Grenzüberschreitungen : Kulturelle Transfers als aktuelle Forschungsperspektive

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Crossing Central Europe

This volume studies elements of Austro-Hungarian or Central European culture that were common across linguistic, national, and ethnic communities, and shows how some of these commonalities survived or were transformed by the turmoil of the 20th century: two world wars, a major depression between the wars, Stalinism and the Iron Curtain

Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy

Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy.BackgroundUnilateral loss of kidney function is followed by compensatory contralateral growth. The early, genome-wide transcriptional response of the untouched kidney to unilateral ureteral obstruction (UUO) or unilateral nephrectomy is unknown.MethodsTwelve adult male Sprague-Dawley rats were subjected to UUO and twelve rats to unilateral nephrectomy. At time points 12, 24, and 72 hours after insult four rats each were sacrificed and the contralateral kidney harvested for genome-wide gene expression analysis, transcription factor analysis, and histomorphology.ResultsMicroarray studies revealed that the majority of differentially expressed transcripts were suppressed in UUO and unilateral nephrectomy compared to control kidneys. The function of these suppressed genes is predominantly growth inhibition and apoptosis suggesting a net pro-hypertrophic response. Insulin-like growth factor-2 (IGF-2)-binding protein was one of the few activated genes. We observed a distinctly different molecular signature between UUO and unilateral nephrectomy at the three time points investigated. The early response in UUO rats suggests a counterbalance to the nonfiltering kidney by activation of transport pathways such as the aquaporins. Unilateral nephrectomy kidneys, on the other hand, respond immediately to contralateral nephrectomy by activation of cell cycle regulators such as the cyclin family. Several genes with weakly defined function were found to be associated with either UUO or unilateral nephrectomy. Transcription factor analysis of the identified transcripts suggests common regulation at least of some of these genes. All kidneys showed normal histology.ConclusionRelease of growth inhibition by nephrectomy leads to immediate cell cycle activation after unilateral nephrectomy, whereas UUO kidneys counterbalance filtration failure by activation of several transporters

Mnemosyne migriert: Transformationen des Gedächtnisses in der österreichischen Gegenwartsliteratur

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Michael Werner, Bénédicte Zimmermann (éds.), De la comparaison à l’histoire croisée, Paris: Seuil 2004

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The Letters of Franz Blei

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Carmen Sippl, Slavica der Hermann-Bahr-Sammlung an der Universitätsbibliothek Salzburg, Berne :P. Lang 2002

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Grenzüberschreitungen: Migration in der deutschen und österreichischen Literatur der Ge-genwart

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Transformationen der Inspiration :Auf Spurensuche mit Christoph Ransmayrs Roman „Die letzte Welt“

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“Could one really change one’s language as if it were a shirt”: The Austro-Canadian writer Henry Kreisel

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