Crossing the race divide : interracial sex in antebellum Savannah

This article explores the social significance of inter-racial sexual contact in an antebellum Southern city. How did inter-racial sex challenge the established social hierarchy in Savannah? Was it a controversial issue, viewed as a threat to the social order, or was it accepted as an inevitable evil resulting from a mixed population residing in close proximity

Decay of Pressure Fluctuation in the Hyporheic Zone around a Cylinder

Erosion around a submerged cylinder is a well-studied problem, and is of particular interest in bridge pier scour applications. Particles erode when lift and drag forces overcome a critical threshold. These forces are typically studied from above the water-riverbed interface and are related to geometry and surficial processes. The present study maps hyporheic pressure fluctuations as they are related to surface water velocity fluctuations. Relatively, high-pressure events in the subsurface promote a destabilizing force from within the riverbed and increase the potential for the mobilization of sediment. Differential pressure transducers were fitted within a vertical cylinder in a movable bed flume. The pressure ports were flush with the cylinder surface and below the water-sand interface. The three orthogonal components of velocity were recorded synchronously with differential pressure measured over a 15 mm depth. As expected, results show decay in pressure fluctuations as a function of depth

Memory B cells and CD8⁺ lymphocytes do not control seasonal influenza A virus replication after homologous re-challenge of rhesus macaques.

This study sought to define the role of memory lymphocytes in the protection from homologous influenza A virus re-challenge in rhesus macaques. Depleting monoclonal antibodies (mAb) were administered to the animals prior to their second experimental inoculation with a human seasonal influenza A virus strain. Treatment with either anti-CD8α or anti-CD20 mAbs prior to re-challenge had minimal effect on influenza A virus replication. Thus, in non-human primates with pre-existing anti-influenza A antibodies, memory B cells and CD8α⁺ T cells do not contribute to the control of virus replication after re-challenge with a homologous strain of influenza A virus

Synthesis, structures and cytotoxicity studies of p-sulfonatocalix[4]arene lanthanide complexes

A number of p-sulfonatocalix[4]arene complexes of the lanthanides (Tb, Gd, and Eu) have been prepared, some in the presence of tetraazamacrocycle 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid (DO3A), and fully characterised. Crystal structure determinations reveal lanthanide coordination at the sulfonate group, bridging several calixarene units, giving coordination polymers. All complexes in this study have been determined to be relatively non-toxic using in vitro cell assays with CC₅₀ values in the range 30–170 μM