1,818 research outputs found
Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation
AbstractB cells possess a variety of immune functions that are involved in normal and abnormal immune responses, including autoimmune disorders. Through murine models of intestinal inflammation, we here demonstrate a B cell subset that is induced in gut-associated lymphoid tissues and is characterized by CD1d upregulation. This B cell subset appears under a chronic inflammatory environment, produces IL-10, and suppresses progression of intestinal inflammation by downregulating inflammatory cascades associated with IL-1 upregulation and STAT3 activation rather than by altering polarized T helper responses. This study indicates that B cells, by producing cytokines such as IL-10, can act as regulatory cells in immunologically mediated inflammatory reactions
3-dimensional Gravity from the Turaev-Viro Invariant
We study the -deformed su(2) spin network as a 3-dimensional quantum
gravity model. We show that in the semiclassical continuum limit the
Turaev-Viro invariant obtained recently defines naturally regularized
path-integral la Ponzano-Regge, In which a contribution from
the cosmological term is effectively included. The regularization dependent
cosmological constant is found to be , where
. We also discuss the relation to the Euclidean Chern-Simons-Witten
gravity in 3-dimension.Comment: 11page
Angle-resolved photoemission spectroscopy of Co-based boride superconductor LaCo1.73Fe0.27B2
We have performed angle-resolved photoemission spectroscopy of Co-based
boride superconductor LaCo1.73Fe0.27B2 (Tc = 4.1 K), which is isostructural to
the 122-type Fe-pnictide superconductor with the pnictogen atom being replaced
with boron. We found that the Fermi level is located at a dip in the density of
states (DOS) in contrast to Co-pnictide ferromagnets. This reduction in DOS
together with the strong Co 3d-B 2p covalent bonding removes the ferromagnetic
order and may cause the superconductivity. The energy bands near the Fermi
level show higher three dimensionality and a weaker electron-correlation effect
than those of Fe pnictides. The Fermi surface topology is considerably
different from that of Fe pnictides, suggesting the difference in the
superconducting mechanism between boride and pnictide superconductors.Comment: 5 pages, 4 figure
SOLAR CYCLE DEPENDENCE OF THE DIURNAL ANISOTROPY OF 0.6 TeV COSMIC-RAY INTENSITY OBSERVED WITH THE MATSUSHIRO UNDERGROUND MUON DETECTOR
We analyze the temporal variation of the diurnal anisotropy of sub-TeV cosmic-ray intensity observed with the Matsushiro (Japan) underground muon detector over two full solar activity cycles in 1985-2008. We find an anisotropy component in the solar diurnal anisotropy superimposed on the Compton-Getting anisotropy due to Earth's orbital motion around the Sun. The phase of this additional anisotropy is almost constant at similar to 15:00 local solar time corresponding to the direction perpendicular to the average interplanetary magnetic field at Earth's orbit, while the amplitude varies between a maximum (0.043% +/- 0.002%) and minimum (similar to 0.008% +/- 0.002%) in a clear correlation with the solar activity. We find a significant time lag between the temporal variations of the amplitude and the sunspot number (SSN) and obtain the best correlation coefficient of +0.74 with the SSN delayed for 26 months. We suggest that this anisotropy might be interpreted in terms of the energy change due to the solar-wind-induced electric field expected for galactic cosmic rays (GCRs) crossing the wavy neutral sheet. The average amplitude of the sidereal diurnal variation over the entire period is 0.034% +/- 0.003%, which is roughly one-third of the amplitude reported from air shower and deep-underground muon experiments monitoring multi-TeVGCR intensity suggesting a significant attenuation of the anisotropy due to the solar modulation. We find, on the other hand, only a weak positive correlation between the sidereal diurnal anisotropy and the solar activity cycle in which the amplitude in the "active" solar activity epoch is about twice the amplitude in the "quiet" solar activity epoch. This implies that only one-fourth of the total attenuation varies in correlation with the solar activity cycle and/or the solar magnetic cycle. We finally examine the temporal variation of the "single-band valley depth" (SBVD) quoted by the Milagro experiment and, in contrast with recent Milagro's report, we find no steady increase in the Matsushiro observations in a seven-year period between 2000 and 2007. We suggest, therefore, that the steady increase of the SBVD reported by the Milagro experiment is not caused by the decreasing solar modulation in the declining phase of the 23rd solar activity cycle.ArticleThe Astrophysical Journal. 712(2):1100-1106 (2010)journal articl
Comments on D-branes in Kazama-Suzuki models and Landau-Ginzburg theories
We study D-branes in Kazama-Suzuki models by means of the boundary state
description. We can identify the boundary states of Kazama-Suzuki models with
the solitons in N=2 Landau-Ginzburg theories. We also propose a geometrical
interpretation of the boundary states in Kazama-Suzuki models.Comment: 28 pages, 2 figure
Non-critical Heterotic Superstrings in Various Dimensions
We construct heterotic string theories on spacetimes of the form R^{d-1,1}
times N=2 linear dilaton, where d=6,4,2,0. There are two lines of
supersymmetric theories descending from the two supersymmetric ten-dimensional
heterotic theories. These have gauge groups which are lower rank subgroups of
E_{8} times E_{8} and SO(32). On turning on a (2,2) deformation which makes the
two dimensional part a smooth SL_{2}(R)/U(1) supercoset, the gauge groups get
broken further. In the deformed theories, there are non-trivial moduli which
are charged under the surviving gauge group in the case of d=6. We construct
the marginal operators on the worldsheet corresponding to these moduli.Comment: 27 pages, harvmac. v2 reference adde
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