Estimation of Extreme Wind Speeds with Consideration of Wind Directionality for Typhoon-prone Areas

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Discussion on the Applicability of Using RDT to Identify the Aerodynamic Damping under Vortex-Induced Resonance

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Large Eddy Simulation of Flow around Two Adjacent Tall Buildings

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Field Measurements of Wind-induced Responses of Shanghai World Financial Center: Investigation of Amplitude-dependent Damping

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Large Eddy Simulations of Blockage Ratio Effect on a Square Cylinder In a Uniform Flow

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

A New Quasi-Steady Model for Magnus Effect of Rectangular Plate Windborne Debris

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Aeroelastic Model Test and Field Measurement of 40-m High Lattice Tower

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

Influence of Wind Direction on Wind-induced response of Tall Buildings with rectangular Section

This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017

FAD shows synergistic effect with 5-FU and Bortezomib in killing breast cancer cells.

<p>(A) Cell death of MDA-MB-231 cells treated with 0, 10, 25, 50 and 100 uM of 5-FU was measured by Annexin V and PI assay with or without 1 uM of FAD; (B) Cell death of MDA-MB-231 cells treated with 0, 10, 20, 30 and 40 nM of Bortezomib (BZR) was measured by Annexin V and PI assay with or without 1 uM of FAD. The data were collected from at least three independent experiments. Values are presented as mean ± S.D. **p<0.01.</p

Autophagy contributes to FAD-induced cell death in breast cancer cells.

<p>(A) Cell death of MDA-MB-231 cells treated with 6 uM of FAD with or without 100 uM of Z-VAD-fmk (Z-VAD); (B) Cell death of MDA-MB-231 cells treated with 6 uM of FAD with or without 40 uM of Necrostatin-1 (Nec-1); (C-E) Cell death of MDA-MB-231 (C), MDA-MB-468 (D) and SKBR3 (E) cells treated with 6 uM of FAD with or without 20 uM of chloroquine (CQ); (F) Cell death of MDA-MB-231 cells treated with 6 uM of FAD with or without 5 mM of 3-methyladenine (3-MA); (G) and (H) The western blot analyzed the level of LC3A/B-II/I in the presence of 6 uM FAD for indicated hours in MDA-MB-231 (G), MDA-MB-468 and SKBR3 (H) cells. The level of β-Actin was served as a loading control; (I) The calculated relative ratio of LC3A/B-II/I in breast cancer cells basing on band intensity. The data were collected from at least three independent experiments; (J) Sequence analysis of indel mutations in targeted regions of Atg3 locus in MDA-MB-231 cell clones. sgRNA sequences is shown in light gray shadow and the PAM sequence is in dark gray shadow. Deleted sequence is shown in dashed line; (K) The western blot analyzed the level of ATG3 in single Atg3 CRISPR clones with wild type (WT) and empty vector targeted (gV) cells as controls; (L) The western blot analyzed the level of LC3A/B-II/I in the presence of 6 uM FAD for indicated hours in Atg3 CRISPR clones. The level of β-Actin was served as a loading control; (M) Cell death of MDA-MB-231 wild type cells and Atg3 CRISPR clones was measured by Annexin V and PI assay with or without FAD. The data were collected from at least three independent experiments. Values are presented as mean ± S.D. **p<0.01.</p