11 research outputs found
HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus-infected individuals
High Prevalence of Skin Disorders among HTLV-1 Infected Individuals Independent of Clinical Status
Unusual non-fluorescent broad spectrum siderophore activity (SID EGYII) by Pseudomonas aeruginosa strain EGYII DSM 101801 and a new insight towards simple siderophore bioassay
The seed endosphere of Anadenanthera colubrina is inhabited by a complex microbiota, including Methylobacteriumspp. and Staphylococcus spp. with potential plant-growth promoting activities
Background and aims Plant seeds are emerging micro–habitats, whose importance as reservoir and vector of beneficial microbes just begins to be recognized. Here we aimed to characterize the bacterial microbiota of the Anadenanthera colubrina seed endosphere, with special focus to beneficial traits and to the colonization pattern. Methods Cultivation–dependent (isolation from surface–sterilized seeds) and cultivation–independent (pyrosequencing
of 16S rRNA gene from metagenomic seed DNA) analyses, functional tests and microscopical investigations (fluorescence in situ hybridization coupled with confocal laser scanning microscopy (FISH-CLSM) were performed. Results We isolated several Methylobacterium and Staphylococcus spp., exhibiting both plant growth promotion and antimicrobial activities. The two taxonomic groups showed complementary traits, which supports a functional selection. Both genera were detected also by pyrosequencing, together with further taxa. The genera Friedmaniella, Bifidobacterium, Delftia, Anaerococcus and Actinomyces appeared here for the first time as seed endophytes. We detected bacterial cells
and micro–colonies in seed cryosections by FISHCLSM. Alphaproteobacteria, Firmicutes and other bacteria colonized intercellular spaces of the parenchyma and associated to transport vessels. Conclusions This work sheds light onto the diversity, functions and colonization pattern of the Anadenanthera colubrina seed endophytes, and strongly suggest a role as beneficial partners for seed-associated microbiot
Lesões dermatolĂłgicas em pacientes infectados pelo vĂrus linfotrĂłpico humano de cĂ©lulas T do tipo 1 (HTLV-1) Dermatologic lesions in patients infected with the human T-cell lymphotropic vĂrus type 1 (HTLV-1)
O vĂrus linfotrĂłpico humano de cĂ©lulas T do tipo 1 (HTLV-1) Ă© o primeiro retrovĂrus isolado do ser humano. Descreveu-se, em pouco tempo, o seu papel etiolĂłgico em algumas doenças, com destaque para a leucemia/linfoma de cĂ©lulas T do adulto (ATLL), a mielopatia associada ao HTLV-1/paraparesia espástica tropical (HAM/TSP) e a uveĂte associada ao HTLV-1 (HAU). Na dĂ©cada de 90, o HTLV-1 foi associado a eczema grave da infância, conhecido como dermatite infecciosa (DI). Desde entĂŁo, diversos outros tipos de lesões cutâneas tĂŞm sido observados em pacientes infectados pelo HTLV-1, em especial, nos doentes de HAM/TSP ou de ATLL. PorĂ©m, mesmo portadores assintomáticos do vĂrus apresentam doenças dermatolĂłgicas. Excetuando-se a dermatite infecciosa, nĂŁo há lesĂŁo da pele especĂfica da infecção pelo HTLV-1. Aqui, os autores apresentam as principais lesões dermatolĂłgicas descritas em pacientes infectados pelo HTLV-1, destacando o valor epidemiolĂłgico e clĂnico desses achados.<br>Human T-cell Lymphotropic vĂrus type I (HTLV-1) was the first human retrovĂrus described. Some time after its discovery a group of diseases were related to this vĂrus, such as, adult T-cell leukemia lymphoma (ATLL), HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 associated uveitis (HAU). In the nineties, HTLV-1 was associated to a severe eczema of children, called infective dermatitis (ID). Since then, several other skin manifestations have been observed in HTLV-1-infected individuals, particularly in patients with ATLL or HAM/TSP. However, according to some reports, dermatologic lesions are also common in asymptomatic HTLV-1 carriers. Besides ID, all other skin lesions reported are nonspecific. The aim of this review is to outline the dermatologic manifestations reported in HTLV-1 infected patients, emphasizing the clinical and epidemiological value of these findings