ORAL SQUAMOUS CELL CARCINOMA IN RHESUS MACAQUE (MACACA MULATTA)

This paper describes an oral squamous cell carcinoma with metastases into the lung in a 24-years-old female rhesus macaque (Macaca mulatta). At necropsy, 3.5 cm ulcerative, white grey, irregular mass with necrosis and loss of the muscle, and osteolysis of the mandibular bone was observed on the mentum. Histopathologically, the mass consisted of multiple highly cellular lobules of oval to polygonal cells in the abundant connective tissue stroma, and with high mitotic index. There were multifocal pearl-like foci of keratinized cells. Neoplastic cells were PAS negative. Immunohistochemically, positive labeling for high molecular weight cytokeratine (CKhmw) and negative labeling for CA antigen were obtained. Key words: neoplasia, histopathology, immunohistochemistry, monke

THE FIRST CASE OF MYCOBACTERIUM TERRAE INFECTION IN CATTLE IN BOSNIA AND HERZEGOVINA

We here describe a case of Mycobacterium terrae infection in a cow in a small dairy household. At necropsy of the cow otherwise positive on routine annual tuberculin skin testing, severe multifocal granulomatous dermatitis and panniculitis, and moderate granulomatous (parasitic) colitis were observed. Histopathology revealed granulomatous dermatitis. Bacteria isolated from regional and thoracic lymph nodes, and skin lesions were identified by colony morphology, biochemical testing and molecular methods as M. terrae. Our findings confirm the difficulties that non-tuberculous mycobacteria can cause in vivo diagnosis of mycobacterial infections, especially in conjunction with parasitic infestations. Key words: Cattle, Mycobacterium terrae, Granulomatous dermatitis, Bosnia and Herzegovin

Troglostrongylus brevior in an Eurasian lynx (Lynx lynx) from Bosnia and Herzegovina

Background: In the past few years the interest of the scientific community on lungworms of the genus Troglostrongylus has grown due to the increased number of unexpected cases of infections with Troglostrongylus brevior in domestic cats from Mediterranean Europe, likely due to a spill-over from wild reservoirs. Thus, there is a merit to increase our knowledge on the occurrence of this parasite in felids from European regions. The present paper describes lung lesions associated with T. brevior infection in the endangered Eurasian lynx (Lynx lynx) from Bosnia and Herzegovina. Findings: The carcass of an illegally killed 3-year-old male Eurasian lynx was presented for necropsy at the Faculty of Veterinary Medicine of Sarajevo (Bosnia and Herzegovina). Grossly, multiple, multinodular, consolidated and firm, tan to grey areas, occupying the caudal third of caudal lung lobes, were observed. At cut section, the catarrhal fluid was draining from the airways. Larvae of T. brevior were found in tracheal scraping. The histopathological examination revealed multifocal to coalescing areas, centered on bronchi and bronchioles, and expanded alveoli filled with necrotic debris, degenerated inflammatory cells, mostly neutrophils and macrophages, and multiple cross sections of parasite larvae and thin-walled morulated eggs of lungworms. The paraffin-embedded lung samples were molecularly positive for T. brevior. Conclusion: This paper describes the first record of T. brevior in the Eurasian lynx and the associated host lung pathology. Given its pathogenic potential and the lack of data on troglostrongylosis in lynx populations, the occurrence and impact of Troglostrongylus spp. on wildlife health as well as the role of L. lynx as reservoir of infection for other felids, should be further investigated