Flow chart of the study process detailing screen failure rates.

<p>The study screen flow is presented detailing screen failure rates.</p

Theoretical framework used for data collection and analysis as adapted from Van der Straten et al [38] and Merkatz et al [40].

<p>The framework proposed by van der Straten et al [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0199096#pone.0199096.ref035" target="_blank">35</a>] was used for data collection and analysis; elements of the NES/EE CVR acceptability model by Merkatz et al [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0199096#pone.0199096.ref037" target="_blank">37</a>] such as side effect and bodily changes were added.</p

Flow chart of quantitative and qualitative data collection in the Ring Plus study.

<p>Quantitative and qualitative data collected before, during and after study end are presented.</p

Demographic and behavioral characteristics of female sex workers and female VCT clients, Kigali, Rwanda.

<p>Demographic and behavioral characteristics of female sex workers and female VCT clients, Kigali, Rwanda.</p

CD4 count distribution among HIV-positive female sex workers and female VCT clients in Kigali, Rwanda.

<p>CD4 count distribution among HIV-positive female sex workers and female VCT clients in Kigali, Rwanda.</p

Factors associated with prevalent and recent HIV infection among female sex workers, Kigali, Rwanda.

<p>Factors associated with prevalent and recent HIV infection among female sex workers, Kigali, Rwanda.</p

Factors associated with prevalent and recent HIV infection among female VCT clients, Kigali, Rwanda.

<p>Factors associated with prevalent and recent HIV infection among female VCT clients, Kigali, Rwanda.</p

Laboratory-confirmed bacterial vaginosis, vaginal yeasts and trichomoniasis by randomisation group.

<p>Laboratory-confirmed bacterial vaginosis, vaginal yeasts and trichomoniasis by randomisation group.</p

Spontaneously reported¹ adverse events: comparison by group for the total ring use period and per 100 used rings.

<p>Spontaneously reported<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0197572#t004fn002" target="_blank">¹</a> adverse events: comparison by group for the total ring use period and per 100 used rings.</p

Baseline characteristics of the screened population and enrolled population by randomisation group.

<p>Baseline characteristics of the screened population and enrolled population by randomisation group.</p