75 research outputs found

    A New Band System of the Dicarbon Molecule in the Vacuum Ultraviolet Region

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    As one of the most abundant molecules in the universe, the long history of spectroscopic studies of the dicarbon molecule, C2, reaches back two centuries. While many electronic band systems with upper states below the lowest dissociation threshold have been well characterized, much less is known about transitions to higher-lying states. Here, we report the observation of a new band system of C2 from the lowest triplet state a3Πu through a resonance-enhanced multiphoton ionization scheme. The upper state is identified as 13Σg+, which is determined to be 61539.0 cm–1 (7.630 eV) above ground state X1Σg+. The spectroscopic parameters determined for the 13Σg+ state are in excellent agreement with those predicted by the high-level ab initio calculations. This study paves the way for systematic investigations of the photoabsorption and photodissociation of C2 in the vacuum ultraviolet region, which has important applications in the field of astrochemistry

    Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer-1

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    Reference to the standard curve, as described in methods. The copy number of each mRNA was further normalized as the ratio to the copy number of in all samples. For each gene marker, when the copy number was less than 100, it could not be detectable as a negative case. All the negative results of each indicated gene were shown as number undetected. The median is marked as "" in each group. Where the frequency of negative cases is > 50%, the median cannot be shown.<p><b>Copyright information:</b></p><p>Taken from "Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer"</p><p>http://www.biomedcentral.com/1471-2407/8/156</p><p>BMC Cancer 2008;8():156-156.</p><p>Published online 31 May 2008</p><p>PMCID:PMC2424066.</p><p></p

    Engineering Band Structure via the Site Preference of Pb<sup>2+</sup> in the In<sup>+</sup> Site for Enhanced Thermoelectric Performance of In<sub>6</sub>Se<sub>7</sub>

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    Although binary In–Se based alloys have in recent years gained interest as thermoelectric (TE) candidates, little attention has been paid to In<sub>6</sub>Se<sub>7</sub>-based compounds. Substituting Pb in In<sub>6</sub>Se<sub>7</sub>, preference for Pb<sup>2+</sup> in the In<sup>+</sup> site has been observed, allowing Fermi level (<i>F</i><sub>r</sub>) shift toward the conduction band, where the localized state conduction becomes dominant. Consequently, the Hall carrier concentration (<i>n</i><sub>H</sub>) has been significantly enhanced with the highest <i>n</i><sub>H</sub> value being about 2–3 orders of magnitude higher than that of the Pb-free sample. Meanwhile, the lattice thermal conductivity (κ<sub>L</sub>) tends to be reduced as the <i>n</i><sub>H</sub> value increases, owing to an increased phonon scattering on carriers. As a result, a significantly enhanced TE performance has been achieved with the highest TE figure of merit (ZT) of 0.4 at ∼850 K. This ZT value is 27 times that of intrinsic In<sub>6</sub>Se<sub>7</sub> (ZT = 0.015 at 640 K), which proves a successful band structure engineering through site preference of Pb in In<sub>6</sub>Se<sub>7</sub>

    Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer-2

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    Reference to the standard curve, as described in methods. The copy number of each mRNA was further normalized as the ratio to the copy number of . For each gene marker, when the copy number was less than 100, it could not be detectable as a negative case. All the negative results of each indicated gene were shown as number undetected. The median is marked as "" in each group. Where the frequency of negative cases is > 50%, the median cannot be shown. The K Independent Samples Test (Media Test) was used to analyze gene expression levels among NSCLC patients at different pathologic stages. P < 0.05 (2-tailed test) was considered significant.<p><b>Copyright information:</b></p><p>Taken from "Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer"</p><p>http://www.biomedcentral.com/1471-2407/8/156</p><p>BMC Cancer 2008;8():156-156.</p><p>Published online 31 May 2008</p><p>PMCID:PMC2424066.</p><p></p

    Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer-3

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    Erence to the standard curve, as described in methods. The copy number of each mRNA was further normalized as the ratio to the copy number of . For each gene marker, when the copy number was less than 100, it could not be detectable as a negative case. All the negative results of each indicated gene were shown as number undetected. The median is marked as "" in each group. Where the frequency of negative cases is > 50%, the median cannot be shown. The Mann-Whitney U Test was used to compare the gene expression levels between NSCLC and tuberculo pleurisy groups. P < 0.05 (2-tailed test) was considered significant.<p><b>Copyright information:</b></p><p>Taken from "Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer"</p><p>http://www.biomedcentral.com/1471-2407/8/156</p><p>BMC Cancer 2008;8():156-156.</p><p>Published online 31 May 2008</p><p>PMCID:PMC2424066.</p><p></p

    Multivariate logistic regression analysis of potential risk factors in relation to prevalence of dental caries in an elderly population aged 65–74 years in northeast China.

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    *<p>P<0.05;</p>**<p>P<0.01.</p><p>Abbreviations: β, regression coefficient; S.E., standard error; OR, odds ratio; CI, confidence interval.</p

    Prevalence of dental caries in an elderly population aged 65–74 years old in northeast China.

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    *<p>P<0.05 and</p>**<p>P<0.01, compared with rural areas.</p><p>Abbreviations: DT, decayed tooth; MT, missing tooth; FT, filled tooth; DMFT, decayed, missing, and filled tooth; DFT, decayed and filled tooth; S.D., standard deviation.</p

    Actin Stabilization by Jasplakinolide Affects the Function of Bone Marrow-Derived Late Endothelial Progenitor Cells

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    <div><h3>Background</h3><p>Bone marrow-derived endothelial progenitor cells (EPCs), especially late EPCs, play a critical role in endothelial maintenance and repair, and postnatal vasculogenesis. Although the actin cytoskeleton has been considered as a modulator that controls the function and modulation of stem cells, its role in the function of EPCs, and in particular late EPCs, remains poorly understood.</p> <h3>Methodology/Principal Finding</h3><p>Bone marrow-derived late EPCs were treated with jasplakinolide, a compound that stabilizes actin filaments. Cell apoptosis, proliferation, adhesion, migration, tube formation, nitric oxide (NO) production and endothelial NO synthase (eNOS) phosphorylation were subsequently assayed in vitro. Moreover, EPCs were locally infused into freshly balloon-injured carotid arteries, and the reendothelialization capacity was evaluated after 14 days. Jasplakinolide affected the actin distribution of late EPCs in a concentration and time dependent manner, and a moderate concentration of (100 nmol/l) jasplakinolide directly stabilized the actin filament of late EPCs. Actin stabilization by jasplakinolide enhanced the late EPC apoptosis induced by VEGF deprivation, and significantly impaired late EPC proliferation, adhesion, migration and tube formation. Furthermore, jasplakinolide attenuated the reendothelialization capacity of transplanted EPCs in the injured arterial segment in vivo. However, eNOS phosphorylation and NO production were increased in late EPCs treated with jasplakinolide. NO donor sodium nitroprusside (SNP) rescued the functional activities of jasplakinolide-stressed late EPCs while the endothelial NO synthase inhibitor L-NAME led to a further dysfunction induced by jasplakinolide in late EPCs.</p> <h3>Conclusions/Significance</h3><p>A moderate concentration of jasplakinolide results in an accumulation of actin filaments, enhancing the apoptosis induced by cytokine deprivation, and impairing the proliferation and function of late EPCs both in vitro and in vivo. NO donor reverses these impairments, suggesting the role of NO-related mechanisms in jasplakinolide-induced EPC downregulation. Actin cytoskeleton may thus play a pivotal role in regulating late EPC function.</p> </div

    Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer-0

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    Rated by electrophoresis and visualized in ethidium bromide-stained agarose gels. PB = Peripheral blood; PF = Pleural fluid.<p><b>Copyright information:</b></p><p>Taken from "Diagnostic utility of mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer"</p><p>http://www.biomedcentral.com/1471-2407/8/156</p><p>BMC Cancer 2008;8():156-156.</p><p>Published online 31 May 2008</p><p>PMCID:PMC2424066.</p><p></p
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