Анализ технических средств для измерения параметров кривизны скважины

Магистерская диссертация включает 109 страниц текстового материала, 21 рисунок, 12 таблиц, 45 источников, 4 приложения. Объект исследования: Телеметрическое оборудование для проведения измерений параметров кривизны скважины. Цель работы: разработка методики выбора телеметрической системы дляконкретно заданных геолого-технических условий. Результаты исследования: Основным результатом исследовательской работы является разработка методики выбора телеметрической системы для различных геолого технологических условий. Методы проведения исследования: Был проведен сбор данных практического использования различных телеметрических систем и по результатам проведенного анализа приведены рекомендации по выбору подходящего типа оборудования для различных геолого-технологических условий.Object of research: M/LWD telemetry systems. Results of research: The main result of the research work is the development of a methodology for selecting a telemetry system for various geological and technical conditions. Methods of conducting the research: Oil filed data was collected systems and as a result of a comparative analysis of the data obtained in a table of recommendations

Геология и особенности извлечения урана методом подземного скважинного выщелачивания на месторождение Буденовское (Южный Казахстан)

Эпигенетические месторождения урана региональных зон пластового окисления представлены большой группой месторождений в пределах Шу-Сарысуйской и Сырдарьинской ураново-рудных провинций. Общие ресурсы, заключенные в месторождениях пластово-инфильтрационного типа, весьма значительны и составляют более 75% всех ресурсов урана Республики Казахстан.The Chu-Sarysu Basin is located in south-central Kazakhstan. It is as much as 250 km wide and extends for more than 600 km from the foothills of the Tien Shan mountains to the south and southeast, and merges into the flats of the Aral Sea depression to the northwest. The northern and western boundary coincides roughly with the course of the Sarysu River while the Chu river flows across the southern part of the basin. The basin is bounded to the SW by the NW-SE-trending Karatau mountain range, which separates the Chu-Sarysu Basin from the southwesterly located Syr-Darya Basin. These two basins originally formed a single basin before they were separated by periodical uplift s of the Karatau Range. The separation took place after the formation of the U deposits

Die Rolle des Chemokinrezeptors CXCR3 im Rahmen der akuten und chronischen Leberschädigung

Because of its anatomical localization, the liver plays a very important role during the immune response. It is enriched with various immune cell populations, i.e. macrophages, T-cells or NK-cells. In the same way further immune cells can be recruited from the peripheral blood, which is regulated by a complex chemokine ligand- receptor system. This study investigated the role of the chemokine receptor CXCR3 and its ligands CXCL4, CXCL9, CXCL10 and CXCL11 during acute and chronic liver diseases. Therefore in vivo experiments with CXCR3 knockout mice were applied and the obtained data were verified with human samples and further in vitro experiments. It could be shown that the chemokine receptor CXCR3 is essential for the recruitment of NK- and NKT- cells during the acute CCl4 induced liver injury. The reduced amount of these cells resulted in an augmented necrotic damage which was accompanied by an elevated intrahepatic HMGB1 concentration. This led to an enhanced infiltration of neutrophils into the liver and which than further increased the liver damage. In the second part of this study it was shown that the chemokine CXCL9 and its receptor CXCR3 are important mediators of murine and human HCV induced liver fibrosis. CXCR3 knockout mice developed an enhanced fibrosis, compared to wild type mice, which was associated with a reduced infiltration of IFN-γ producing T-cells. During human HCV induced liver fibrosis the intrahepatic CXCL9 concentration increased with ongoing fibrosis. Additionally it could be proven that the Chemokine CXCL9 acts antifibrotic on stellate cells in vitro. It was also shown that the chemokine CXCL4 and platelets are involved in chronic liver diseases. During human HCV induced fibrosis the platelets are in direct contact to the collagen fibrils and CXCL4 concentration increased with ongoing fibrosis. Additionally it could be proven that the Chemokine CXCL4 acts profibrotic on stellate cells in vitro. The results obtained in this study show an unexpected positive role of the chemokine receptor CXCR3 during acute toxic liver injury, which should be taken into account for future treatments with CXCR3 antagonists. There were also chemokine based antifibrotic pathways described, which could the first steps for potential antifibrotic therapies. Concluding it was proven that platelets play an important role during chronic liver diseases and could be a potential new target for the development of antifibrotic therapies

From Intergovernmental to Global: UNESCO´s Response to Globalization.

Publicado en Review of International Organization, Vol. 2 No. 1, 2007. Diciembre 2006.Whilst there is an ever-growing literature on the economic and political aspects of "globalization", at present there are few studies analyzing how intergovernmental organizataions have reacted to this phenomenon. This article aims to fill this gap by analizing the response to globalization of UNESCO, one of the least studied organization of the UN constellation.Peer reviewe