36 research outputs found

    Non-invasive single-bunch matching and emittance monitor

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    On-line monitoring of beam quality for high brightness beams is only possible using non-invasive instruments. For matching measurements, very few such instruments are available. One candidate is a quadrupole pick-up. Therefore, a new type of quadrupole pick-up has been developed for the 26 GeV Proton Synchrotron (PS) at CERN, and a measurement system consisting of two such pick-ups is now installed in this accelerator. Using the information from these pick-ups, it is possible to determine both injection matching and emittance in the horizontal and vertical planes, for each bunch separately. This paper presents the measurement method and some of the results from the first year of use, as well as comparisons with other measurement methods.Comment: 10 pages, 10 figures; added figure, minor textual additions; To be resubmitted to Phys. Rev. ST-A

    Design and implementation of the international genetics and translational research in transplantation network

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    Speaking with a forked tongue about multilingualism in the language policy of a South African university

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    As part of a broader student campaign for ‘free decolonized education’, protests over language policies at select South African universities between 2015 and 2016 belied widespread positive appraisals of these policies, and revealed what is possibly an internal contradiction of the campaign. The discourse prior to the protests (e.g. “excellent language policies but problematic implementation”), during the protests (e.g. silence over the role of indigenous African languages in the “Afrikaans must fall” versus “Afrikaans must stay” contestations), and after the protests (e.g. English becoming a primary medium in some institutional policy reviews) warrant attention to critical literacy in language policy scholarship. Based on a theoretical account of speaking with a forked tongue, this article analyzes the language policy text of one South African university. The analysis suggests, simultaneously, why similar policies have tended to be positively appraised, why students’ calls for policy revisions were justified, but why the changes clamoured for arguably amount to complicity in self-harm

    Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

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    Background: In addition to HLA genetic incompatibility, non-HLA difference between donor and recipients of transplantation leading to allograft rejection are now becoming evident. We aimed to create a unique genome-wide platform to facilitate genomic research studies in transplant-related studies. We designed a genome-wide genotyping tool based on the most recent human genomic reference datasets, and included customization for known and potentially relevant metabolic and pharmacological loci relevant to transplantation. Methods: We describe here the design and implementation of a customized genome-wide genotyping array, the ‘TxArray’, comprising approximately 782,000 markers with tailored content for deeper capture of variants across HLA, KIR, pharmacogenomic, and metabolic loci important in transplantation. To test concordance and genotyping quality, we genotyped 85 HapMap samples on the array, including eight trios. Results: We show low Mendelian error rates and high concordance rates for HapMap samples (average parent-parent-child heritability of 0.997, and concordance of 0.996). We performed genotype imputation across autosomal regions, masking directly genotyped SNPs to assess imputation accuracy and report an accuracy of >0.962 for directly genotyped SNPs. We demonstrate much higher capture of the natural killer cell immunoglobulin-like receptor (KIR) region versus comparable platforms. Overall, we show that the genotyping quality and coverage of the TxArray is very high when compared to reference samples and to other genome-wide genotyping platforms. Conclusions: We have designed a comprehensive genome-wide genotyping tool which enables accurate association testing and imputation of ungenotyped SNPs, facilitating powerful and cost-effective large-scale genotyping of transplant-related studies. Electronic supplementary material The online version of this article (doi:10.1186/s13073-015-0211-x) contains supplementary material, which is available to authorized users

    Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

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    Smart Housing and Social Sustainability: Learning from the Residents of Queensland's Research House

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    One fifth of greenhouse gas emissions in Australia are generated by the everyday activities of households (Commonwealth of Australia 2005a). Higher consumer awareness of the impact of housing on the environment (Commonwealth of Australia 2003, 2005b) and of sustainable housing alternatives (The State of Queensland 2005a) is essential. One of the drawbacks to mainstreaming ecologically sustainable housing designs is consumer resistance, based on perceptions of eco- or green- housing as being less aesthetically pleasing, and less economically attractive for resale than traditional housing (Minnery et al. 2003). This paper reports findings from a small social study about the experiences of a family who lived in ‘Research House’, Australia, for a two year period monitoring product performance and household economies in a sustainable house. Residents reported satisfaction and improved feelings of safety when living in the spacious, airy and secure home, providing feedback to enable product improvement and assist consumer decision-making about sustainable housing

