X-ray time lag evaluation of MAXI J1820+070 with a differential cross-correlation analysis

MAXI J1820$+$070 is a transient black hole binary (BHB) discovered on 2018 March 11. The unprecedented rich statistics brought by the NICER X-ray telescope allows detailed timing analysis up to $\sim$1~kHz uncompromised by the photon shot noise. To estimate the time lags, the Fourier analysis was applied, which led to two different conclusions for the system configuration; one supporting the lamp-post configuration with a stable accretion disk extending close to the innermost stable circular orbit and the other supporting the truncated accretion disk contracting with time. Using the same data set, we present the results based on the cross-correlation function (CCF). The CCF is calculated between two different X-ray bands and one side is subtracted from the other side, which we call the differential CCF (dCCF). The soft and hard lags respectively of $\sim$0.03 and 3~s are clearly identified without being diluted by the spectral mixture, demonstrating the effectiveness of the dCCF analysis. The evolution of these lags is tracked, along with spectral changes for the first 120~days since the discovery. Both the dCCF and spectral fitting results are interpreted that the soft lag is a reverberation lag between the Comptonized emission and the soft excess emission and that the hard lag is between the disk black body emission and the Comptonized emission. The evolution of these lags is in line with the picture of the truncated disk contracting with time.Comment: 12 pages, 12 figure

Spectral Modeling of the Supersoft X-ray Source CAL87 based on Radiative Transfer Codes

Super Soft X-ray Sources (SSS) are white dwarf (WD) binaries that radiate almost entirely below $\sim$1~keV. Their X-ray spectra are often complex when viewed with the X-ray grating spectrometers, where numerous emission and absorption features are intermingled and hard to separate. The absorption features are mostly from the WD atmosphere, for which radiative transfer models have been constructed. The emission features are from the corona surrounding the WD atmosphere, in which incident emission from the WD surface is reprocessed. Modeling the corona requires different solvers and assumptions for the radiative transfer, which is yet to be achieved. We chose CAL87, a SSS in the Large Magellanic Cloud, which exhibits emission-dominated spectra from the corona as the WD atmosphere emission is assumed to be completely blocked by the accretion disk. We constructed a radiative transfer model for the corona using the two radiative transfer codes; xstar for a one-dimensional two-stream solver and MONACO for a three-dimensional Monte Carlo solver. We identified their differences and limitations in comparison to the spectra taken with the Reflection Grating Spectrometer onboard the XMM-Newton satellite. We finally obtained a sufficiently good spectral model of CAL87 based on the radiative transfer of the corona plus an additional collisionally ionized plasma. In the coming X-ray microcalorimeter era, it will be required to interpret spectra based on radiative transfer in a wider range of sources than what is presented here.Comment: 15 pages, 15 figures, ApJ in pres

Closure of multiple ventricular septal defects by the felt sandwich technique: Further analysis of 36 patients

ObjectivesWe previously described a novel technique for closure of trabecular ventricular septal defects by sandwiching the septum with 2 polyester felt patches without requiring left ventriculotomy. We describe the midterm results of this technique and the postoperative cardiac function.MethodsThis is a retrospective study of 36 consecutive patients. The median age and body weight at the time of repair was 15 months (range: 2-115 months) and 7.8 kg (range: 3.9-51.9 kg), respectively.ResultsSixty-three trabecular ventricular septal defects in 36 patients were closed with the felt sandwich technique. In the early postoperative period, 1 patient died of pulmonary hypertensive crisis. There were 2 late deaths. One patient died of pneumonia 6 months after surgery, and another died suddenly of ventricular arrhythmias 2 years after surgery. Three patients required reoperation (closure of major residual ventricular septal defect, cardiac transplantation for dilated cardiomyopathy, and pacemaker implantation for complete atrioventricular block). Postoperative left ventricular fractional shortening in the group with a body surface area less than 0.4 m2 was significantly lower than that in the group with a body surface area of 0.4 m2 or greater (0.22 ± 0.09 vs 0.31 ± 0.06, P = .0027). Moreover, there was a strong correlation between postoperative left ventricular ejection fraction and total patch area/body surface area ratio (R = −0.74, P = .0004).ConclusionMultiple trabecular ventricular septal defects can be closed with the felt sandwich technique easily and safely. Although this technique can be used in small infants, the use of numerous felt patches disturbs the movement of ventricular septum, which may cause postoperative cardiac dysfunction

Highly polarized polymer light-emitting diodes utilizing friction-transferred poly(9,9-dioctylfluorene) thin films

Polarized polymer light-emitting diodes (PLEDs) have been constructed utilizing friction-transferred poly(9,9-dioctylfluorene) (PFO) thin films. The friction transfer technique allows oriented PFO to be deposited directly onto an indium tin oxide anode without an alignment layer such as polyimide. Polarized absorption and photoluminescence spectra revealed that the polymer backbones are highly aligned in the friction direction. We fabricated PLEDs consisting of friction-transferred PFO as an emissive layer, vacuum-deposited bathocuproine as an electron transport and hole-blocking layer, and a vacuum-deposited LiF/Al cathode. Highly polarized blue emission with an integrated polarization ratio of 31 and a luminance of up to 300 cd/m2 was observed from the PLEDs

