Evaluation of Latex Agglutination Inhibition Reaction Test for Urinary Methamphetamine

A latex agglutination inhibition reaction test for a screening method of methamphetamine in urine has been reported by Aoki et al. An evaluation of this method was attempted by using gas chromatography and chemical ionization mass fragmentography. Some false negative and false positive cases were found. It seems that this method needs some modification for false negative cases and also it needs a confirmation test

A Case of Death After Glue Sniffing

A 25-year-old male, a thinner and/or glue sniffer, was found dead in the bathtub of his house approximately 24 hr after abusing a glue. As the cause of death was unknown, an autopsy of the deceased was performed. The ingredients of the glue in the tissue and organs were analyzed by gas chromatography and gas chromatographymass spectrometry. Toluene, n-hexane and methylcyclopentane in the mesenterial fat were confirmed by gas chromatography-mass spectrometry, and the toluene concentration analyzed by gas chromatography was 10.9 μ,gig in the blood and 50.0 μ,gig in the brain. The cause of death was considered to be suffocation or acute cardiac failure under the effect of toluene

A Rapid and Sensitive Method for Detecting Fenitrothion in Biological Fluids Using the Phosphorus-Sulfur Selective Detector: a fenitrothion intoxication case

Fenitrothion (sumithion) in biological fluids of a patient, who attempted suicide by ingesting of fenitrothion, was separated and purified by Extrelut® column extraction. A gas chromatograph equipped with a flame photometric detec1 or and a gas chromatograph-mass spectrometer were used for a detection of fenitrothion. A 41-year-old female, who attempted suicide by ingesting about 30 ml of Sumithion® (40% fenitrothion), started to vomit spontaneously and recurringly, and was transported to a hospital 3 hr after the ingestion. The patient was almost fully conscious and the diameter of her pupils was 3 mm on both sides. The fenitrothion concentration in the blood sample was 260 ng/g and was less than 6 ng/g in the urine sample both of which were collected 4 hr after ingestion. Aminofenitrothion, 4-nitro-3-methyl phenol, S-methylfenitrothion, phenobarbital and lidocaine were identified in the ethyl ether extract of the urine sample. After ingestion, the serum cholinesterase activity (normal range: 175-440 IU) was 104 at hr, 38 at 1 day, 85 at 2 days, 102 at 3 days and 137 at 4 days

Adjustment process of reasonable accommodation for students with disability

本研究の一部はJSPS科研費15K01683の助成を受けた。 本研究の一部は第45回中国四国大学保健管理研究集会（平成27年８月，徳島市），並びに第53回全国大学保健管理研究集会（平成27年９月，盛岡市）で発表した

A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere

The Chemical Events Working Group of the Global Health Security Initiative has developed a flexible screening tool for chemicals that present a risk when accidentally or deliberately released into the atmosphere. The tool is generic, semi-quantitative, independent of site, situation and scenario, encompasses all chemical hazards (toxicity, flammability and reactivity), and can be easily and quickly implemented by non-subject matter experts using freely available, authoritative information. Public health practitioners and planners can use the screening tool to assist them in directing their activities in each of the five stages of the disaster management cycle

シンナー遊びをしたのち泳いでいて死亡した1例

A 25-year-old male, a thinner abuser, swam in a pond just after thinner-sniffing and he drowned. Death from drowning was confirmed by diatoms in the lung and kidney. The drowning would seem to be induced by the effect of considerable high concentrations of toluene, absorbed into the body from thinner-sniffing, in tissues of the cadaver

分光光度法による一酸化炭素ヘモグロビン飽和度測定のための試料の選択

Carboxyhemoglobin (HbCO) saturation in a liquid specimen collected at medicolegal autopsy was analyzed firstly by a spectrophotometric method, which was first reported by Fretwurst et al, modified by Fukui and then modified by the authors, and secondly by a carbon monoxide-total hemoglobin (CO-Total Hb) method developed by the authors. In 70 blood specimens collected from the heart or blood vessels of 59 cadavers, the values obtained by the spectrophotometric method were similar to those obtained by the CO-Total Hb method with the exception of three blood specimens, two of which were markedly putrefied and the other considerably denatured by heat, in which the values obtained by the spectrophotometric method were significantly higher than those by the CO-Total Hb method. In 62 specimens of reddish discolored body cavity fluids collected from 31 cadavers, nearly all values obtained by the spectrophotometric method were much higher than those obtained by the CO-Total Hb method. The results indicate that the spectrophotometric method should not be used for the quantitative determination of HbCO in body cavity fluids, blood mixed with body cavity fluid, or blood markedly denatured by putrefaction or heat

A Medicolegal Case of Anorexia Nervosa

A highly emaciated 37-year-old female had swerved while cycling to avoid an oncoming car and fallen on her face. The following day she died at home. She had not been examined by a physician. Because of the circumstances, intracranial injuries were suspected and a medicolegal autopsy was performed. However, no fatal injuries to the brain or other organs were found, and the cause of death appeared to be malnutrition. The malnutrition, according to her past history and the autopsy and histopathological findings, was apparently due to anorexia nervosa