Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients-6

<p><b>Copyright information:</b></p><p>Taken from "Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients"</p><p>http://respiratory-research.com/content/8/1/48</p><p>Respiratory Research 2007;8(1):48-48.</p><p>Published online 6 Jul 2007</p><p>PMCID:PMC1939846.</p><p></p> compared to non-smokers and stage IV COPD (p = 0.009). The post-hoc comparison was significant at 0.05 level between non-smokers and stage I-II COPD (*). B. The mean percentage of GSTO1-1 positive macrophages was higher in severe stage IV COPD compared to smokers or COPD stage I-II (p = 0.004). The difference between non-smokers and other groups was not statistically significant. The post-hoc comparison was significant at 0.05 level between stage IV COPD and smokers and between stage IV and stage I-II COPD (*)

Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients-4

<p><b>Copyright information:</b></p><p>Taken from "Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients"</p><p>http://respiratory-research.com/content/8/1/48</p><p>Respiratory Research 2007;8(1):48-48.</p><p>Published online 6 Jul 2007</p><p>PMCID:PMC1939846.</p><p></p>ents showed an decreased immunoreacitivity in patients with COPD compared to non-smokers (p = 0.023). B. GSTO1-1 could be detected in the plasma samples and bronchoalveolar lavage fluid. Representative Western blots from three non-smokers are shown. C. GSTO1-1 was also expressed in the culture medium of U937 monocytes and BEAS-2B cells. D. Lung tissue homogenates showed higher level of GSTO1-1 in the specimens obtained from non-smokers or smokers with normal lung function when compared to COPD, p = 0.003

The GSTO1-1 immunoreactivity was most prominent in alveolar macrophages varying from negative to moderate/intense and GSTO1-1 expression was either absent or weak in other cell types

<p><b>Copyright information:</b></p><p>Taken from "Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients"</p><p>http://respiratory-research.com/content/8/1/48</p><p>Respiratory Research 2007;8(1):48-48.</p><p>Published online 6 Jul 2007</p><p>PMCID:PMC1939846.</p><p></p> Alveolar epithelium was always positive in stage IV COPD. Bars represent means, error bars standard error of mean