153 research outputs found
Optical properties of poly[(disilanylene)oligophenylenes]
Optical Science, Engineering and Instrumentation '97, 1997, San Diego, CA, United StatesKatsumi Yoshino, Masaharu Hirohata, Kazuya Tada, Akihiko Fujii, Masanori Ozaki, Akinobu Naka, and Mitsuo Ishikawa "Optical properties of poly(disilanylene oligophenylenes)", Proc. SPIE 3145, Optical Probes of Conjugated Polymers, (1 December 1997). DOI: https://doi.org/10.1117/12.28414
Fatigue Property and Cytocompatibility of a Biomedical Co–Cr–Mo Alloy Subjected to a High Pressure Torsion and a Subsequent Short Time Annealing
In the present study, we evaluated the effects of high pressure torsion (HPT) and subsequent short time annealing processing on fatigue properties and cytocompatibility of the biomedical Co–Cr–Mo alloy (CCM). Before processing, CCM was solution treated (CCMST) to achieve a microstructure composed of coarse single γ-phase equiaxed grains with no internal strain. Through HPT processing, an inhomogeneous microstructure containing both micro- and nano-scaled grains is obtained in CCM specimens, which were named as CCMHPT, accompanied by high internal strain and extensive ε martensite. Following a subsequent short time annealing, a uniform single γ-phase ultrafine-grained microstructure with small local strain fields dispersed forms in CCM specimens, which were named as CCMHPTA. This microstructure change improves fatigue strength in CCMHPT, and further in CCMHPTA, because of the enhanced crack initiation and/or propagation resistance. For cytocompatibility evaluation, the cells cultured on CCMST show an immobilization tendency, while those cultured on CCMHPT exhibit a locomotion tendency. The cells cultured on CCMHPTA have an intermediate pattern. Compared with CCMST, much larger numbers of cells are proliferated in both CCMHPT and CCMHPTA. All these results demonstrate that the CCMHPTA offers an improved fatigue property and a good cytocompatibility. Therefore, it is promising for use in biomedical applications
Living-donor liver transplantation : present status and future perspective
About 15 years have passed since the first liver transplant from a living donor (living donor liver transplantation : LDLT), and the status of the procedure has since been established as a standard cure for end-stage liver disease in Japan where liver transplantation (LTx) from deceased donors has not yet been accepted. However, the following problems are surfacing with the increase in the number of LDLTs between adults : graft size mismatching, an ABO blood-type incompatible transplantation, the expansion of LDLT indication to hepatocellular carcinoma (HCC), the relapse of hepatitis C after LDLT, marginal donors, and the freedom from immunosuppressive treatment. In this article we outline the present conditions of these problems and the future view of the LDLT
アンゼンナ フククウキョウカ タンノウ テキシュツジュツ ノ タメ ノ ジュツゼン ガゾウ シンダン ノ ヤクワリ
Laparoscopic cholecystectomy becomes one of the standard procedures for digestive surgeons. There is consensus that careful dissection and correct elucidation of the anatomy avoids the complications during cholecystectomy. From May 1991 to March 2005, 433 cases of laparoscopic cholecystectomy were retrospectively analyzed. Conversion to open cholecystectomy was required in 19 cases(4.4%)and the rate of vascular injury or bile duct injury was 0.7% each. CT angiography was effective for preoperative evaluation of vascular anatomy. In many cases, middle hepatic vein was located near gallbladder bed. CT cholangiography was also useful for obtaining information of the biliary tract. Careful evaluation of preoperative CT angiography and cholangiography contributes to decrease the risk of complications during laparoscopic cholecystectomy
Multiple hepatic angiomyolipomas with a solitary omental angiomyolipoma
Angiomyolipoma (AML) is a rare benign tumor that occurs most commonly in the kidney. Lesions in the liver are usually solitary and multiple AMLs of the liver are extremely rare. Furthermore, extra renal or hepatic AML are rarely found. We report an unusual case of a 34-year-oldman with a solitary omental AML and multiple hepatic AMLs. At the age of 23, the patient underwent right nephrectomy and enucleation of a left renal tumor because of bilateral AMLs. At the age of 34, more than 6 lesions in the liver and an enlarged solitary omental AML were discovered. The omental tumor, 50×40mm, 49g,was extirpated it was well-defined and encapsulated a soft elastic mass. Histologically it was an epithelioid AML and positive for the melanogenesis-related marker HMB- 45, the same as the earlier right renal tumor. We describe the first case of a solitary omental AML, which had metastasized, and with more than 6 hepatic AMLs
セイタイ カンイショク ニオケル カショウ グラフト ノ ビョウタイ セイリ ト チリョウ センリャク
Introduction : To save the small-for-size graft in living donor adult liver transplantation (LDALT), it is necessary to overcome the following problems:1)excessive portal inflow;2)
graft congestion;3)small functional liver mass ; and4)inadequate intragraft responses.
Treatments for the small-for-size graft.
1)To avoid excessive portal inflow(: a)Splenctomy or splenic artery ligation to reduce portal pressure and flow ; and b)Portocaval shunt to reduce portal pressure and flow.
2)To avoid graft congestion : a)Graft venoplasty and graft hepatic vein to the IVC anastomosis in left lobe grafts, and reconstruction of significant venous tributaries from the middle hepatic vein in right lobe grafts ; and(b)Intraportal administration of drugs(PG-E1, etc.)to prevent microcirculatory disturbance.
3)To avoid liver failure due to small functional liver mass : Hyperbaric oxygen therapy is a feasible option for a persistent functional hyperbiliruminemia.
4)To modulate inadequate intragraft responses(: a)Induction of heat shock protein into the graft to suppress up-regulation of inflammatory cytokines, and to improved survival rate after 95%-hepatectomy(Hx)in rats ; and(b)Slow-down of liver regeneration to reduce liver injury and to improve survival rate after90%-Hx in rats.
Conclusions : Pathophysiology-oriented strategy against small-for-size graft is effective in LDALT
Rapid-growing solitary necrotic nodule of the liver
The solitary necrotic nodule of the liver is an uncommon nonmalignant lesion with an uncertain etiology. The lesion was defined as a nodule with a completely necrotic core and fibrous capsule etc. and without a consistency of viable cells. The characteristic features of this benign lesion on the imaging modalities are similar to the metastatic tumor. In this paper we discuss the case of a rapid-growing solitary necrotic nodule of the liver occurring in a patient with chronic renal failure on hemodialysis. The lesion located on the left median lobe of the liver had rapidly enlarged in diameter in the last seven months. Despite some examinations by imaging modalities to confirm the preoperative diagnosis, we were unable to visually confirm. Several histological examinations using a needle biopsy specimen were performed, but the diagnosis was all necrotic tissue. However, we recommended an extended left hepatic lobectomy for this rapid-growing lesion since cholangiocarcinoma with necrosis could be hardly differentiated. Permanent histology revealed that the lesion was solitary necrotic nodule. We consider that permanent histology of the entire lesion is possibly the only accurate method of diagnosis. Since the solitary necrotic nodule does not indicate malignancy, hepatic resection should be performed
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