    Know My Name

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    Universally acclaimed, rapturously reviewed, and an instant New York Times bestseller, Chanel Miller\u27s breathtaking memoir gives readers the privilege of knowing her not just as Emily Doe, but as Chanel Miller the writer, the artist, the survivor, the fighter. (The Wrap). Her story of trauma and transcendence illuminates a culture biased to protect perpetrators, indicting a criminal justice system designed to fail the most vulnerable, and, ultimately, shining with the courage required to move through suffering and live a full and beautiful life. Know My Name will forever transform the way we think about sexual assault, challenging our beliefs about what is acceptable and speaking truth to the tumultuous reality of healing. Entwining pain, resilience, and humor, this memoir will stand as a modern classic.https://corescholar.libraries.wright.edu/dlpp_all/1755/thumbnail.jp

    Exploring College Student Identity among Young People with Foster Care Histories and Mental Health Challenges

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    Young adults with foster care histories experience unique barriers to success in postsecondary academic settings, including higher rates of mental health challenges. This study reports the perspectives of college students with foster care histories and self-identified mental health concerns (N = 18) about how these factors relate to their post-secondary academic experiences. Study participants describe managing their mental health amid other academic and life stressors, share their perspectives on campus-based support and help-seeking experiences, and highlight the need for acknowledgement of their foster care identities in conjunction with their developing college student identities. Participants make a case for programming to help with managing challenges related to overwhelming emotions in response to compounding stressors, balancing self-reliance with help-seeking when needed, and developing interpersonal relationships that reduce feelings of otherness in the campus context. Recommendations for improving student experiences include mental health services provided by people familiar with the lived experience of foster care, access to foster student-specific programs providing social, emotional, and academic support, and campus-wide efforts improve the conditions for academic success in the face of difficult personal histories and elevated mental health challenges

    Exploring College Student Identity Among Young People With Foster Care Histories and Mental Health Challenges

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    For this study, researchers from Pathways Research and Training Center at Portland State University explored the perspectives of college students with foster care histories and self-identified mental health conditions. Researchers aimed to better understand how the relationship between students’ foster care identity and their newly forming student identities might impact academic success. We conducted interviews with students participating in the FUTURES intervention efficacy study, which evaluated the impact of a 9-month self-determination coaching program for students enrolled in their first two years of college at Portland State University, Portland Community College, or Mt. Hood Community College. Interview participants (N=18) were 72% female, 78% identified as non-white or mixed race, and 28% identified as LGBTQIA. The research team conducted thematic analysis of the interview transcripts by iteratively organizing inductive codes into broader themes and developing related findings. Four themes were developed related to the complexities of the foster student experience – including mental health challenges and other life stressors, and their impact on developing student identities in postsecondary education

    Smart Housing and Social Sustainability: Learning from the Residents of Queensland's Research House

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    One fifth of greenhouse gas emissions in Australia are generated by the everyday activities of households (Commonwealth of Australia 2005a). Higher consumer awareness of the impact of housing on the environment (Commonwealth of Australia 2003, 2005b) and of sustainable housing alternatives (The State of Queensland 2005a) is essential. One of the drawbacks to mainstreaming ecologically sustainable housing designs is consumer resistance, based on perceptions of eco- or green- housing as being less aesthetically pleasing, and less economically attractive for resale than traditional housing (Minnery et al. 2003). This paper reports findings from a small social study about the experiences of a family who lived in ‘Research House’, Australia, for a two year period monitoring product performance and household economies in a sustainable house. Residents reported satisfaction and improved feelings of safety when living in the spacious, airy and secure home, providing feedback to enable product improvement and assist consumer decision-making about sustainable housing
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