Uprawnienia Prezesa UOKiK na platformach sprzedażowych w związku ze zgłoszeniami „naruszeń” praw własności intelektualnej, które mogą skutkować ograniczeniem konkurencji

W EUIPO istnieje możliwość zarejestrowania w ciągu kilku dni wzoru wspólnotowego, który jest chroniony na terytorium całej UE. Procedura rejestracji nie wymaga sprawdzenia czy wzór spełnia ustawowe przesłanki (tzw. system rejestracji). Ostatnio jest ona wykorzystywana do monopolizacji sprzedaży produktów, które od lat są w obrocie. Sprawa dotyczy wyłącznie platform sprzedażowych, gdyż one stosują regulaminy naruszeń PWI, traktujące w automatyczny sposób udzielone prawa własności przemysłowej i kwalifikują pozostałych sprzedawców jako naruszycieli. Ze względu na to, że sprzedaż online w znacznej mierze realizowana jest poprzez platformy sprzedażowe, problem nabiera znaczenia. Artykuł ma na celu analizę, na podstawie akt prawnych dotyczących sprzedaży online (jak rozporządzenie Platform-to-Business czy procedowany jeszcze Digital Services Act), zakresu uprawnień Prezesa UOKiK do wpływania na treść regulaminów naruszeń PWI na poszczególnych platformach sprzedażowych. Takie działanie mieści się bowiem w ramach ochrony konsumentów oraz ochrony interesów przedsiębiorców podejmowanej w interesie publicznym

Validation of the Polish-language version of the COPD Assessment Test

INTRODUCTION The COPD Assessment Test (CAT) is a standardized patient–completed tool dedicated to assessment of symptom severity. While the Polish CAT version has been used for a few years, it has not been validated so far. OBJECTIVES The aim of the study was to validate the Polish‑language version of the CAT questionnaire by assessing its reproducibility and reliability. PATIENTS AND METHODS Validation of the Polish‑language version of the CAT questionnaire was a substudy of the international multicenter observational cross‑sectional POPE survey of patients with chronic obstructive pulmonary disease (COPD) in Central and Eastern European countries. The study was completed in 395 outpatients with stable disease at least 4 weeks before the survey. Validation was performed with the use of the Spearman correlation and Cronbach α coefficients, Cohen κ test, and the Bland–Altman procedure. RESULTS The internal consistency assessed by the Cronbach α coefficient was 0.87 for the questionnaire and 0.84 to 0.86 for its separate items. The repeatability of the questionnaire was good to very good (Cohen κ, 0.76–0.85; P <0.01). The Spearman coefficient for the sum of scores of test–retest responses was 0.95 (P <0.01). The Bland–Altman analysis revealed very good test–retest and interrater reliability, with the mean difference between test I and test II results of –0.556 (95% CI, –0.345 to 0.767). CONCLUSIONS The Polish version of the CAT questionnaire is a reproducible and reliable instrument for evaluation of patients with COPD and should be recommended for use in clinical practice

The influence of the oral condition on the menthal and phisical well-beeing of elderly people

Stan jamy ustnej ma istotny wpływ na dobrostan psychiczny i fizyczny każdego człowieka. W pracy przedstawiono dolegliwości, z jakimi pacjenci w starszym wieku zgłaszają się do Katedry i Zakładu Periodontologii Akademii Medycznej w Lublinie. Badano związek zaburzeń występujących w jamie ustnej z obecnością współistniejących chorób ogólnoustrojowych. W pracy wskazuje się na konieczność kompleksowej - lekarskiej i stomatologicznej - opieki nad osobami starszymi.The condition of the oral cavity significantly influences mental and physical well-being of the individual. This study presents a range of complaints in elderly patients treated in the Department and Chair of Periodontology of Medical University in Lublin. Interrelation between oral and systemic disease was studied. The relevance of complex medical and dental care in the elderly is underlined

Preventive periodontal treatment can be realized in the oral cavities of elderly people

Wraz z wiekiem zwiększa się ryzyko powstawania nieodwracalnych zmian w przyzębiu z powodu zwiększonej obecności kamienia nazębnego w miejscach retencyjnych, takich jak wypełnienia czy uzupełnienia protetyczne. Ponadto u osób starszych po 70. roku życia w związku ze stałą progresją zaniku kości wyrostka zębodołowego mniej pomyślne są prognozy lecznicze. W pracy przedstawiono zalety profilaktycznych domowych i profesjonalnych zabiegów usuwania kamienia nazębnego, które zmniejszają ryzyko powstawania powikłań ogólnoustrojowych.Age is a risk factor for periodontit is and greater periodontal destruction because of the increased presence ofplaque-retentive restorations and crowns. Prognosis given to 70-year-old patients are less favorable because of the progressive periodontal destruction over time. The paper describes various qualities of home and professional prophylaxis used in the removal of bacterial plaque from teeth, which prevents the risk of systemic diseases

