Self-Efficacy and Grade Point Average in Relationship to Academic Success in Baccalaureate Nursing Students

Academic success, defined as the completion of a nursing program and passing the National Council for Licensure Examination for Registered Nurses (NCLEX-RN), is the goal of all nursing programs. The identification of specific variables related to academic success could identify students at risk of failing early. The purpose of this research study was to explore the relationship of two variables related to academic success, self-efficacy and grade point averages (GPA), in accelerated and regular BSN students. The results of this study suggest that a statistically significant, positive relationship exists between prerequisite GP A and self-efficacy of BSN students. In addition, the results suggest that a statistically significant difference existed between the prerequisite GP A of the accelerated and the regular nursing students. The conclusion of this research suggests that the combination of self-efficacy and prerequisite grades provides one opportunity for early identification and intervention of at risk students

Findings for the Cleveland Achieve Model: Implementation and Early Impacts of an Employer-Based Approach to Encourage Employment Retention Among Low-Wage Workers

An on-site retention program at long-term nursing care facilities had little effect overall on retention of low-wage employees, aside from a small increase in retention in the short term and among subgroups with particularly high turnover rates

Employment Retention and Advancement Project: Results from the Personal Roads to Individual Development and Employment (PRIDE) Program in New York City

A random assignment study of a welfare-to-work program for recipients with work-limiting medical and mental health conditions shows that participants had increased employment and decreased welfare payments

A Preliminary Look at Early Educational Results of the Opportunity NYC - Family Rewards Program: A Research Note for Funders

Targeted toward very low-income families in six high-poverty New York City communities, Family Rewards offers cash payments tied to efforts and achievements in children's education, family preventive health care practices, and parents' employment. This paper reviews data on participants' receipt of rewards and offers preliminary estimates of the program's impacts on selected educational outcomes during the first year

Strategies to Help Low-Wage Workers Advance: Implementation and Early Impacts of the Work Advancement and Support Center (WASC) Demonstration

Work Advancement and Support Center (WASC) is an innovative strategy to help low-wage workers increase their incomes by stabilizing employment, improving skills, increasing earnings, and easing access to work supports. In its first year, WASC connected more workers to food stamps and publicly funded health care coverage and, in one site, substantially increased training activities

The Employment Retention and Advancement Project: Results from the Substance Abuse Case Management Program in New York City

Participants in an intensive care management program for public assistance recipients with substance abuse problems were slightly more likely to enroll in treatment than participants in less intensive services. However, the intensive program had no effects on employment or public benefit receipt among the full sample

EXTREMIST RECRUITMENT AND EXTREMIST SENTIMENT NORMALIZATION

On November 23, 2022, Dr. Cynthia Miller-Idriss, Director of the Polarization and Extremism Research and Innovation Lab (PERIL) at American University, presented on Extremist Recruitment and Extremist Sentiment Normalization. The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives. The key points discussed were conceptualisation and context of far-right extremism, the development and trends of the movement globally, and suggested directions for prevention.   Received: 2022-12-27Revised: 2023-01-0

The role of protein kinase A in hypoxia-induced PC-12 cell death.

Hypoxia is characterized by an inadequate oxygen supply to the tissues in proportion to their metabolic needs, and is a primary factor in traumatic CNS injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The cAMP-dependent protein kinase (PKA) has been attributed a role as an antiapoptotic kinase as well as a pro-apoptotic signal. Thus the role of PKA in hypoxia-induced cell survival is currently unclear. We show here that hypoxia induces cell death in WT PC-12 cells, pheochromocytoma cells used as a model of the oxygen-sensitive carotid body glomus cells. The onset of cell death following 24 hours of severe, sustained hypoxia also correlated with an increase in oxidative stress and a drop in ATP levels. Inactivation of PKA in the 123.7 PC-12 cell line prevented the hypoxiainduced ROS surge, energy depletion, and cell death. PKA activity thus contributes to hypoxia~induced cell death in WT cells via enhanced ROS production and energy depletion, but was not shown to playa role in the regulation of cellular antioxidant mechanisms. 123.7 cells had lower levels of hypoxia-induced glucose utilization and lactate release than WT cells, thus PKA appears to stimulate increases in glycolytic flux during hypoxia. Mitochondrial potentials were higher in 123.7 cells than in WT cells, indicating that PKA inhibits mitochondrial metabolism. Furthermore, the expression of COX IV was decreased by hypoxic exposure in both cell types, but was significantly greater in 123.7 cells. The greater expression of COX IV may allow 123.7 cells to maintain mitochondrial electron flow and energy production under drastically reduced oxygen conditions. Antioxidant treatment blocked hypoxia-induced cell death, but was not sufficient to prevent depletion of ATP or to modulate the metabolic pathways. Thus, this finding indicates that hypoxia-induced metabolic regulation and energy depletion occur independently of oxidative stress. Consequently, the PKA signaling pathway appears to contribute to hypoxia-induced cell death through its regulatory effects on oxidative stress and metabolic pathways. Modulation of the PKA signaling pathway could provide novel therapeutic strategies to improve cellular adaptation and recovery in the many pathologies characterized by periods of hypoxia