11 research outputs found
Geological distribution of the number of reported PTB in Xinjiang, China (2011 and 2015).
<p>*Note: A is for 2011, and B is for 2015.</p
Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
<div><p>Background</p><p>Despite the reduction in reported incidence of tuberculosis globally, the burden of pulmonary tuberculosis (PTB) remains high in low- and middle- income countries, including China. The current study aims to evaluate the distribution and trend of PTB incidence in Xinjiang, the region with the highest PTB burden in China.</p><p>Methods</p><p>We identified all confirmed PTB case records reported to the Chinese TB Information Management System (TBIMS) between 2011 and 2015. We analyzed these records to measure the annual incidence of reported smear-positive PTB cases in Xinjiang and its trend over time. We also analyzed incidence by gender, residential area, and region. Spatial analysis was used to describe the inter-regional disparity of the disease burden during the study period.</p><p>Results</p><p>We identified 212,216 smear-positive PTB cases between 2011 and 2015. The reported incidence increased from 180.8 cases in 2011 to 195.8 cases in 2015 per 100,000 population. The southern region of Xinjiang had the highest disease burden (257.8/100,000 in 2011 and 312.7/100,000 in 2015). More than 60% cases occurred in persons >45 years, and 76% of cases lived in rural areas.</p><p>Conclusion</p><p>To reach the goal of elimination and control of TB, more comprehensive STOP TB strategies should be implemented in Xinjiang. Residents in the southern region and rural areas of Xinjiang require particular attention.</p></div
Distribution of the yearly reported pulmonary tuberculosis cases in Xinjiang Uygur Autonomous Region, China, 2011–2015.
<p>Distribution of the yearly reported pulmonary tuberculosis cases in Xinjiang Uygur Autonomous Region, China, 2011–2015.</p
Population level occurrence and trend of pulmonary tuberculosis in Xinjiang Uygur Autonomous Region, China, 2011–2015.
<p>Population level occurrence and trend of pulmonary tuberculosis in Xinjiang Uygur Autonomous Region, China, 2011–2015.</p
Prevalence of ATLI in patients according to acetylator status.
#<p>Cochrane-Armitage test for trend.</p
Definition of acetylator status according to NAT2 genotypes.
<p>Definition of acetylator status according to NAT2 genotypes.</p
Genetic polymorphisms of CYP2E1,GSTM1 and GSTT1 and the prevalence of ATLI.
*<p>Cochrane-Armitage test.</p
Incidence of ATLI in patients tested at 2 months.
1<p>ALT, AST or bilirubin more than twice the upper limit of the normal range.</p>2<p>ALT, AST or bilirubin above the upper limit of the normal range and less than twice the upper limit of normal.</p>3<p>ALT, AST and bilirubin within the normal range.</p