Kandydoza jamy ustnej

The increase in prevalence of local and systemic candidiasis is related with global population aging, implementing invasive diagnostic and therapeutic methods, aggressive cancer treatment, organ and bone marrow transplants, and corticosteroid and immunosuppressive therapy. Clinical observations indicate that the patient&#8217;s general condition, age, diet and social setting affect the susceptibility to oral candidiasis.Starzenie się społeczeństw oraz powszechne wprowadzenie do lecznictwa inwazyjnych metod diagnostycznych i terapeutycznych, agresywnych metod leczenia nowotworów, transplantacji narządów i szpiku kostnego, leków immunosupresyjnych i kortykosteroidów spowodowało większy niż kiedykolwiek rozwój grzybic powierzchniowych i układowych. Z obserwacji klinicznych wynika, że o rozwoju grzybicy (kandydozy) jamy ustnej decyduje odporność organizmu, wiek, sposób odżywiania oraz warunki socjalne

Safety and Efficacy of Isolated Endoscopic Cyclophotocoagulation in Pseudophakic Patients with Primary Open-Angle Glaucoma—12-Month Follow-Up

Background: We evaluated the safety and efficacy of endoscopic cyclophotocoagulation (ECP) for eyes with primary open-angle glaucoma (POAG). Methods: We included a total of 104 pseudophakic eyes treated with ECP. Visual acuity and intraocular pressure (IOP, mmHg) measurements were evaluated preoperatively and on days 1 and 7 and 2 and 12 months postoperatively. IOP ≤ 15 or ≥30% reduction from baseline were defined as therapeutic success. Results: The mean baseline IOP was 23.89 ± 8.63, and it decreased significantly at the day 1 (16.25 ± 7.32, p &lt; 0.0001), day 7 (17.81 ± 6.37, p &lt; 0.0001), 2nd month (17.77 ± 8.54, p &lt; 0.0001) and 12th month (16.42 ± 7.05, p &lt; 0.0001) follow-up visits. Therapeutic success was achieved in 55 (61.80%) eyes at the 12-month follow-up. Patients with POAG duration longer than 10 years or those using alpha agonist eye drops had a lower rate of therapeutic success (odds ratio: 0.52, 95% CI = 0.32–0.85, p &lt; 0.05 and odds ratio: 0.92, 95% CI = 0.55–0.95, p = 0.024, respectively). A longer disease course was associated with higher IOP values (Rs =+0.281; p = 0.024) postoperatively. The number of antiglaucoma medications decreased significantly from 2.55 ± 1.16 to 2.11 ± 1.14 (p = 0.003). The ECP complications included a minor IOP increase (9.37%), pupil irregularity (15.73%), and the presence of fibrin (3.29%). Conclusions: The ECP is an effective and safe option, especially in eyes with a shorter glaucoma course

Validation of FES-I and Short FES-I Scales in the Polish Setting as the research tools of choice to identify the fear of falling in older adults

Fear of falling is associated with a clear hazard to individual self-reliance, reduced physical activity, as well as a sense of shame and loss of self-confidence. The present study aimed to complete the applicable translation and validation protocol for the Falls Efficacy Scale—International (FES-I) tool, following its prior adaptation to ensure full compatibility with the Polish setting. The FES-I questionnaire, along with its abridged version, was translated in line with the recommended standards of the MAPI Institute, taking into account both the cultural fabric and pertinent language specifics of the country. The survey was attended by 740 individuals (N = 740; 463 women, 277 men), over 60 years old. All respondents were required to complete both the FES-I and FES-I (Short) questionnaires twice, following an intervening period, and subsequently had their responses statistically assessed. The FES-I questionnaire, along with its abridged version, may be recommended as an effective assessment tool for addressing the fear of falling issue among the older adults, consequently allowing the teams of attending physicians, physiotherapists, psychologists, or psychiatrists to complete an unambiguous diagnosis, with a view to helping the patients overcome this particular type of anxiety

Endovascular versus medical therapy in posterior cerebral artery stroke: role of baseline NIHSS and occlusion site.

