101 research outputs found
PediDraw: A web-based tool for drawing a pedigree in genetic counseling-0
<p><b>Copyright information:</b></p><p>Taken from "PediDraw: A web-based tool for drawing a pedigree in genetic counseling"</p><p>http://www.biomedcentral.com/1471-2350/8/31</p><p>BMC Medical Genetics 2007;8():31-31.</p><p>Published online 8 Jun 2007</p><p>PMCID:PMC1904184.</p><p></p> graph connected by the relationship lines. The symbols used in this graph are accepted in a standardized pedigree as described by Bennett, et al. [1
Flowchart of PPI Finder system.
<p>PPI Finder system includes two modules: Information Retrieval (IR module) and Information Extraction (IE module). The relationships of the tables and the data structures are described in the text.</p
Demonstration of the output results of PPI Finder.
<p>Step 1: Our favourite protein name “dysbindin” is searched by selecting “Gene Name”. Step 2: Three results of “dysbindin” are returned. The first row showing “DTNBP1” is the one that unifies the protein name to a unique gene ID. Step 3: By clicking the “DTNBP1” gene, the gene-centred page is shown. The summary of the information of the “DTNBP1” gene is shown on the top. Step 4: The 35 co-occurred genes and their co-occurrence times, PPI database evidences, and gene ontologies are shown at the bottom of the gene-centred page with the co-occurred GO terms highlighted. Step 5: By clicking the hyperlink to “5” in the column of “co-occurrence times” of the fourth co-occurred “SNAPIN” gene, it prompts the co-occurred abstracts and the highlighted words of interaction extraction in the abstracts.</p
Architecture of the backend and frontpage of PPI Finder.
<p>The backend depicts the structure of IR module as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004554#pone-0004554-g001" target="_blank">figure 1</a>. The frontpage of PPI Finder includes two web applications: PPI Finder (searching one gene at a time) and Paired-PPI Finder (searching two genes at a time). The output format of PPI Finder is summarized.</p
Spontaneous Uphill Movement and Self-Removal of Condensates on Hierarchical Tower-like Arrays
Fast
removal of condensates from surfaces is of great significance
due to the enhanced thermal transfer coefficient and continuous condensation.
However, the lost superhydrophobicity of lotus leaves intrigues us
to determine what kind of surface morphologies meets the self-removal
of condensates? The uphill movement of condensates in textured surfaces
is vital to avoid flooding and facilitating self-removal. Here, superhydrophobic
microtower arrays were designed to explore the spontaneous uphill
movement and Wenzel to Cassie transition as well as the self-removal
of condensates. The tower-like arrays enable spontaneous uphill movement
of tiny condensates entrapped in microstructures due to the large
upward Laplace pressure, which is ∼30 times larger than that
on cone-like arrays. The sharp tips decrease the adhesion to suspending
droplets and promote their fast self-removal. These results are important
for designing desirable textured surfaces by enlarging upward Laplace
pressure to facilitate condensate self-removal, which is widely applied
in self-cleaning, antifogging, anti-icing, water harvesting, and thermal
management systems
Three-Dimensional Crystalline/Amorphous Co/Co<sub>3</sub>O<sub>4</sub> Core/Shell Nanosheets as Efficient Electrocatalysts for the Hydrogen Evolution Reaction
Earth-abundant,
low-cost electrocatalysts with outstanding catalytic activity in the
electrochemical hydrogen evolution reaction (HER) are critical in
realizing the hydrogen economy to lift our future welfare and civilization.
Here we report that excellent HER activity has been achieved with three-dimensional core/shell Co/Co<sub>3</sub>O<sub>4</sub> nanosheets composed of a metallic cobalt core
and an amorphous cobalt oxide shell. A benchmark HER current density
of 10 mA cm<sup>–2</sup> has been achieved at an overpotential
of ∼90 mV in 1 M KOH. The excellent activity is enabled with
the unique metal/oxide core/shell structure, which allows high electrical
conductivity in the core and high catalytic activity on the shell.
This finding may open a door to the design and fabrication of earth-abundant,
low-cost metal oxide electrocatalysts with satisfactory hydrogen evolution
reaction activities
- …