Highly polarized polymer light-emitting diodes utilizing friction-transferred poly(9,9-dioctylfluorene) thin films

Polarized polymer light-emitting diodes (PLEDs) have been constructed utilizing friction-transferred poly(9,9-dioctylfluorene) (PFO) thin films. The friction transfer technique allows oriented PFO to be deposited directly onto an indium tin oxide anode without an alignment layer such as polyimide. Polarized absorption and photoluminescence spectra revealed that the polymer backbones are highly aligned in the friction direction. We fabricated PLEDs consisting of friction-transferred PFO as an emissive layer, vacuum-deposited bathocuproine as an electron transport and hole-blocking layer, and a vacuum-deposited LiF/Al cathode. Highly polarized blue emission with an integrated polarization ratio of 31 and a luminance of up to 300 cd/m2 was observed from the PLEDs

Highly efficient polarized polymer light-emitting diodes utilizing oriented films of beta-phase poly(9,9-dioctylfluorene)

Uniaxially oriented films of beta-phase poly(9,9-dioctylfluorene) (PFO) were realized by a friction-transfer technique followed by thermal annealing and vapor treatments. Absorption and photoluminescence (PL) spectra show the characteristics of beta-phase: an additional absorption peak at 433 nm and redshifted PL peaks compared with those of the usual nematic (N) phase. We fabricated polarized polymer light-emitting diodes utilizing oriented films of beta-phase PFO. Highly polarized beta-phase emission with an integrated polarization ratio of 51 was observed from the devices. The efficiency of the devices based on beta-phase reached 2.0 cd/A, which is two times higher than that based on N-phase

On-line assessment of regional ventricular wall motion by transesophageal echocardiography with color kinesis during minimally invasive coronary artery bypass grafting

AbstractObjective: Our objective was to determine the changes in regional ventricular wall motion during minimally invasive direct coronary artery bypass grafting by color kinesis using transesophageal echocardiography. Methods: Minimally invasive coronary artery bypass grafting was performed in 34 patients, during which transesophageal echocardiography was used. Thirteen patients had isolated disease of the left anterior descending artery. Regional ventricular wall motion was analyzed by color kinesis with the SONOS 2500 transesophageal echocardiograph (Hewlett-Packard Co, Andover, Mass). On-line assessment of regional wall motion was continued during the operation. Results: Wall motion abnormalities during ischemia were present in 4 cases, left ventricular mid-anterior hypokinesis in 3 cases, and left ventricular apical-lateral hypokinesis in 1 case. In all cases, wall motion was maintained after bypass. In patients with total coronary occlusion, changes in wall motion did not occur during anastomosis. Conclusions: Color kinesis allowed us to evaluate the change in regional ventricular wall motion induced by myocardial ischemia during minimally invasive coronary artery bypass grafting both objectively and quantitatively. (J Thorac Cardiovasc Surg 1999;117:912-7

Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome

Flavonoids are a subclass of polyphenols which are attractive, due to possessing various physiological activities, including a radioprotective effect. Tumor suppressor p53 is a primary regulator in the radiation response and is involved in the pathogenesis of radiation injuries. In this study, we revealed that isorhamnetin inhibited radiation cell death, and investigated its action mechanism focusing on DNA damage response. Although isorhamnetin moderated p53 activity, it promoted phosphorylation of ataxia telangiectasia mutated (ATM) and enhanced 53BP1 recruitment in irradiated cells. The radioprotective effect of isorhamnetin was not observed in the presence of ATM inhibitor, indicating that its protective effect was dependent on ATM. Furthermore, isorhamnetin-treated mice survived gastrointestinal death caused by a lethal dose of abdominal irradiation. These findings suggested that isorhamnetin enhances the ATM-dependent DNA repair process, which is presumably associated with the suppressive effect against GI syndrome

Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels

Semen quality is affected by environmental factors, endocrine function abnormalities, and genetic factors. A GWAS recently identified ERBB4 at 2q34 as a genetic locus associated with sperm motility. However, GWASs for human semen volume and sperm concentration have not been conducted. In addition, testis size also reportedly correlates with semen quality, and it is important to identify genes that affect testis size. Reproductive hormones also play an important role in spermatogenesis. To date, genetic loci associated with plasma testosterone, sex hormone-binding globulin (SHBG), follicle stimulating hormone (FSH), and luteinizing hormone (LH) levels have been identified using GWASs. However, GWASs have not identified any relevant loci for plasma inhibin B levels. We conducted a two-stage GWAS using 811 Japanese men in a discovery stage followed by a replication stage using an additional 721 Japanese men. The results of the discovery and replication stages were combined into a meta-analysis. After setting a suggestive significance threshold for P values < 5 × 10-6　in the discovery stage, we identified ten regions with SNPs (semen volume: one, sperm concentration: three, testes size: two, and inhibin B: four). We selected only the most significant SNP in each region for replication genotyping. Combined discovery and replication results in the meta-analysis showed that the locus 12q21.31 associated with plasma inhibin B levels (rs11116724) had the most significant association (P = 5.7 × 10-8). The LRRIQ1 and TSPAN19 genes are located in the 12q21.31 region. This study provides new susceptibility variants that contribute to plasma inhibin B levels