6,453 research outputs found
Using the Man9(GlcNAc)2 â DC-SIGN pairing to probe specificity in photochemical immobilization
We demonstrate the expected preference of an immobilised oligosaccharide Man(9)(GlcNAc)(2) upon a 96-well photochemical array, for its known receptor, the cell-surface lectin Dendritic Cell-Specific ICAM3 Grabbing Nonintegrin (DC-SIGN) when compared to immobilised competing monosaccharides
Early CRT monitoring using time-domain optical coherence tomography does not add to visual acuity for predicting visual loss in patients with central retinal vein occlusion treated with intravitreal ranibizumab:A secondary analysis of trial data
Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central retinal vein occlusion. The authors also assessed detectability of response to treatment
Implications of very rapid TeV variability in blazars
We discuss the implications of rapid (few-minute) variability in the TeV flux
of blazars, which has been observed recently with the HESS and MAGIC
telescopes. The variability timescales seen in PKS 2155-304 and Mrk 501 are
much shorter than inferred light-crossing times at the black hole horizon,
suggesting that the variability involves enhanced emission in a small region
within an outflowing jet. The enhancement could be triggered by dissipation in
part of the black hole's magnetosphere at the base of the outflow, or else by
instabilities in the jet itself. By considering the energetics of the observed
flares, along with the requirement that TeV photons escape without producing
pairs, we deduce that the bulk Lorentz factors in the jets must be >50. The
distance of the emission region from the central black hole is less
well-constrained. We discuss possible consequences for multi-wavelength
observations.Comment: 5 pages, no figures, accepted for publication in Monthly Notices of
the Royal Astronomical Society Letter
Electrocortical components of anticipation and consumption in a monetary incentive delay task
In order to improve our understanding of the components that reflect functionally important processes during reward anticipation and consumption, we used principle components analyses (PCA) to separate and quantify averaged ERP data obtained from each stage of a modified monetary incentive delay (MID) task. Although a small number of recent ERP studies have reported that reward and loss cues potentiate ERPs during anticipation, action preparation, and consummatory stages of reward processing, these findings are inconsistent due to temporal and spatial overlap between the relevant electrophysiological components. Our results show three components following cue presentation are sensitive to incentive cues (N1, P3a, P3b). In contrast to previous research, rewardârelated enhancement occurred only in the P3b, with earlier components more sensitive to breakâeven and loss cues. During feedback anticipation, we observed a lateralized centroparietal negativity that was sensitive to response hand but not cue type. We also show that use of PCA on ERPs reflecting reward consumption successfully separates the reward positivity from the independently modulated feedbackâP3. Last, we observe for the first time a new reward consumption component: a late negativity distributed over the left frontal pole. This component appears to be sensitive to response hand, especially in the context of monetary gain. These results illustrate that the time course and sensitivities of electrophysiological activity that follows incentive cues do not follow a simple heuristic in which reward incentive cues produce enhanced activity at all stages and substages
NODULAR MASSES IN THE SWIMBLADDER AND VISCERAL FAT OF THE WALLEYE, \u3ci\u3eSTIZOSTEDION VITREUM\u3c/i\u3e
In April of 1990, a 1.8 kg walleye was found to contain hard cysts or nodules in the swimbladder and visceral fat. The nodules appeared to be formed around a worm-like mass. The nodules (10 ± 5 mm in diameter) were composed of five to seven layers of tightly packed granules, that were at least partially calcified and the layers were held together by a sticky matrix. The outer coat of the nodule was convoluted with many protuberances. This is a first report of such cysts from fish and they appear to be similar to nodules induced by worms (encysted nematodes) in the intestines of swine and ruminants
NODULAR MASSES IN THE SWIMBLADDER AND VISCERAL FAT OF THE WALLEYE, \u3ci\u3eSTIZOSTEDION VITREUM\u3c/i\u3e
In April of 1990, a 1.8 kg walleye was found to contain hard cysts or nodules in the swimbladder and visceral fat. The nodules appeared to be formed around a worm-like mass. The nodules (10 ± 5 mm in diameter) were composed of five to seven layers of tightly packed granules, that were at least partially calcified and the layers were held together by a sticky matrix. The outer coat of the nodule was convoluted with many protuberances. This is a first report of such cysts from fish and they appear to be similar to nodules induced by worms (encysted nematodes) in the intestines of swine and ruminants
Radiatively-Driven Outflows and Avoidance of Common-Envelope Evolution in Close Binaries
Recent work on Cygnus X-2 suggests that neutron-star or black-hole binaries
survive highly super-Eddington mass transfer rates without undergoing
common-envelope evolution. We suggest here that the accretion flows in such
cases are radiation pressure-dominated versions of the "ADIOS" picture proposed
by Blandford and Begelman (1999), in which almost all the mass is expelled from
large radii in the accretion disk. We estimate the maximum radius from which
mass loss is likely to occur, and show that common-envelope evolution is
probably avoided in any binary in which a main-sequence donor transfers mass on
a thermal timescale to a neutron star or black hole, even though the mass
transfer rate may reach values of 0.001 solar masses per year. This conclusion
probably applies also to donors expanding across the Hertzsprung gap, provided
that their envelopes are radiative. SS433 may be an example of a system in this
state.Comment: 4 pages, submitted to Astrophysical Journal Letters, 26 March 199
A space division multiplexed free-space-optical communication system that can auto-locate and fully self align with a remote transceiver
Free-Space Optical (FSO) systems offer the ability to distribute high speed digital links into remote and rural communities where terrain, installation cost or infrastructure security pose critical hurdles to deployment. A challenge in any point-to-point FSO system is initiating and maintaining optical alignment from the sender to the receiver. In this paper we propose and demonstrate a low-complexity self-aligning FSO prototype that can completely self-align with no requirement for initial manual positioning and could therefore form the opto-mechanical basis for a mesh network of optical transceivers. The prototype utilises off-the-shelf consumer electrical components and a bespoke alignment algorithm. We demonstrate an eight fibre spatially multiplexed link with a loss of 15âdB over 210âm
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