Postprandial blood glucose and insulin responses to pre-germinated brown rice in healthy subjects

Effects of pre-germinated brown rice (PGBR) on postprandial blood glucose and insulin concentrations were compared with brown rice (BR)and white rice (WR) in two studies. In the first study, we investigated the time course of postprandial blood glucose and insulin concentrations after ingesting 25% (W/V) glucose solution, PGBR, BR or WR in 19 healthy young subjects. In the second study, dose-dependent effect of PGBR on the time course of postprandial blood glucose concentrations was compared among 4 different mixtures of PGBR and WR in 13 healthy young subjects. They were solely PGBR, 2/3 PGBR(PGBR:WR= 2 : 1), 1/3 PGBR (PGBR : WR=1 : 2) and solely WR. Each sample was studied on a different day. The samples were selected randomly by the subjects. All the rice samples contained 50g of available carbohydrates. The previous day the subjects ate the assigned dinner by 9 : 00 pm and then were allowed only water until the examination. The next morning, they ingested each test rice sample with 150ml of water in 5-10min.Blood was collected into capillary tubes from finger at 0, 30, 60, 90 and 120 min after the ingestion. The incremental areas under the curve (IAUC) of blood glucose concentrations (IAUC-Glc) for 120min after the administration of PGBR and BR were lower than those after WR. In contrast the IAUC-Glc of BR and PGBR were not different (Study 1). The higher the ratio of PGBR/WR, the lower the glycemic index became (Study 2). These results suggest that intake of PGBR instead of WR is effective for the control of postprandial blood glucose concentration without increasing the insulin secretion

Detection of blood coagulation in an extracorporeal circuit using magnetic and absorbance properties

In extracorporeal circulation, intra-circuit blood coagulation can lead to serious problems. However, intra-circuit coagulation cannot be monitored in real-time and is only intermittently monitored by measuring the activated clotting time (ACT). As blood clotting progresses in a circuit, the color of the blood turns from bright red to dark red. And, changes in blood coagulation can be detected using devices with optical sensors because the absorbance is likely to change as blood coagulates. However, the absorbance may also increase when oxygen partial pressure is altered by artificial lungs. Thus, there is a need for a device that is not affected by blood oxygenation. Therefore, we used a magnet and a flux meter to assess changes in the magnetic force with blood coagulation. Thus, there is a need for a device that is not affected by blood oxygenation. Therefore, we used a magnet and a flux meter to assess changes in the magnetic force with blood coagulation. Measurements were made at different flux intensities to capture the magnetic flux changes during blood coagulation. Blood (100 ml) was stored in a beaker. Calcium chloride (CaCl2: 0.2 ml) was then added to the beaker to promote coagulation. Blood from the beaker was drawn into a syringe and set in the magnetic flux measurement fixture, and a magnet was fixed on top of the syringe for 24 min. The flux meter readings increased as the blood coagulated. The results suggest that it is possible to capture magnetic flux density changes during the process of blood coagulation. From the above may lead to the development of a device that monitors coagulation in extracorporeal circuits in real time by monitoring two aspects of the coagulation process: absorbance and magnetic flux density