ESCOCIA (Reino Unido). Mapas generales (1745). 1:830000

Dedicatoria : "To His Royal Highness William Duke of Cumberland Commander in Chief of His Majesty's Forces This Map of North Britain is most humbly Dedicated by his Royal Highnesses most Faithful & most Obedt. Servant And. Millar"Escala gráfica de 30 millas geograficas de 60 al grado [0 6,7 cm]. Coordenadas referidas a los meridianos de Ferro (E 9°52''--E 16°55'/N 59°30'--N 54°35') y Paris (O 10°09'--O 3°05'). Red geográfica de 20' en 20' Orientado con lis en rosa de ocho vientosOrografía de perfilIndica sondas batimétricas, veriles, bajos y bancos de arenaLos límites entre los distintos condados aparecen diferenciados mediante coloresAparece trazada la línea de derrota entre las costas británicas y NoruegaConsta una nota sobre las observaciones que han servido de base para el levantamiento de la cartaTítulo enmarcado en cartela flanqueada por personajes mitológicos, y dedicatoria en cartela barroca, coronada por un blasón nobiliarioInserta : Shetland Islands. Escala [ca. 1:975000], 1 minuto de latitud [= 0,19 cm

LOTHIAN (Reino Unido). Escocia. Región. Mapas generales. 1745. 1:135000

Dedicatoria "To the Right Honble. John Earl of Stair Field Marshal & Commander in Chief of his Majesty's Forces in South Britain & C. This Map of the Lothians, shewing the March of the Rebels & Battle of Prestan Is inscribd by your Lordshps. most Obliged & most Obedt. Humble Servt. And. Miller"Escalas gráficas de 10 millas comunes escocesas de 60 al grado, 12 millas de 72 al grado y 8 millas escocesas de 48 al grado [= 13,8 cm]. Coordenadas referidas al meridiano de Edimburgo (O 0°34'--E 0°47'/n 56°13'--N 55°43'). Red geográfica de 5' en 5'. Orientado con lis en rosa de treinta y dos vientosOrografía por perfil. Veriles, bajos y bancos de arenaClave alfabética para indicar la posición de los componentes rebeldes y lealesLímites entre los distintos condados diferenciados por coloresTítulo y dedicatoria enmarcados en sendas cartelas barroca

Practical evaluation of SEEK and OpenBIS for biological data management in SynthSys; first report

Author contributions: ET and TZ evaluated systems and developed software; IC, PS and AJM provided use cases; AJM and TZ designed the evaluation; ET, TZ and AJM wrote the report with input from all authors. Acknowledgements: We gratefully acknowledge training and support from the SEEK and OpenBIS project teams, who also checked this document.The project evaluated two existing data management systems for a small set of users, who represent diverse needs within the SynthSys Centre, in order to inform wider adoption for biological research. SEEK’s strengths are support for the Investigation, Study, Assay (ISA) standard and a fine grained access control. This makes SEEK an excellent tool for collaborative work and publishing results. OpenBIS is well suited for automatic metadata processing and incorporation into analysis workflows. Both data management systems provided useful and complementary functionality, so our recommendation is that both are hosted for use in SynthSys. This also aligns well with the EU FAIRDOM project which is currently integrating SEEK and OpenBIS into one platform

Changing planetary rotation rescues the biological clock mutant lhy cca1 of Arabidopsis thaliana

Author contributions. AJM and SKH designed the study. JC and WVT performed experiments and analysed data under supervision of SKH. AJM performed additional analysis and wrote the paper. Acknowledgements. We are grateful to Kieron Edwards and Adrian Thomson for performing the experiments shown in Figure 3, to Tomasz Zielinski for the online BioDare resource and to members of the Millar laboratory for data curation in BioDare.Background: Pervasive, 24-hour rhythms from the biological clock affect diverse biological processes in metabolism and behaviour, including the human cell division cycle and sleep-wake cycle, nightly transpiration and energy balance in plants, and seasonal breeding in both plants and animals. The clock mechanism in the laboratory model plant species Arabidopsis thaliana is complex, in part due to the multiple interlocking, negative feedback loops that link the clock genes. Clock gene mutants are powerful tools to manipulate and understand the clock mechanism and its effects on physiology. The LATE ELONGATED HYPOCOTYL and CIRCADIAN CLOCK ASSOCIATED 1 genes encode dawn-expressed, Myb-related repressor proteins that delay the expression of other clock genes until late in the day. Double mutant plants (lhy cca1) have low-amplitude, short-period rhythms that have been used in multiple studies of the plant circadian clock. Results: We used in vivo imaging of several luciferase (LUC) reporter genes to test how the rhythmic gene expression of wild-type and lhy cca1 mutant plants responded to light:dark cycles. Red, blue and red+blue light were similarly able to entrain these gene expression rhythms. The timing of expression rhythms in double mutant plants showed little or no response to the duration of light under 24h light:dark cycles (dusk sensitivity), in contrast to the wild type. As the period of the mutant clock is about 18h, we tested light:dark cycles of different duration (T cycles), simulating altered rotation of planet Earth. lhy cca1 double mutants regained as much dusk sensitivity in 20h T cycles as the wild type in 24h cycles, though the phase of the rhythm in the mutants was much earlier than wild type. The severe, triple lhy cca1 gi mutants also regained dusk sensitivity in 20h cycles. The double mutant showed some dusk sensitivity under 28h cycles. lhy cca1 double mutants under 28h cycles with short photoperiods, however, had the same apparent phase as wild-type plants. Conclusion: Simulating altered planetary rotation with light:dark cycles can reveal normal circadian performance in clock mutants that have been described as arrhythmic under standard conditions. The features rescued here comprise a dynamic behaviour (apparent phase under 28h cycles) and a dynamic property (dusk sensitivity under 20h cycles). These conditional clock phenotypes indicate that parts of the clock mechanism continue to function independently of LHY and CCA1, despite the major role of these genes in wild-type plants under standard conditions. Accessibility: Most results here will be published only in this format, citable by the DOI. Data and analysis are publicly accessible on the BioDare resource (www.biodare.ed.ac.uk), as detailed in the links below. Transgenic lines are linked to Stock Centre IDs below (Table 7)

The weed community affects yield and quality of soybean (Glycine max (L.) Merr.)

The relationship between the weed community and soybean (Glycine max (L.) Merr.) seed yield and quality was assessed in two soybean experiments in Illinois, USA. One field was sown with different proportions of target weeds (Ambrosia trifida L., Amaranthus rudis J. Sauer, Setaria faberi F. Herrm), and the other was naturally infested with these and other weeds. The composition of the weed communities in both fields were compared to final yield and quality (% protein, oil, and water) of the crop using NMDS ordination. Biomass and canopy cover, and seed quality (% protein, relative water content, seed weight) of the crop, were related to the multivariate structure of the weed community in both experiments. Lower quality soybeans were harvested from plots dominated by the target weeds and a suite of subordinate volunteers. Analysis restricted to the volunteer weed community was also significantly related to seed protein and seed weight. Similar results from the two experiments lend generality to the findings and indicate that soybean producers need to manage the composition of the weed community