834 research outputs found
The Effects of Color Enhanced Information Presentations
Color coding is becoming an important dimension in the presentation mode capabi lity of many information systems. Although color coded output, either alphanumeric or graphic, is of considerable intuitive appeal, there is litt le experimental data on its use or effects. An experimeent is reported which focuses on the effects of color enhanced information presentations. Information is presented to two groups of subjects differing the presentation mode only along the dimension of color coding. The subjects are later tested on the material presented. Analysis of the test results indicates a significant difference in the subjects\u27 performance which is apparently attributable to the color coding of the presentation materials. Directions for further investigations are suggested
Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation
Mode-by-mode summation for the zero point electromagnetic energy of an infinite cylinder
Using the mode-by-mode summation technique the zero point energy of the
electromagnetic field is calculated for the boundary conditions given on the
surface of an infinite solid cylinder. It is assumed that the dielectric and
magnetic characteristics of the material which makes up the cylinder
and of that which makes up the surroundings obey the relation . With this
assumption all the divergences cancel. The divergences are regulated by making
use of zeta function techniques. Numerical calculations are carried out for a
dilute dielectric cylinder and for a perfectly conducting cylindrical shell.
The Casimir energy in the first case vanishes, and in the second is in complete
agreement with that obtained by DeRaad and Milton who employed a Green's
function technique with an ultraviolet regulator.Comment: REVTeX, 16 pages, no figures and tables; transcription error in
previous version corrected, giving a zero Casimir energy for a tenuous
cylinde
Direct mode summation for the Casimir energy of a solid ball
The Casimir energy of a solid ball placed in an infinite medium is calculated
by a direct frequency summation using the contour integration. It is assumed
that the permittivity and permeability of the ball and medium satisfy the
condition . Upon deriving the general
expression for the Casimir energy, a dilute compact ball is considered
. In this case the
calculations are carried out which are of the first order in and take
account of the five terms in the Debye expansion of the Bessel functions
involved. The implication of the obtained results to the attempts of explaining
the sonoluminescence via the Casimir effect is shortly discussed.Comment: REVTeX, 7 pages, no figures and tables, treatment of a dilute
dielectric ball is revised, new references are adde
Structural Characteristics of Polycyclic Aromatic Hydrocarbon Isomers in Coal Tars and Combustion Products
4 Isomeric polycyclic aromatic hydrocarbons (PAH) with two to six rings in coal-derived products and in a carbon black were separated, identified, and quantified by using capillary column gas chromatography and gas chromatography-mass spectrometry. A newly synthesized smectic liquid-crystalline polysiloxane and a conventional polymethylsiloxane were utilized as stationary phases. Many previously difficult to separate isomeric PAH (i.e., methylphenanthrenes/methylanthracenes, triphenylene/ chrysene, methylchrysenes, benzofluoranthenes, and pentaphene/benzo[b]chrysene) were identified. The relative abundances of the PAH in these samples were compared and correlated to the reaction conditions during their production. The relationship between abundance and structure for the identified PAH was also discussed. Introduction Coal-derived products and thermally cracked petroleum oils are highly aromatic in nature and contain polycyclic aromatic hydrocarbons (PAH) as major components. Although average descriptive parameters are usually obtained for such materials (i.e., distillation curve, molecular weight range, aromaticity, etc.), it is oftentimes very important to obtain detailed compositional and structural information. Many of the PAH are toxic and/or mutagenic in various biological test systems. The toxicities of various PAH are related to specific structures and positions of ring substitution. The methylphenanthrene and methylchrysene isomers are typical examples. The 1-and 9-methylphenanthrenes are mutagenic, while the other isomers are inactive ( I ) , and 5-methylchrysene is one of the strongest carcinogens, while the other isomers are only moderately carcinogenic (2). Isomeric parent PAH may differ markedly in their activities; benzo[a]pyrene has significantly greater carcinogenicity than benzo[e]pyrene, the relative carcinogenicity varies within the series of dibenzanthracenes, and benzo[g]chrysene appears to be more active than benzo[c]chrysene A number of components of the process oils play important roles in the upgrading processes. Hydrogenated compounds such as tetralin are hydrogen donor solvents for coal liquefaction (5). Cracked gas oils containing highly aromatic compounds are often composed of discontinuous fractions in discrete boiling point ranges. For example
