Coupled rotor-body vibrations with inplane degrees of freedom

In an effort to understand the vibration mechanisms of helicopters, the following basic studies are considered. A coupled rotor-fuselage vibration analysis including inplane degrees of freedom of both rotor and airframe is performed by matching of rotor and fuselage impedances at the hub. A rigid blade model including hub motion is used to set up the rotor flaplag equations. For the airframe, 9 degrees of freedom and hub offsets are used. The equations are solved by harmonic balance. For a 4-bladed rotor, the coupled responses and hub loads are calculated for various parameters in forward flight. The results show that the addition of inplane degrees of freedom does not significantly affect the vertical vibrations for the cases considered, and that inplane vibrations have similar resonance trends as do flapping vibrations

New results for the missing quantum numbers labeling the quadrupole and octupole boson basis

The many $2^k$-pole boson states, $|N_kv_k\alpha_k I_kM_k>$ with $k=2,3$, realize the irreducible representation (IR) for the group reduction chains $SU(2k+1)\supset R_{2k+1}\supset R_3\supset R_2$. They have been analytically studied and widely used for the description of nuclear systems. However, no analytical expression for the degeneracy $d_v(I)$ of the $R_{2k+1}$'s IR, determined by the reduction $R_{2k+1}\supset R_3$, is available. Thus, the number of distinct values taken by $\alpha_k$ has been so far obtained by solving some complex equations. Here we derive analytical expressions for the degeneracy $d_v(I)$ characterizing the octupole and quadrupole boson states, respectively. The merit of this work consists of the fact that it completes the analytical expressions for the $2^k$-pole boson basis.Comment: 10page

Decoherence of two qubits in a non-Markovian reservoir without rotating-wave approximation

The decoherence of two initially entangled qubits in a non-Markovian reservoir has been investigated exactly without Born Markovian approximation and rotating-wave approximation(RWA). The non-perturbative quantum master equation is derived and its exact solution is obtained. The decoherence behaviors of two qubits, initially entangled in Bell states, has been investigated in three different cases of parameters. The results show that the counter-rotating wave terms have great influence on the decoherence behavior, and there are differences between the exact solution of the Hamiltonian with RWA and that of the exact Hamiltonian without RWA. It might be improper to take RWA when the atom is in a non-markovian reservoir

A Comparison of Murine Smooth Muscle Cells Generated from Embryonic versus Induced Pluripotent Stem Cells

Smooth muscle cell (SMC) differentiation and dedifferentiation play a critical role in the pathogenesis of cardiovascular diseases. The lack of a good and simple in vitro SMC differentiation system has hampered the progress of SMC field for years. The generation of such an in vitro system would be invaluable for exploring molecular mechanisms of SMC differentiation and dedifferentiation. Recently, the establishment of induced pluripotent stem (iPS) cells has offered a novel therapeutic strategy to generate patient-specific stem cell lines. Here we have investigated whether iPS cells are able to differentiate into SMCs in vitro. Mouse iPS cell (O9 and TT025) monolayers were treated with 105 mol/L all-trans retinoid acid (RA). After 8 days of RA treatment, we found that >40% of the O9 iPS cells expressed the SMC-markers including SMα-actin and SM myosin heavy chain. Also, we documented that iPS-derived SMCs acquired SMC functional characteristics including contraction and calcium influx in response to stimuli. Moreover, our results indicated that there were differences in SMC-specific gene expression patterns between SMCs derived from O9 and TT025 iPS as well as normal embryonic stem cells. These differences might be due to disparity in the current iPS technology. Taken together, our data have established a simple iPS-SMC system to generate SMCs in vitro, which has tremendous potential to generate individualized SMCs for vascular tissue engineering and personalized drug screening.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78153/1/scd.2008.0179.pd

Method of determining cosmological parameter ranges with samples of candles with an intrinsic distribution

In this paper, the effect of the intrinsic distribution of cosmological candles is investigated. We find that, in the case of a narrow distribution, the deviation of the observed modulus of sources from the expected central value could be estimated within a ceratin range. We thus introduce a lower and upper limits of $\chi ^{2}$, $\chi_{\min}^{2}$ and $\chi_{\max}^{2}$, to estimate cosmological parameters by applying the conventional minimizing $\chi ^{2}$ method. We apply this method to a gamma-ray burst (GRB) sample as well as to a combined sample including this GRB sample and an SN Ia sample. Our analysis shows that: a) in the case of assuming an intrinsic distribution of candles of the GRB sample, the effect of the distribution is obvious and should not be neglected; b) taking into account this effect would lead to a poorer constraint of the cosmological parameter ranges. The analysis suggests that in the attempt of constraining the cosmological model with current GRB samples, the results tend to be worse than what previously thought if the mentioned intrinsic distribution does exist.Comment: 6 pages,4 figures,1 tables.Data updated. Main conclusion unchange

Differential Presentations of Arterial Thromboembolic Events Between Venous Thromboembolism and Atrial Fibrillation Patients

Objective: Atrial fibrillation (AF) and venous thromboembolism (VTE) share several risk factors related to arterial thromboembolism. No study has reported the differential contribution to arterial thromboembolic events and mortality between these two conditions in the same population. We therefore assessed the differential arterial thromboembolic events between AF and VTE. Methods: We included AF and VTE national cohorts derived from Taiwan National Health Insurance Research Database between 2001 and 2013. The eligible population was 314,861 patients in the AF cohort and 41,102 patients in the VTE cohort. The primary outcome was arterial thromboembolic events, including ischemic stroke, extracranial arterial thromboembolism (ECATE) and myocardial infarction (MI). Secondary outcomes were all-cause mortality and cardiovascular death. Results: After a 1:1 propensity matching, 32,688 patients in either group were analyzed. The risk of arterial thromboembolic events was lower in the VTE cohort than that in the AF cohort (subdistribution hazard ratio [SHR], 0.60; 95% confidence interval [CI], 0.57–0.62). The risk of ischemic stroke (SHR, 0.44; 95% CI, 0.42–0.46) and MI (SHR, 0.80; 95% CI, 0.72–0.89) were lower in the VTE cohort, while the risk of ECATE (SHR, 1.23; 95% CI, 1.14–1.33; particularly lower extremities) was higher in the VTE cohort. All-cause mortality rate was higher in the VTE cohort (HR, 1.18; 95% CI, 1.15–1.21) while the risk of cardiovascular death was lower in the VTE cohort (HR, 0.96; 95% CI, 0.93–0.995). Conclusions: Patients with AF had higher risks of arterial thromboembolic events compared to patients with VTE, despite having risk factors in common. The VTE cohort had higher risks of all-cause mortality and ECATE, particularly lower extremity events, compared to AF patients. The differential manifestations of thromboembolism sequelae and mortality between AF and VTE patients merit further investigation