A Bibliometric Analysis of the Evolution of State-of-the-Art Blockchain Technology (BCT) in the Agrifood Sector from 2014 to 2022

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Knowledge, attitude and practice of pharmacovigilance towards adverse drug reactions reporting among health care professionals (nurses) in a tertiary care teaching hospital in Eastern India: an observational study

Background: Nursing staffs spend most time in patient care and are bedside caregivers. To expect voluntary reporting of adverse reactions, it is essential that they possess proper knowledge, right attitude and practice reporting. Therefore, the present study was aimed to assess the Knowledge, Attitude and Practice of Pharmacovigilance towards ADRs reporting.Methods: A prospective, cross sectional, observational, questionnaire-based survey was conducted among nurses in a tertiary care teaching hospital in Eastern India. Questionnaire containing 15 questions was used to assess knowledge, attitude and practice. The questionnaire was administered to 150 nurses. Analysis of data was done using statistical software..Results: The response rate in our study was 86.67%. Nurses have good knowledge of pharmacovigilance and adverse reaction. However, only 10% have reported an adverse reaction in our study. This shows that in spite of having a good knowledge of reporting, nurses have poor attitude, which is reflected by a low reporting rate. Nurses opined that taking patient care is of prime importance than report an adverse reaction. This corroborates the low reporting rate in our set up.Conclusions: Majority of nurses have good knowledge on pharmacovigilance and adverse drug reaction. The concern remains on the low reporting rate. Continuous training programmes, and reminders likely to enhance the voluntary reporting from the nursing staffs

Adverse drug reaction reporting in a tertiary care teaching hospital in eastern India: a retrospective study

Background: Adverse drug reactions (ADRs) are one of the prime causes of morbidity and mortality, increase in hospital stay and socioeconomic burden on the patients. Periodic monitoring aids in formulating methods for safe usage of medicines in hospitals. This study was undertaken to study the patterns, assessment of causality, severity, preventability, body systems affected from ADRs received by the Pharmacovigilance cell, Department of Pharmacology between April 2018 to June 2019.Methods: The present study is an observational, retrospective, non-interventional analysis of voluntarily reported ADRs. Demography of patients, causative drugs, reactions, outcome, and severity are recorded. Data were analysed and expressed in numbers, percentages.Results: A total of 180 ADRs were spontaneously reported. Dermatology (42.8%), psychiatry (23.9%) and general medicine (18.3%) are the major departments reporting ADRs in our hospital. 60.6% reports were in males. The body system with maximum reactions is dermatological (51.1%). Drug class most commonly affected is anti-microbials (36.1%). Paracetamol (8.9%) is the most common drug with reactions. Causality assessment stated that 41.7% ADRs are probable and 58.3% were possible. Severity assessment showed 86.7% as mild and 13.3% as moderate. Preventability assessment stated that 93.3% ADRs not preventable, 5.6% probably preventable and 1.1% definitely preventable.Conclusions: The study provides a valuable insight with regards to the pattern of ADRs in our hospital. This will be useful in initiating a reporting culture, increase awareness, reducing under-reporting of ADR in our set up

Adverse cutaneous drug reactions reporting in a tertiary care teaching hospital in Eastern India: a retrospective study

Background: Any unwanted changes to mucous membrane, skin, its appendages and drug eruptions related adverse events are known as adverse cutaneous drug reaction (ACDR). It has 2-5% incidence in developing countries. The current study was undertaken to analyse adverse cutaneous drug reactions spectrum clinically, drugs responsible, assessment of causality, severity, and preventability in our setup.Methods: Current study was an observational, retrospective, non-interventional analysis of voluntarily reported ADRs forms, between April 2018 and January 2020.  All cutaneous ADRs reported within this period were identified. Data obtained were expressed in numbers, percentages.Results: 130 cutaneous ADRs was reported during the period of study. Fixed drug eruptions (30%) was the most common cutaneous reaction. The most common causal drug groups were antimicrobials (58.5%). Amongst antimicrobials, ornidazole (8.5%) was the most common drug. The most common drug in NSAID group was paracetamol (14.6%). The major drug causing ACDRs in our study was Paracetamol (14.6%). Assessment of causality revealed 37.7% were probable and 62.3% were possible reactions. Assessment of severity showed 78.5% as mild and 21.5% as moderate. Assessment of preventability showed that 6.1% probably preventable and 93.9% not preventable.Conclusions: Knowledge of the pattern of cutaneous reactions and the causative drugs guides us in early diagnosis of the condition, better management and associated decrease in morbidity, mortality. In the current study, the most common causal drug group were antimicrobials. The most common morphological pattern and drug causing ACDRs were fixed drug eruptions and paracetamol, respectively

High Prevalence of Abdominal, Intra-Abdominal and Subcutaneous Adiposity and Clustering of Risk Factors among Urban Asian Indians in North India

