Data File 1.csv

Data measured by the synchronized double-scanning method and the μ-PCD method

Supplementary document for Time-resolved photoconductivity distribution measurement by a synchronized double-scanning method - 6123761.pdf

Supplement

Supplementary document for Time-resolved photoconductivity distribution measurement by a synchronized double-scanning method - 6054752.pdf

Supplement

sj-pdf-1-jao-10.1177_03913988221126728 – Supplemental material for Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study

Supplemental material, sj-pdf-1-jao-10.1177_03913988221126728 for Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study by Lu Li, Ming Bai, Qiaona Zhang and Shiren Sun in The International Journal of Artificial Organs</p

Structurally diverse lignans from <i>Solanum lyratum</i>: chemical evidence for their acetylcholinease inhibitory activity

A chemical investigation of Solanum lyratum Thumb. (Solanace) afforded two new lignans (1b and 3) and eleven known lignan analogues (1a, 2a/2b and 4–11). Compounds 1a/1b and 2a/2b were separated as two pairs of enantiomers by chiral high-performance liquid chromatography (HPLC). Their structures were elucidated by detailed spectroscopic and comparative literature data analysis. The absolute configurations of compounds 1a/1b and 2a/2b were determined by comparing the experimental ECD data with the calculated values. All compounds were evaluated for their acetylcholinesterase (AChE) inhibitory activity. Notably, compared to the positive control, compounds 4 and 9 showed obvious AChE inhibition with their IC50 values of 1.30 ± 0.25 and 0.89 ± 0.04 μM, respectively. In addition, the possible interaction between acetylcholinesterase and the active compounds was also investigated by molecular docking.</p

†Electrorubesopsinae, a new subfamily from Cretaceous Burmese amber, as the possible sister group of Dynamopodinae (Coleoptera: Scarabaeidae)

<p>A new subfamily of Scarabaeidae, †Electrorubesopsinae Bai & Wang subfam. nov., is described from Cretaceous amber of Myanmar (earliest Cenomanian, ∼100 Ma) as the possible sister group of Dynamopodinae. †<i>Electrorubesopsis beuteli</i> Bai & Wang gen. et sp. nov. is the first species of this subfamily, which has probably been long extinct. Its external morphology was analysed and compared with all known genera of Dynamopodinae. A phylogenetic analysis based on 82 morphological characters suggests its placement in a sister relationship between †<i>Electrorubesopsis</i> and <i>Orubesa</i>. The hypothesis of a close relationship between <i>Orubesa</i> (Dynamopodini) and <i>Thinorycter</i> (Thinorycterini) is challenged. †<i>Electrorubesopsis</i> likely lived in a sandy environment or forest.</p> <p><a href="http://zoobank.org/urn:lsid:zoobank.org:pub:15351B5E-337C-49D4-90F0-619269BD1E5A" target="_blank">http://zoobank.org/urn:lsid:zoobank.org:pub:15351B5E-337C-49D4-90F0-619269BD1E5A</a></p

Additional file 1: Table S1. of Effect of intracoronary agents on the no-reflow phenomenon during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: a network meta-analysis

Subgroup analysis for select based on the type of control group across trials. Figure S1. Summary forest plot table for the outcome of major adverse cardiovascular events during short term follow-up (≤ 4.5 months). Figure S2. Summary forest plot table for the outcome of major adverse cardiovascular events during long-term follow-up (> 4.5 months). Figure S3. Summary forest plot table for the outcome of major adverse cardiovascular events defined as a composite of death, reincarnation or revascularization. (PDF 1005 kb

Additional file 2: of Mandible evolution in the Scarabaeinae (Coleoptera: Scarabaeidae) and adaptations to coprophagous habits

3D mandible model in 3D PDF of the Scarabaeinae: Kheper devotus. 3D mandible model in 3D PDF of the Dynastinae: Allomyrina dichotoma. 3D mandible model in 3D PDF of the Trogidae: Trox sp. (ZIP 30884 kb

Cytotoxic lignans from the barks of <i>Juglans mandshurica</i>

<p>Phytochemical investigation of the barks of <i>Juglans mandshurica</i> Maxim led to the isolation, purification, and identification of one new lignan named Juglansol A (<b>1</b>), along with nine known compounds (<b>2–10</b>). Their structures were determined by the results of UV, IR, CD, HRESIMS, 1D, and 2D NMR spectroscopic analysis. Compounds <b>1–10</b> were evaluated for their cytotoxicities against A549, HepG2, Hep3B, Bcap-37, and MCF-7 cell lines. The results showed that compound <b>2</b> possessed stronger cytotoxicities against the tested tumor cell lines compared with positive control 5-fluorouracil.</p

Expanded Application of Piper nigrum: Guided Isolation of Alkaloids with Inhibitory Activities of AChE/BuChE and Aβ Aggregation

Piper nigrum is a popular crop that can be used as seasoning or as an additive but its active ingredients also have an effect on the nervous system. Nineteen new amide alkaloids (1a/1b, 2–5, 6a/6b, 7, 8a/8b, 9, 10a/10b, 11a–11b, 12–14) were isolated from P. nigrum, guided by inhibitory activity of AChE and LC–MS/MS based on GNPS. The configurations were determined by extensive spectral analysis, Bulkiness rule, and NMR calculations. The inhibitory activities of AChE/BuChE and Aβ aggregation were tested, and the results showed compounds 2, 7, and 12 had significant inhibitory activities. These components were identified in the crude fraction and their relative quantities were tested, which suggested that compound 2 was the index component in the active site from P. nigrum