Background: Acute ischemic stroke (AIS) with isolated posterior cerebral artery occlusion (iPCAO) lacks management evidence from randomized trials. We aimed to evaluate whether the association between endovascular treatment (EVT) and outcomes in iPCAO-AIS is modified by initial stroke severity (baseline NIHSS) and arterial occlusion site. Methods: Based on the multicenter, retrospective, case-control study of consecutive iPCAO-AIS patients (PLATO study), we assessed the heterogeneity of EVT outcomes compared to medical management (MM) for iPCAO, according to baseline NIHSS (≤6 vs. >6) and occlusion site (P1 vs. P2), using multivariable regression modelling with interaction terms. The primary outcome was the favorable shift of 3-month mRS. Secondary outcomes included excellent outcome (mRS 0-1), functional independence (mRS 0-2), symptomatic intracranial hemorrhage (sICH) and mortality. Results: From 1344 patients assessed for eligibility, 1,059 were included (median age 74 years, 43.7% women, 41.3% had intravenous thrombolysis), 364 receiving EVT and 695 MM. Baseline stroke severity did not modify the association of EVT with 3-month mRS distribution (pint=0.312), but did with functional independence (pint=0.010), with a similar trend on excellent outcome (pint=0.069). EVT was associated with more favorable outcomes than MM in patients with baseline NIHSS>6 (mRS 0-1: 30.6% vs. 17.7%, aOR=2.01, 95%CI=1.22-3.31; mRS 0-2: 46.1% vs. 31.9%, aOR=1.64, 95%CI=1.08-2.51), but not in those with NIHSS≤6 (mRS 0-1: 43.8% vs. 46.3%, aOR=0.90, 95%CI=0.49-1.64; mRS 0-2: 65.3% vs. 74.3%, aOR=0.55, 95%CI=0.30-1.0). EVT was associated with more sICH regardless of baseline NIHSS (pint=0.467), while the mortality increase was more pronounced in patients with NIHSS≤6 (pint=0.044, NIHSS≤6: aOR=7.95,95%CI=3.11-20.28, NIHSS>6: aOR=1.98,95%CI=1.08-3.65). Arterial occlusion site did not modify the association of EVT with outcomes compared to MM. Conclusion: Baseline clinical stroke severity, rather than the occlusion site, may be an important modifier of the association between EVT and outcomes in iPCAO. Only severely affected patients with iPCAO (NIHSS>6) had more favorable disability outcomes with EVT than MM, despite increased mortality and sICH

Aspiration Versus Stent Retriever Thrombectomy for Distal, Medium Vessel Occlusion Stroke in the Posterior Circulation: A Subanalysis of the TOPMOST Study.

BACKGROUND The optimal endovascular strategy for reperfusing distal medium-vessel occlusions (DMVO) remains unknown. This study evaluates angiographic and clinical outcomes of thrombectomy strategies in DMVO stroke of the posterior circulation. METHODS TOPMOST (Treatment for Primary Medium Vessel Occlusion Stroke) is an international, retrospective, multicenter, observational registry of patients treated for DMVO between January 2014 and June 2020. This study analyzed endovascularly treated isolated primary DMVO of the posterior cerebral artery in the P2 and P3 segment. Technical feasibility was evaluated with the first-pass effect defined as a modified Thrombolysis in Cerebral Infarction Scale score of 3. Rates of early neurological improvement and functional modified Rankin Scale scores at 90 days were compared. Safety was assessed by the occurrence of symptomatic intracranial hemorrhage and intervention-related serious adverse events. RESULTS A total of 141 patients met the inclusion criteria and were treated endovascularly for primary isolated DMVO in the P2 (84.4%, 119) or P3 segment (15.6%, 22) of the posterior cerebral artery. The median age was 75 (IQR, 62-81), and 45.4% (64) were female. The initial reperfusion strategy was aspiration only in 29% (41) and stent retriever in 71% (100), both achieving similar first-pass effect rates of 53.7% (22) and 44% (44; P=0.297), respectively. There were no significant differences in early neurological improvement (aspiration: 64.7% versus stent retriever: 52.2%; P=0.933) and modified Rankin Scale rates (modified Rankin Scale score 0-1, aspiration: 60.5% versus stent retriever 68.6%; P=0.4). In multivariable logistic regression analysis, the time from groin puncture to recanalization was associated with the first-pass effect (adjusted odds ratio, 0.97 [95% CI, 0.95-0.99]; P<0.001) that in turn was associated with early neurological improvement (aOR, 3.27 [95% CI, 1.16-9.21]; P<0.025). Symptomatic intracranial hemorrhage occurred in 2.8% (4) of all cases. CONCLUSIONS Both first-pass aspiration and stent retriever thrombectomy for primary isolated posterior circulation DMVO seem to be safe and technically feasible leading to similar favorable rates of angiographic and clinical outcome