OBJECTIVE: To assess the prevalence of abdominal obesity including intra-abdominal and subcutaneous adiposity along with other cardiometabolic risk factors in urban Asian Indians living in New Delhi. METHODS: We conducted a cross-sectional epidemiological descriptive study with 459 subjects (217 males and 242 females), representing all socio-economic strata in New Delhi. The anthropometric profile [body mass index (BMI), waist circumference (WC) and skinfold thickness], fasting blood glucose (FBG) and lipid profile were recorded. Percent body fat (%BF), total abdominal fat (TAF), intra-abdominal adipose tissue (IAAT) and subcutaneous abdominal adipose tissue (SCAT) were quantified using predictive equations for Asian Indians. RESULTS: The overall prevalence of obesity was high [by BMI (>25 kg/m(2)), 50.1%]. The prevalence of abdominal obesity (as assessed by WC) was 68.9%, while that assessed by TAF was 70.8%. Increased IAAT was significantly higher in females (80.6%) as compared to males (56.7%) (p = 0.00) with overall prevalence being 69.3%. The overall prevalence of high SCAT was 67.8%, more in males (69.1%) vs. females (66.5%, p = 0.5). The prevalence of type 2 diabetes, the metabolic syndrome and hypertension was 8.5%, 45.3% and 29.2%, respectively. Hypertriglyceridemia, hypercholesterolemia and low levels of HDL-c were prevalent in 42.7%, 26.6% and 37% of the subjects, respectively. The prevalence of hypertriglyceridemia was significantly higher in males (p = 0.007); however, low levels of HDL-c were more prevalent in females as compared to males (p = 0.00). CONCLUSION: High prevalence of generalized obesity, abdominal obesity (by measurement of WC, TAF, IAAT and SCAT) and dysmetabolic state in urban Asian Indians in north India need immediate public health intervention

Uncertainty analysis of cost effectiveness in a tailored intervention to promote screening for colorectal cancer

Background. Screening for colorectal cancer (CRC) is considered cost effective but screening compliance in the US remains low. There have been very few studies on economic analyses of screening promotion strategies for colorectal cancer. The main aim of the current study is to conduct a cost effectiveness analysis (CEA) and examine the uncertainty involved in the results of the CEA of a tailored intervention to promote screening for CRC among patients of a multispeciality clinic in Houston, TX. Methods. The two intervention arms received a PC based tailored program and web based educational information to promote CRC screening. The incremental cost of implementing a tailored PC based program was compared to the website based education and the status quo of no intervention for each unit of effect after 12 months of delivering the intervention. Uncertainty analysis in the point estimates of cost and effect was conducted using nonparametric bootstrapping. Results. The cost of implementing a web based educational intervention was $36.00 per person and the cost of the tailored PC based interactive intervention was$43.00 per person. The additional cost per person screened for the web-based strategy was $2374 and the effect of the tailored intervention was negative

Annals of Library and Information Studies: an analysis of citation pattern

This study based on 2318 citations appended to 106 research articles of the year 2010-2012 of Annals of Library and Information Studies. The authorship pattern shows that 57.7 percent are single-authored, 27.8 percent double- and 10.5 percent triple-authored and the remaining 4.1 percents are joint contributions of four to seven authors. There are 2061 cited authors and nearly 350 cited journals. It is clear that a majority of documents cited in these years were published not more than twenty years ago. The Bradford’s law and Lotka’s law were verified for the cited journals and authors respectively. It has been observed that the respective distribution patterns fairly in consonance with these two bibliometric laws

"Growing Solutions: Evaluating the Impact and Viability of Poshan-Vatika in Combating Anemia among Pregnant Women and Adolescent Girls in Bhanvad Taluka, DevBhoomi Dwarka, Gujarat"

Introduction: Kitchen gardens, as small-scale vegetable cultivation areas within households, play a crucial role in providing a sustainable source of fresh and nutritious vegetables. This study forms a pivotal component of an innovation pilot project where kitchen garden intervention holds significant importance. The primary aim and objectives of this study revolve around assessing the effectiveness and feasibility of the kitchen garden intervention in addressing anemia among pregnant women and adolescent girls in Bhanvad Taluka of Devbhoomi Dwarka, Gujarat. By integrating the cultivation of vegetables within households, the study aims to contribute to improved nutrition and overall wellbeing in these specific demographic groups. Materials and Methods: The current study, conducted between June 2020 to March 2021, focused on Bhanvad Taluka of DevBhoomi Dwarka, Gujarat. Employing a mixed-method approach, the study targeted a sample of 60 pregnant women and 304 adolescent girls, selected through simple random sampling. Verbal informed consent was obtained from each participant to ensure ethical research practices. The evaluation team administered a semistructured, pilot-tested questionnaire in the local language. Counsellors, including FHW/ MS/ FHS/ASHA, actively participated in the project, contributing to the comprehensive nature of the study. Results: Severity of anemia got reduced due to the project interventions. Overall scenario among total beneficiaries at the end of project found that mild cases were increased and moderate cases got reduced while there no change among severe cases reported. Conclusion: The use of Kitchen Garden can promote awareness of the importance of a healthy diet and encourage the consumption of locally grown fruits and vegetables. However, further research is needed to evaluate the effectiveness and feasibility of Kitchen Garden as an intervention to address anemia among pregnant women and adolescent girls