Miniature Toroidal Radio Frequency Ion Trap Mass Analyzer
A miniature ion trap mass analyzer is reported. The described analyzer is a 1/5-scale version of a previously reported toroidal radio frequency (rf) ion trap mass analyzer. The toroidal ion trap operates with maximum rf trapping voltages about 1 kVp-p or less; however despite the reduced dimensions, it retains roughly the same ion trapping capacity as conventional 3D quadrupole ion traps. The curved geometry provides for a compact mass analyzer. Unit-mass resolved mass spectra for n-butylbenzene, xenon, and naphthalene are reported and preliminary sensitivity data are shown for naphthalene. The expected linear mass scale with rf amplitude scan is obtained when scanned using a conventional mass-selective instability scan mode combined with resonance ejection
Infrared renormalons and analyticity structure in pQCD
Relation between the infrared renormalons, the Borel resummation
prescriptions, and the analyticity structure of Green functions in perturbative
QCD (pQCD) is investigated. A specific recently suggested Borel resummation
prescription resulted in the Principal Value and an additional power-suppressed
correction that is consistent with the Operator Product Expansion. Arguments
requiring the finiteness of the result for any power coefficient of the leading
infrared renormalon, and the consistency in the case of the absence of that
renormalon, require that this prescription be modified. The apparently most
natural modification leads to the result represented by the Principal Value.
The analytic structure of the amplitude in the complex coupling plane, obtained
in this way, is consistent with that obtained in the literature by other
methods.Comment: 6 pages, revtex4, 1 eps-figure; improved version - the paragraph
containing Eqs.(18) and (19) is new, as well as the next paragraph; the Title
modified; some references added; version to appear in Phys. Rev.
A Paul Trap Mass Analyzer Consisting of Two Microfabricated Electrode Plates
We report the design and performance of a novel radiofrequency (RF) ion trap mass analyzer, the planar Paul trap, in which a quadrupolar potential distribution is made between two electrode plates. Each plate consists of a series of concentric, lithographically deposited 100-micrometer-wide metal rings, overlaid with a thin resistive layer. To each ring is applied a different RF amplitude, such that the trapping field produced is similar to that of the conventional Paul trap. The accuracy and shape of the electric fields in this trap are not limited by electrode geometry nor machining precision, as is the case in traps made with metal electrodes. The use of two microfabricated plates for ion trap construction presents a lower-cost alternative to conventional ion traps, with additional advantages in electrode alignment, electric field optimization, and ion trap miniaturization. Experiments demonstrate the effects of ion ejection mode and scan rate on mass resolution for several small organic compounds. The current instrument has a mass range up to ~180 Thompsons (Th), with better than unit mass resolution over the whole range
Long-term correction of ornithine transcarbamylase deficiency by WPRE-mediated overexpression using a helper-dependent adenovirus
The urea cycle disorders (UCDs) are important models for developing gene replacement therapy for liver diseases. Long-term correction of the most common UCD, ornithine transcarbamylase (OTC) deficiency, has yet to be achieved in clinical or preclinical settings. The single human clinical trial using early-generation adenovirus (Ad) failed to show any biochemical correction. In adult OTC-deficient mice, an E1/E2-deleted Ad vector expressing the mouse OTC gene, but not the human, was only transiently therapeutic. By using post-transcriptional overexpression in the context of the less immunogenic helper-dependent adenoviral vector, we achieved metabolic correction of adult OTC-deficient mice for \u3e6 months. Demonstrating this result were normalized orotic aciduria, normal hepatic enzyme activity, and elevated OTC RNA and protein levels in the absence of chronic hepatotoxicity. Overexpressing the human protein may have overcome two potential mechanisms accounting for poor cross-species complementation: a kinetic block at the level of mitochondrial import or a dominant negative effect by the mutant polypeptide. These data represent an important approach for treating human inborn errors of hepatocyte metabolism like the UCDs that require high-level transduction and gene expression for clinical correction
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