The State of Outdoor Recreation in Utah 2020

The purpose of this report is to provide a high-level review of the trends that define outdoor recreation within Utah. We do this by distilling data from a variety of sources, focusing on ‘key metrics’ that can be tracked over time, serving as a finger on the pulse on the health of outdoor recreation within Utah. Data on outdoor recreation participation and its benefits and impacts varies considerably across the state depending upon the managing agency collecting the data. This report focuses on statewide data available for outdoor recreation opportunities provided on lands managed by the Bureau of Land Management, National Park Service, US Fish and Wildlife Service, USDA Forest Service, and Utah State Parks. We highlight data unique to administrative units (e.g., national parks or forests) where applicable. The report focuses on four sets of key metrics: 1) Participation; 2) Economics; 3) Infrastructure; and 4) Gateway and Natural Amenity Region (GNAR) communities

Bears Ears and Outdoor Recreation in San Juan County

The creation and subsequent downsizing of Bears Ears National Monument has been one of the most publicized and politicized land management decisions within the state over the past decade. However, relatively little research has been conducted to determine if, and to what extent, the creation of the monument impacted outdoor recreation and recreation-related industries. Now, more than three years after the monument was created, there are sufficient data to take a retrospective look at the influence of the monument. The purpose of this research is to evaluate the influence of Bears Ears National Monument on outdoor recreation and its related industries in San Juan County, Utah

Efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute pain after orthopedic trauma: A practice management guideline from the Eastern Association for the Surgery of Trauma and the Orthopedic Trauma Association

OBJECTIVES: Fracture is a common injury after a traumatic event. The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) to treat acute pain related to fractures is not well established. METHODS: Clinically relevant questions were determined regarding NSAID use in the setting of trauma-induced fractures with clearly defined patient populations, interventions, comparisons and appropriately selected outcomes (PICO). These questions centered around efficacy (pain control, reduction in opioid use) and safety (non-union, kidney injury). A systematic review including literature search and meta-analysis was performed, and the quality of evidence was graded per the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. The working group reached consensus on the final evidence-based recommendations. RESULTS: A total of 19 studies were identified for analysis. Not all outcomes identified as critically important were reported in all studies, and the outcome of pain control was too heterogenous to perform a meta-analysis. Nine studies reported on non-union (three randomized control trials), six of which reported no association with NSAIDs. The overall incidence of non-union in patients receiving NSAIDs compared with patients not receiving NSAIDs was 2.99% and 2.19% (p=0.04), respectively. Of studies reporting on pain control and reduction of opioids, the use of NSAIDs reduced pain and the need for opioids after traumatic fracture. One study reported on the outcome of acute kidney injury and found no association with NSAID use. CONCLUSIONS: In patients with traumatic fractures, NSAIDs appear to reduce post-trauma pain, reduce the need for opioids and have a small effect on non-union. We conditionally recommend the use of NSAIDs in patients suffering from traumatic fractures as the benefit appears to outweigh the small potential risks

An Assessment of the Location of the Bears Ears National Monument Cultural Center

A cultural center at Bears Ears National Monument, if well planned, could serve as an anchor destination through which visitors could learn about, experience, and appreciate the cultures, histories, and landscapes that define southeastern Utah. A cultural center also holds the potential to bolster the regional economy, by signaling a long-term investment in the sustainability of the region’s outdoor recreation and tourism industry. Our intent with this analysis is to establish a foundational understanding of potential locations for a cultural center. We develop and analyze a set of cultural, environmental, and economic metrics that can be used to shape ongoing discussions about the potential locations for the Bears Ears National Monument cultural center. Our analysis shows markedly different potential siting locations depending upon whether cultural, environmental, or economic considerations are given priority. When all three considerations are equally weighed, there are several notable “hot spots” near Bluff, south and west of Blanding, and west of Monticello. We describe the advantages and disadvantages associated with each of these potential locations. Ultimately, we hope the work we have completed here can be used to shape ongoing discussions about the potential locations for the Bears Ears National Monument cultural center

2019 Outlook and Analysis Letter: The Vital Statistics of America\u27s State Park Systems

The annual Outlook and Analysis Letter presents the ‘vital statistics’ that characterize the operation and use of the nation’s 50 state park systems. In the report the authors detail historical trends relevant to state park system management using data within the Annual Information Exchange (AIX) archive

What are the benefits and risks of inhaled corticosteroids for COPD?

