1 research outputs found
Preparation of <i>N</i>‑Linked-Type GlcNAc Monomers for Glycopolymers and Binding Specificity for Lectin
Glycomonomers having N-glycosidic linkages
were
prepared from a known glycosyl amine, N-acetyl-d-glucosamine (GlcNAc). Radical polymerization of the glycomonomers
gave a series of glycopolymers displaying various sugar densities,
which were models of the core structure of Asn-linked-type glycoproteins.
In addition, fluorometric analyses of wheat germ agglutinin (WGA)
against the glycopolymers were carried out, and the results showed
unique binding specificities on the basis of flexibility of sugar
moieties