroscopy and elemental analysis.Keywords: Amino acid, triazolothiadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, phosphorus oxychloride, triazol