Q: What are the benefits and risks of inhaled corticosteroids for COPD? A: Inhaled corticosteroids (ICS), either alone or with a long-acting [beta] agonist (LABA), reduce the frequency of exacerbations of chronic obstructive pulmonary disease (COPD) and statistically, but not clinically, improve quality of life (QOL) (strength of recommendation [SOR]: B, meta-analyses of heterogeneous studies). However, ICS have no mortality benefit and don't consistently improve forced expiratory volume in 1 second (FEV1) (SOR: B, meta-analyses of secondary outcomes). They increase the risk of pneumonia, oropharyngeal candidiasis, and bruising (SOR: B, meta-analyses of secondary outcomes). Withdrawal of ICS doesn't significantly increase the risk of COPD exacerbation (SOR: B, a meta-analysis)

Outdoor Recreation Use and Indicators of the Ecological, Physical, and Social Characteristics of Recreation Settings in the Central Wasatch: Phase 1 Interim Report

The purpose of this study is to explore how outdoor recreation use and its associated impacts can be quantified and monitored over time within the canyons. Establishing indicators of the ecological, physical, and social characteristics of recreation settings throughout the canyons is an essential first step to quantifying and monitoring change. Our goal is to establish a set of indicators that are collaboratively generated and grounded in the best-available science and reflect the unique needs and concerns of the diverse stakeholders and interest groups who use, manage, and depend on the canyons. Through the work detailed below, the Central Wasatch Commission, the State of Utah, and the Uinta-Wasatch-Cache National Forest will gain a clear understanding of what data on outdoor recreation use currently exist and what data are essential to understand the ecological, physical, and social characteristics of recreation settings

Subject preferences of fifth-grade children.

Thesis (Ed.M.)--Boston University N.B.:Pages 155 and 309 are missing from original thesis

A framework for improving early detection of breast cancer in sub-Saharan Africa: A qualitative study of help-seeking behaviors among Malawian women

Many women in Africa are diagnosed with advanced breast cancer. We explored Malawian breast cancer patients’ perspectives about their diagnosis and ability to access care to identify help-seeking behaviors and to describe factors influencing delay

Cryogel scaffold-mediated delivery of adipose-derived stem cells promotes healing in murine model of atrophic non-union

Non-union is defined as the permanent failure of a bone to heal and occurs clinically in 5% of fractures. Atrophic non-unions, characterized by absent/minimal callus formation, are poorly understood and difficult to treat. We recently demonstrated a novel murine model of atrophic non-union in the 3.6Col1A1-tk (Col1-tk) mouse, wherein dosing with the nucleoside analog ganciclovir (GCV) was used to deplete proliferating osteoprogenitor cells, leading to a radiographic and biomechanical non-union after the mid-shaft femur fracture. Using this Col1-tk atrophic non-union model, we hypothesized that the scaffold-mediated lentiviral delivery of doxycycline-inducible BMP-2 transgenes would induce osteogenesis at the fracture site. Cryogel scaffolds were used as a vehicle for GFP+ and BMP-2+ cell delivery to the site of non-union. Cryogel scaffolds were biofabricated through the cross-linking of a chitosan-gelatin polymer solution at subzero temperatures, which results in a macroporous, spongy structure that may be advantageous for a bone regeneration application. Murine adipose-derived stem cells were seeded onto the cryogel scaffolds, where they underwent lentiviral transduction. Following the establishment of atrophic non-unions in the femurs of Col1-tk mice (4 weeks post-fracture), transduced, seeded scaffolds were surgically placed around the site of non-union, and the animals were given doxycycline water to induce BMP-2 production. Controls included GFP+ cells on the cryogel scaffolds, acellular scaffolds, and sham (no scaffold). Weekly radiographs were taken, and endpoint analysis included micro-CT and histological staining. After 2 weeks of implantation, the BMP-2+ scaffolds were infiltrated with cartilage and woven bone at the non-union site, while GFP+ scaffolds had woven bone formation. Later, timepoints of 8 weeks had woven bone and vessel formation within the BMP-2+ and GFP + scaffolds with cortical bridging of the original fracture site in both groups. Overall, the cell-seeded cryogels promoted osseous healing. However, while the addition of BMP-2 promoted the endochondral ossification, it may provide a slower route to healing. This proof-of-concept study demonstrates the potential for cellularized cryogel scaffolds to enhance the healing of non-unions