Enhancement of primary production in the North Atlantic outside of the spring bloom, identified by remote sensing of ocean colour and temperature

Peer reviewedPublisher PD

Quasilinear theory of the 2D Euler equation

We develop a quasilinear theory of the 2D Euler equation and derive an integro-differential equation for the evolution of the coarse-grained vorticity. This equation respects all the invariance properties of the Euler equation and conserves angular momentum in a circular domain and linear impulse in a channel. We show under which hypothesis we can derive a H-theorem for the Fermi-Dirac entropy and make the connection with statistical theories of 2D turbulence.Comment: 4 page

Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey

Background Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine concentrations than men. Methods We investigated the relationship between dose, body mass index (BMI), plasma glucose concentration, and plasma clozapine and N-desmethylclozapine (norclozapine) concentrations in 100 individuals with a severe enduring mental illness. Results Mean (10th/90th percentile) plasma clozapine concentrations were higher for women [0.49 (0.27–0.79) mg/L] compared with men [0.44 (0.26–0.70) mg/L] (F = 2.2; p = 0.035). There was no significant gender difference in the prescribed clozapine dose. BMI was significantly higher in women [mean (95 % CI) = 34.5 (26.0–45.3)] for females compared with 32.5 (25.2–41.0) for males. Overall, BMI increased by 0.7 kg/m 2 over a mean follow-up period of 210 days. A lower proportion, 41 % of women had a fasting blood glucose ≤6.0 mmol/L (<6.0 mmol/L is defined by the International Diabetes Federation as normal glucose handling), compared with 88 % of men (χ2  = 18.6, p < 0.0001). Conclusions We have shown that mean BMI and blood glucose concentrations are higher in women prescribed clozapine than in men. Women also tended to attain higher plasma clozapine concentrations than men. The higher BMI and blood glucose in women may relate to higher tissue exposure to clozapine, as a consequence of sex differences in drug metabolism

Modeling programming knowledge for mentoring at scale

In large programming classes, MOOCs or online communities, it is challenging to find peers and mentors to help with learning specific programming concepts. In this paper we present first steps towards an automated, scalable system for matching learners with Python programmers who have expertise in different areas. The learner matching system builds a knowledge model for each programmer by analyzing their authored code and extracting features that capture domain knowledge and style. We demonstrate the feasibility of a simple model that counts the references to modules from the standard library and Python Package Index in a programmers' code. We also show that programmers exhibit self-selection using which we can extract the modules a programmer is best at, even though we may not have all of their code. In our future work we aim to extend the model to encapsulate more features, and apply it for skill matching in a programming class as well as personalizing answers on StackOverflow.Massachusetts Institute of Technology. Undergraduate Research Opportunities Progra

Analysis of multistory frames with light gauge steel panel infills

PREFACE This report was originally presented as a thesis to the Faculty of the Graduate School of Cornell University in partial fulfillment of the requirements for the degree of Doctor of Philosophy, conferred in August 1972. The author wishes to thank Professor Arthur H. Nilson, Project Director, and Professor Robert G. Sexsmith, Principal Investigator, for the help and guidance that made this work possible. This investigation was supported by the American Iron and Steel Institute

Aerosol Data Sources and Their Roles within PARAGON

We briefly but systematically review major sources of aerosol data, emphasizing suites of measurements that seem most likely to contribute to assessments of global aerosol climate forcing. The strengths and limitations of existing satellite, surface, and aircraft remote sensing systems are described, along with those of direct sampling networks and ship-based stations. It is evident that an enormous number of aerosol-related observations have been made, on a wide range of spatial and temporal sampling scales, and that many of the key gaps in this collection of data could be filled by technologies that either exist or are expected to be available in the near future. Emphasis must be given to combining remote sensing and in situ active and passive observations and integrating them with aerosol chemical transport models, in order to create a more complete environmental picture, having sufficient detail to address current climate forcing questions. The Progressive Aerosol Retrieval and Assimilation Global Observing Network (PARAGON) initiative would provide an organizational framework to meet this goal

Interspecific Hybridization And The Evolutionary Origin Of A Gynogenetic Fish, Poecilia Formosa

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137459/1/evo04029.pd