19 research outputs found

    Fibrinogen–platelet ratio and pancreatic cancer

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    Background : Several prognostic factors were reported in pancreatic cancer. The fibrinogen–platelet ratio (FPR) was reported as a prognostic factor of resectable gastric cancer. In this report, the FPR was evaluated in patients with resectable pancreatic cancer. Methods : Between 2004 and 2019, 163 patients with curative resection for pancreatic cancer were enrolled. Cases of non-curative resection were excluded. The FPR was calculated using the preoperative plasma fibrinogen and the platelet counts and the cut-off value was determined by receiver operating characteristic (ROC) curve analysis. The patients were divided into high and low FPR groups according to this cut-off value. Results : The cut-off value of FPR was 25.2. Among age, sex, body mass index (BMI), and surgical factors including surgery type, volume of blood loss and surgery time, there was no significant difference between the two groups. Patients in the low FPR group had significantly better overall survival (OS) and relapse-free survival (RFS) compared with the high FPR group (P 300 U / ml, and receipt of adjuvant chemotherapy were independent risk factors for OS and DFS. Conclusions : The FPR might be a prognostic factor for patients with resectable pancreatic cancer

    Basic Performance Evaluation of the First Model of 4-Dimensional CT-Scanner

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    This work was carried out to evaluate the basic performances for 4 dimensional computed tomography (4D-CT) scanner, which employs continuously rotating cone-beam. The performances were evaluated with the same method as the conventional CT, because the standard method of evaluating 4D-CT has not yet been established, and we think this result was helpful to establish it. 4D-CT scanner can give dynamic volume imaging data continuously and with high-speed. Volume range of the longitudinal length is about 10cm. It uses a wide-area 2D detector designed on the basis of the present CT technology. The number of elements are 912(channels) x 256(segments), element size is approximately 1mm x 1mm, scanning time is 1sec, and data sampling rate is 900 views (frames)/sec. Feldkamp algorithm was used for reconstruction. We measured six items as follows with stationary phantoms for 4D-CT, and compared them with the results of conventional multi-detector CT. 1.Noise, 2.Distortion, 3.Low contrast and high contrast resolution, 4.Spatial resolution, 5.Artifact, 6.Exposure dose measurement. The results were isotropic except for the evaluation of distortion in which small distortions gradually appeared as coming off the center of phantom in longitudinal direction. We confirmed a uniformity of CT value in longitudinal and transaxial sections. The evaluations of other items were very close to those of conventional CT.SPI
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